754 results match your criteria: "Pleomorphic Parotid Adenoma Imaging"

Although myoepithelioma is defined as a benign tumour made up primarily of neoplastic myoepithelial cells, its actual histopathological characteristics are highly diverse. It can be considered a rare disease. The most common site of occurrence is the parotid gland, followed by the minor salivary glands of the palate.

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Background/aim: Parotid oncocytomas typically present as benign, unilateral, slow-growing, painless, and solitary masses that are histologically firm and multilobulated. They are often misdiagnosed as pleomorphic adenomas, hemangiomas, or other forms of oncocytosis. However, in our case, the parotid oncocytomas initially mimicked bilateral parotid gland metastasis of advanced oropharyngeal cancer.

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Purpose: To assess the diagnostic potential of the synthetic MRI (SyMRI) for differentiating Warthin's tumors (WT) from pleomorphic adenomas (PA).

Materials And Methods: Forty-nine individuals with parotid gland tumors (PA, n = 23; WT, n = 26) were recruited. Using two distinct regions of interest (ROI), SyMRI quantitative parameters of lesions were calculated, including mean and standard deviation (T1, T2, PD, T1sd, T2sd, and PDsd).

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Subcutaneous Pleomorphic Adenoma in an Accessory Parotid Gland in the Cheek.

Plast Reconstr Surg Glob Open

October 2024

From the Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School Hospital, Tokyo, Japan.

The accessory parotid gland (APG) is a distinct salivary tissue in the cheek that is located on the masseter muscle and is separate from the main parotid gland. APG tumors (APGTs) are rare. Due to aesthetic reasons and the risk of both malignancy and recurrence, APGTs are best treated with surgical resection.

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Clinical and Morphological Aspects of Aggressive Salivary Gland Mixed Tumors: A Narrative Review.

Diagnostics (Basel)

September 2024

Department of Microscopic-Morphology-Morphopathology, ANATPATMOL Research Center, "Victor Babeș" University of Medicine and Pharmacy Timișoara, Eftimie Murgu Square, No. 2, 300041 Timișoara, Romania.

Salivary gland tumors are a rare and heterogeneous group of neoplasms of the head and neck region. The mixed category of these tumors include the following entities: pleomorphic adenoma (PA), carcinoma ex pleomorphic adenoma (CEPA), salivary carcinosarcoma (CS), and metastasizing PA (MPA). The most common benign tumor of the salivary glands is PA.

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Diagnostic performance of MRI-based radiomics models using machine learning approaches for the triple classification of parotid tumors.

Heliyon

September 2024

Department of Medical Imaging, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510030, Guangdong, China.

Rationale And Objectives: Preoperative differentiation of malignant tumors (MT), pleomorphic adenomas (PA), and other benign tumors of the parotid gland is critical to clinical strategy, this study aimed to develop and validate a T2-weighted image (T2WI) based radiomics model through machine learning approaches for the triple classification of parotid gland tumors.

Materials And Methods: We retrospectively enrolled 147 patients from January 2010 to July 2022. T2WIs were used to extract radiomics features.

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Introduction: Currently, the diagnosis of salivary gland tumors using imaging techniques is unreliable.

Methods: In this monocentric retrospective study, we examined patients who received a Ga-DOTATOC PET/CT and subsequently underwent a salivary gland tumor resection between 1 January 2010 and 31 December 2021. PET/CT image assessment was compared with somatostatin receptor (SSTR) expression and histology.

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Purpose: This study aimed to investigate whether multiparametric magnetic resonance imaging (MRI) including dynamic contrast-enhanced (DCE) and diffusion weighted (DW) MRI can differentiate pleomorphic adenoma (PA) from schwannoma in the parapharyngeal space.

Methods: Forty-six patients with pathologically proven PAs and 47 schwannomas in the parapharyngeal space were enrolled. All patients underwent conventional MRI, and DW-MRI and DCE-MRI were performed in 30 and 33 patients, respectively.

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When neglected for a long time, salivary gland pleomorphic adenoma (PA) can attain a considerable size, increasing the patient's morbidity along with the risk of malignant transformation. Very few case reports are available describing PA of the parotid glands presenting as a large cervicofacial mass. We report a case of epithelial myoepithelial carcinoma -a rare subtype of carcinoma ex-PA (Ca-Ex-PA) of non-luminal differentiation, that developed over a long period in a primary PA of the parotid gland and presented as a giant cervicofacial mass.

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Purpose: To evaluate the effectiveness of MRI-based radiomics models in distinguishing between Warthin tumors (WT) and misdiagnosed or ambiguous pleomorphic adenoma (PA).

Methods: Data of patients with PA and WT from two centers were collected. MR images were used to extract radiomic features.

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Article Synopsis
  • - Salivary gland tumors are rare with varied types and behaviors, mainly found in the parotid gland, and about 54-79% are benign, with pleomorphic adenoma being the most common.
  • - Malignant tumors frequently include adenoid cystic carcinomas and mucoepidermoid carcinomas, requiring detailed evaluation due to their complex characteristics.
  • - The review discusses advancements in diagnostic methods for these tumors, including imaging, clinical examinations, fine needle aspirations, and the use of artificial intelligence in histopathological analysis.
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Predicting High-risk Capsular Features in Pleomorphic Adenoma of the Parotid Gland Through a Nomogram Model Based on ADC Imaging.

Acad Radiol

November 2024

The First Affiliated Hospital of Jinan University, Clinical Research Platform for Interdiscipline of Stomatology, School of Stomatology, Jinan University, Guangzhou 510630, PR China. Electronic address:

Rationale And Objectives: Based on Apparent Diffusion Coefficient (ADC) images, a nomogram model is established to accurately predict the high-risk capsular characteristics associated with pleomorphic adenoma of the parotid gland (PAP) recurrence.

Materials And Methods: This retrospective study analyzed 190 patients with PAPs. Significant clinical radiological factors were identified through univariate difference analysis and multivariate regression analysis.

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Primary malignant melanoma of the parotid gland, a rare case arising from a duct: a case report and literature review.

Front Oncol

June 2024

Department of Oral and Maxillofacial Radiology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea.

Malignant melanoma of the parotid gland is an unusual tumor in the head and neck region, and most parotid melanoma is reported as a metastatic lesion of cutaneous malignant melanoma. We report a case of primary malignant melanoma arising in the parotid gland duct with diagnostic challenge. The patient was a 68-year-old man who complained of repeated right facial swelling that presented 3 months prior.

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Article Synopsis
  • The study aimed to evaluate how extracellular volume fraction (ECV) and arterial enhancement fraction (AEF) from enhanced CT can help distinguish between pleomorphic adenoma (PA) and atypical parotid adenocarcinoma (PCA) before surgery.
  • Researchers analyzed 187 cases of parotid tumors, using both clinical and CT image data to create different models for diagnosis, including combinations of clinical features with ECV and AEF.
  • Findings showed that the combined model (clinical features plus ECV and AEF) outperformed the clinical-only model in identifying the tumors, suggesting that including these CT-derived metrics enhances diagnostic accuracy.
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Multi-feature Fusion Network on Gray Scale Ultrasonography: Effective Differentiation of Adenolymphoma and Pleomorphic Adenoma.

Acad Radiol

November 2024

Department of Ultrasonography, The First Affiliated Hospital of Nanchang University, Nanchang, China; Department of Ultrasonography, GanJiang New District Peoples Hospital, Nanchang, China. Electronic address:

Article Synopsis
  • The study aimed to create a deep learning radiomics network (DLRN) that combines ultrasound images, radiomics, and clinical features to differentiate between parotid pleomorphic adenoma (PA) and adenolymphoma (AL).
  • A total of 287 patients were used in various cohorts for training and validating machine learning classifiers that generated different models, including logistic regression and deep learning radiomics models.
  • The DLRN model outperformed other models in distinguishing between PA and AL, demonstrating a significant enhancement in diagnostic accuracy and providing an important non-invasive solution for clinicians.
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Article Synopsis
  • * A 56-year-old man initially diagnosed with MLPS in his left calf developed a painless mass in his left parotid gland two months post-surgery, leading to a misdiagnosis of pleomorphic adenoma.
  • * The mass was ultimately confirmed as a metastasis of MLPS through advanced testing methods, highlighting the complexities and challenges in diagnosing this rare lesion.
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Background: Pleomorphic adenoma (PA) is a common parotid tumor, yet due to the relative rarity of deep lobe PA (DLPA), there is a paucity of information about its clinical presentation and surgical outcomes.

Methods: We reviewed the charts of patients with previously untreated parotid PA between the years 1990 and 2015. Clinical parameters and surgical outcomes were compared between superficial lobe PA (SLPA) and DLPA.

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Parotid lumps are a heterogeneous group of mainly benign but also malignant tumors. Preoperative imaging does not allow a differentiation between tumor types. Multispectral optoacoustic tomography (MSOT) may improve the preoperative diagnostics.

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Article Synopsis
  • * The USEML model was validated with 203 patients and showed superior performance with an AUC of 0.891 compared to traditional ultrasound and clinical models, as well as outperforming physician assessments.
  • * The findings indicate that the USEML model, which combines clinical, ultrasound, and radiomic features, is effective for preoperative diagnostics of PMA and WT, enhancing treatment planning for patients.
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Correlation between MRI (DWI and DCE) and cellularity of parotid gland pleomorphic adenomas.

Eur Arch Otorhinolaryngol

May 2024

Department of Oto-Rhino-Laryngology-Head and Neck Surgery, La Conception University Hospital, AP-HM, Aix-Marseille University, Marseille, France.

Purpose: Parotid pleomorphic adenomas present a risk of recurrence, higher when the tumour is a hypocellular subtype. The aim of the study was to determine whether it is possible to characterize this histological subtype with diffusion and perfusion sequences of the preoperative MRI.

Methods: This retrospective study included 97 patients operated between 2010 and 2020.

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