Construction and Performance Study of an Injectable Dual-Network Hydrogel Dressing with Inherent Drainage Function.

With the widespread utilization of moist wound dressings, the extended healing time and increased risk of wound infection caused by excessively moist environments have garnered significant attention. The development of hydrogel dressings that can effectively control the wound moisture level and promote healing is very important. Inspired by the pore-opening perspiration effect of the skin, this study constructed an injectable dual-network hydrogel, CMCS-OSA/AG/MXene, by the composition of a dynamic covalent network of carboxymethyl chitosan and oxidized sodium alginate based on the Schiff base and hydrogen bond network of the thermosensitive low-melting-point agar with the advantage of the upper critical solution temperature (UCST) effect.

Construction and Performance Study of a Dual-Network Hydrogel Dressing Mimicking Skin Pore Drainage for Photothermal Exudate Removal and On-Demand Dissolution.

In recent years, negative pressure wound dressings have garnered widespread attentions. However, it is challenging to drain the accumulated fluid under negative pressures for hydrogel dressings. To address this issue, this study prepared a chemical/physical duel-network PEG-CMCS/AG/MXene hydrogel composed by chemical disulfide crosslinked network of four-arm polyethylene glycol/carboxymethyl chitosan (4-Arm-PEG-SH/CMCS), and the physical network of hydrogen bond of agar (AG).

Morphological Changes of the Temporomandibular Joint and Masseter Muscle After Mandibular Angle Osteotomy.

Mandibular angle osteotomy with outer cortex grinding is an effective cosmetic procedure for correcting square faces. However, morphological changes in the mandible may also cause temporomandibular joint (TMJ) disorders. This retrospective study aimed to investigate the morphological stabilization of the TMJ and changes in masseter muscle thickness after mandibular angle osteotomy to evaluate the safety of the procedure.

Electroactive injectable hydrogel based on oxidized sodium alginate and carboxymethyl chitosan for wound healing.

Electroactive hydrogel is of great significance in restoring wound currents, promoting cell proliferation, and accelerating the wound healing process. However, the poor dispersity and underlying toxicity of electronic conductive fillers and high concentration of ionic conductors in traditional electroactive hydrogel limited its application in medical care. Herein, an electroactive oxidized sodium alginate/carboxymethyl chitosan/silver nanoparticles (OSA/CMCS/AgNPs) hydrogel was constructed with no additional conductive fillers or synthesized conductive polymers being added, in which the dynamic imine bonds were rapidly formed between aldehyde groups in OSA and amino groups in CMCS, and AgNPs were further in situ formed by UV irradiation.

Correlation between white blood cell count at admission and mortality in COVID-19 patients: a retrospective study.

Background: Coronavirus disease-19 (COVID-19) has become a world health threaten. Its risk factors with death were still not known. White blood cells (WBC) count as a reflection of inflammation has played a vital role in COVID-19, however its level with death is not yet investigated.

Epicanthoplasty With Rotated-advanced-back Cut Flap.

Background: Epicanthoplasty is one of the most popular cosmetic surgeries in Asia. The aim of this study was to present a rotated, advanced, back cut flap (R-A-B flap) that leads to correct the congenital epicanthus effectively with satisfactory results.

Methods: From January of 2017 to December of 2018, we performed the modified cut back flap epicanthoplasty to correct epicanthus.

Resurfacing Large Skin Defects of the Face and Neck by Optimizing the Utilization of Expanded Forehead Axial-Pattern Flap and Cervicofacial Local Flap.

It is very common for plastic surgeons to experience faciocervical defect, which could be quite challenging and should be processed with a good result. Expanded local flap and expanded axial-pattern flap from the forehead are both applied widely in the reconstruction of faciocervical region. It is crucial to choose appropriate techniques and treat the deformities effectively in the clinical practice.

Prevalence of Different Forms and Involved Bones of Craniofacial Fibrous Dysplasia.

Background: The purposes of this study were to analyze the prevalence of various craniofacial bones involved in patients with craniofacial fibrous dysplasia (CFD) and to demonstrate the most common form and bone involvement in patients with CFD for surgeons.

Methods: To address the research purpose, the authors designed and performed a systematic review with meta-analysis. A comprehensive electronic search without date was performed in August 2013.

[Study on culture, identification and differentiation of primary rat skeletal muscle satellite cells].

Objective: To establish the isolation, culture and identification methods of primary rat skeletal muscle satellite cells (SMSC) and observe its characterization of differentiation in vitro.

Methods: Skeletal muscle satellite cells were obtained by tissue block culture method in combination with pre-plating techniques, and the purity of these cells was detected by both immunocytochemistry and fluorescence activated cell sorter (FACS) with Pax7 as marker of SMSC. Myogenesis of these cells was induced in differentiation medium and the mRNA expressions of myogenic differentiation gene (MyoD) and Myogenin were determined by Real-time polymerase chain reaction (PCR).

Novel technique to narrow the wide midface in Asians.

Purpose: To develop a novel technique for narrowing the wide midface in Asians using virtual surgical planning (VSP) and 2-bent plate fixation.

Materials And Methods: A total of 19 patients with a wide midface underwent midface narrowing by VSP and 2-bent plate fixation from 2009 to 2013. In each case, a 3-dimensional spiral computed tomography (CT) scan of the skull was obtained before surgery.

Melasma-like hyperpigmentation induced by intense pulsed light treatment in Chinese individuals.

Background: Symmetric melasma-like hyperpigmentation (MLH) has been identified in several patients following intense pulsed laser (IPL) treatment sessions. These patients exhibited no typical signs of melasma prior to IPL therapy.

Objectives: To investigate the incidence of MLH in Chinese patients receiving IPL treatment and to discuss potential causative factors for this condition and potential preventive measures.

Pre-expanded cervico-acromial fasciocutaneous flap based on the supraclavicular artery for resurfacing post-burn neck scar contractures.

Objective: Post-burn cicatricle contractures of neck pose a challenge for plastic and reconstructive surgeons. To improve functional and cosmetic results, and to minimize the donor-site morbidity, we use pre-expanded cervico-acromial fasciocutaneous flap based on the supraclavicular artery as a feasible choice for resurfacing large skin defects of the neck.

Methods: In this series, from 2008 to 2012, 18 patients with ages ranging between 11 and 42 years (20 flaps with 2 patients in bilateral fashion) suffering from post-burn scar contractures of the neck were treated.

Dextran-coated fluorapatite nanorods doped with lanthanides in labelling and directing osteogenic differentiation of bone marrow mesenchymal stem cells.

Terbium (Tb) or europium (Eu)-doped fluorapatite nanorods (Tb/Eu-FHA) were prepared using a hydrothermal method. The structure, morphology, and luminescence of the products were determined using X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), and photoluminescence spectra (PL). The surfaces of the Tb/Eu-FHA nanorods were further conjugated with hydrophilic cationic polymers, such as dextran, to enhance hydrophilicity, biocompatibility and cell penetration.

Clinical characteristics of craniomaxillofacial fibrous dysplasia.

Background: The clinical characteristics of craniomaxillofacial fibrous dysplasia (FD) have not been clearly identified. The objective of this meta-analysis is to assess the predominance of the monostotic form of FD using an evidence-based review. Furthermore, we examined the laterality and sex dominance of FD in patients from international study populations.

Hemimandibular hyperplasia: classification and treatment algorithm revisited.

Hemimandibular hyperplasia (HH) is a developmental asymmetry characterized by three-dimensional enlargement of one half of the mandible. The hyperplastic side usually involves the condyle, condylar neck, ramus, and body, with the anomaly terminating abruptly at the symphysis. The malformation results in the clinical presentation of ipsilateral enlargement of the mandible and tilted occlusal plane, associated with a deviated chin to the contralateral side.

Strategy to minimize oral mucosal tear and lip injury in facial contouring and orthognathic surgery.

In this article, the authors present a simple but effective technical strategy to protect the lip and mucosa from iatrogenic thermal injury and traumatic mucosal tear in orthognathic and aesthetic facial contouring surgery. During surgical exposure and osteotomy, a piece of double-layered Vaseline dressing gauze is strategically placed over the lip and mucosal tissues before the application of the Obwegeser or Gimma retractors. The objective is to avoid traumatic and thermal injury to the lip and mucosal tissues during the use of various retractors and other craniomaxillofacial dynamic instruments in such surgery.

Female predominance and effect of sex on Parry-Romberg syndrome.

Parry-Romberg syndrome (PRS) is a rare craniofacial disorder whose etiology has not been well understood. The objective of this study was to evaluate the sex difference and the scope of female predominance in PRS. The study used meta-analysis to examine 838 diverse patients from 26 articles.

Upper-lip vermilion reconstruction with a modified cross-lip vermilion flap in hemifacial atrophy.

Lip-vermilion reconstruction is part of the comprehensive treatment of progressive hemifacial atrophy. In this study, we described a two-stage reconstruction procedure to address the defect of the upper lip in patients with hemifacial atrophy, using a modified cross-lip vermilion flap with the pedicle specifically positioned at the commissure for functional and aesthetic purposes. During the first stage of surgery, a pre-determined mucosal flap from the lower lip with a vascular pedicle containing an inferior labial artery and the surrounding orbicularis oris muscle cuff were raised and transposed to reconstruct the upper-vermilion defect.

Aesthetic mental and cervical reconstruction after severe acne inversa by using a bilateral pedicled expanded forehead flap.

Acne inverse (AI), also known as hidradenitis suppurativa, is characterized by inflammatory nodules, fistulating sinus tracts, and painful skin abscesses. The severe AI often produces disfiguring scars influenced in both the appearance and function, especially in the facial and cervical regions. There might be difficulties in the situation for surgical treatment.

Feasibility of absorbable plates and screws for fixation in reduction malarplasty with L-shaped osteotomy.

Reduction malarplasty with L-shaped osteotomy has been widely applied to correct malar prominence because of its simple manipulation, satisfactory outcome, and few complications in east Asians. Secondary surgery for the removal of titanium miniplates or microplates and screws is often needed because of the drawbacks of implants. To overcome the disadvantage, the authors applied absorbable plates and screws instead of titanium fixation system and evaluated the feasibility of them.

Reconstruction of partial-thickness vermilion defects with a mucosal V-Y advancement flap based on the orbicularis oris muscle.

Repair of a large, trauma-induced partial-thickness vermilion defect is considered a challenging task. Ideally, such defects should be corrected by methods that use tissues similar in colour and texture to the normal vermilion. When the length of a defect is greater than half that of the vermilion and the width of the defect is greater than 1.

Epicanthoplasty with double eyelidplasty incorporating modified Z-plasty for Chinese patients.

Background: Blepharoplasty, without correction of the epicanthal folds, weakens the aesthetic appearance of the results. Hence, a modified Z-plasty procedure with double eyelidplasty was carried out for different degrees of epicanthus.

Methods: From 2005 to 2010, the authors performed epicanthoplasties using the modified Z-plasty and double eyelidplasty for 322 Chinese patients.