6,028 results match your criteria: "Placenta Previa"
The impact of indication for cesarean on blood loss.
Am J Obstet Gynecol
October 2024
Department of Obstetrics and Gynecology, Baylor College of Medicine and Texas Children's Hospital, Houston, TX. Electronic address:
Article Synopsis
- Postpartum hemorrhage is a major cause of maternal death globally, and accurate blood loss assessment during cesarean deliveries is crucial for better outcomes.
- This study analyzed 4,881 cesarean deliveries to investigate if the reasons for the surgeries influence blood loss and postpartum hemorrhage risk, categorizing cases into seven specific indications.
- Results showed that cesareans due to labor arrest had the highest blood loss, significantly more than elective cases, highlighting the importance of indication in estimating and managing postpartum hemorrhage risks.
Antenatal maternal serum biomarkers as a predictor for placenta accreta spectrum disorders.
Placenta
December 2024
Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand. Electronic address:
Article Synopsis
- Placenta accreta spectrum (PAS) is a serious condition where the placenta abnormally attaches to the uterine wall, leading to risks like severe postpartum hemorrhage; diagnosing PAS often requires expert imaging techniques, which are lacking in some areas.
- A study was conducted to assess the effectiveness of specific maternal plasma protein biomarkers (AT-3, PAI-I, sVEGFR-2, sT-2) for screening pregnant women at high risk for PAS, focusing on those with placenta previa.
- The results indicated that combining these biomarkers with a history of cesarean delivery achieved the best screening performance for PAS, with 77% sensitivity and 89% specificity.
Obstetric and neonatal outcomes in women with Ankylosing spondylitis - an evaluation of a population database.
BMC Pregnancy Childbirth
October 2024
Department of Obstetrics and Gynecology, McGill University, 845 Rue Sherbrooke, O, Montreal, Montréal, Quebec, QC, 3HA 0G4, Canada.
Article Synopsis
- Ankylosing Spondylitis (AS) is a chronic disease affecting the spine and pelvis, and while it's not rare in women of childbearing age, the effects on pregnancy are not well understood.
- A study analyzed data from over 9 million pregnancies between 2004 and 2014 to compare outcomes for women with AS against those without the condition.
- Findings showed that women with AS had higher rates of cesarean delivery, gestational diabetes, placenta previa, and adverse neonatal outcomes like small-for-gestational-age infants and intrauterine fetal death.
Epidemiology and risk factors for healthcare-associated maternal peripartum infections in Ukraine: results a multicenter study.
Pol Merkur Lekarski
October 2024
Shupyk National Healthcare University of Ukraine, Kyiv, Ukraine.
Article Synopsis
- * Out of 3600 vaginal deliveries, 600 (16.7%) cases of maternal peripartum infections were recorded, predominantly occurring after hospital discharge, with endometritis being the most prevalent infection.
- * Key risk factors identified for these infections included high body mass index, placenta previa, prolonged rupture of membranes, and various pregnancy-related conditions.
Diagnosis and Analysis of Vasa Previa Types With Flow HD Glass Body.
J Ultrasound Med
October 2024
Department of Ultrasound, Zibo Municipal Hospital, Zibo, China.
Article Synopsis
- The study aims to assess the effectiveness of flow high definition (HD) glass body imaging for detecting vasa previa in prenatal diagnoses and discusses different types of the condition.
- A total of 15 vasa previa cases were identified, including various configurations of umbilical vessels, with some vessels re-positioning during later gestation scans.
- Flow HD glass body imaging proved superior in visualizing the relationships between vasa previa, the cervix, and placenta, allowing for better determination of umbilical vessel types compared to traditional methods.
Firsttrimester Diagnosis and Therapy @ 11 - 13 Weeks of Gestation - Part 1 : Guideline of the DEGUM, ÖGUM, SGUMGG, DGGG, ÖGG, Gynecologie Suisse, DGPM, DGPGM, BVF, ACHSE (AWMF S2e LL 085-002 1.1.2024) (https://register.awmf.org/de/leitlinien/detail/085-002).
Geburtshilfe Frauenheilkd
October 2024
ACHSE Wissensnetzwerk, ACHSE, Berlin, Germany.
Article Synopsis
Firsttrimester Diagnosis and Therapy @ 11 - 13 Weeks of Gestation - Part 2 : Guideline of the DEGUM, ÖGUM, SGUMGG, DGGG, ÖGG, Gynecologie Suisse, DGPM, DGPGM, BVF, ACHSE (AWMF S2e LL 085-002 1.1.2024) (https://register.awmf.org/de/leitlinien/detail/085-002).
Geburtshilfe Frauenheilkd
October 2024
ACHSE Wissensnetzwerk, ACHSE, Berlin, Germany.
Article Synopsis
- The AWMF 085-002 S2e-guideline provides detailed recommendations based on high-quality studies for screening and managing pregnancy complications during the 11-13 weeks of gestation scan.
- Key topics include screening for anatomical malformations, chromosomal defects, preeclampsia, and other conditions, with solutions for identifying many issues already in place.
- While some complications can be effectively screened and managed in early pregnancy, challenges remain in identifying disorders related to glucose metabolism and preterm birth, making early detection crucial for better outcomes in pregnancy management.
Cesarean hysterectomy in pregnancies complicated with placenta previa accreta: a retrospective hospital-based study.
BMC Pregnancy Childbirth
October 2024
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.
Article Synopsis
- Placenta previa accreta (PPA) can lead to severe blood loss during cesarean hysterectomy, sometimes requiring the procedure to prevent life-threatening hemorrhage.
- A study of 199 women undergoing cesarean sections found that factors like emergency surgery, cervical invasion of the placenta, and bladder injury increased the risk of excessive blood loss.
- Conversely, techniques like balloon occlusion of the iliac arteries and aortic balloon occlusion appeared to reduce the risk of significant blood loss during surgery.
Firsttrimester Diagnosis and Therapy @ 11-13+6 Weeks of Gestation - Part 1.
Ultraschall Med
October 2024
ACHSE Wissensnetzwerk, ACHSE, Berlin, Germany.
Article Synopsis
- - The AWMF 085-002 S2e-guideline provides detailed recommendations based on high-quality studies for screening and diagnosing various pregnancy-related issues between 11-13 weeks of gestation, including anatomical malformations and chromosomal defects.
- - It emphasizes the importance of first-trimester screening for complications such as preeclampsia, abnormal placentation, and growth retardation, noting that some identification methods are effective while others, like glucose metabolism disorders, remain insufficient.
- - The guideline also highlights that early diagnosis allows for better management of pregnancy complications, including the option for lower-risk terminations if needed, and reassures parents through appropriate follow-ups, reducing unnecessary examinations.
Firsttrimester Diagnosis and Therapy @ 11-13+6 Weeks of Gestation - Part 2.
Ultraschall Med
October 2024
ACHSE Wissensnetzwerk, ACHSE, Berlin, Germany.
Article Synopsis
- The AWMF 085-002 S2e-guideline provides evidence-based recommendations for diagnosing and managing various pregnancy complications during the critical 11-13 week scan.
- It covers topics such as screening for anatomical malformations, chromosomal defects, preeclampsia, and other significant conditions, providing clarity on how to identify these issues.
- While many screening challenges have been addressed, some like glucose metabolism disorders and preterm birth remain unresolved, emphasizing the importance of early screening for better pregnancy management.
Prenatal detection of placenta accreta spectrum using a sonographic checklist.
Acta Obstet Gynecol Scand
October 2024
Department of Fetal Medicine, National Maternity Hospital, Dublin, Ireland.
Article Synopsis
- The study evaluates a proposed ultrasound checklist for detecting placenta accreta spectrum (PAS) in patients with a high likelihood of the condition, aiming to see how effective it is in identifying confirmed PAS cases.
- Conducted over five years, the research included patients who had ultrasound assessments for PAS suspicion, with diagnoses confirmed through surgical and histopathological findings.
- Results showed an 80.7% PAS diagnosis among participants, with the third-trimester ultrasound displaying a sensitivity of 84% and specificity of 73%, highlighting key ultrasound features—abnormal placental lacunae and myometrial thinning—as strongly associated with PAS.
Risk Factors of Velamentous Cord Insertion in Singleton Pregnancies-A Systematic Review and Meta-Analysis.
J Clin Med
September 2024
Third Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Agiou Dimitriou, 54124 Thessaloniki, Greece.
Article Synopsis
- This meta-analysis investigates the risk factors associated with velamentous cord insertion (VCI), aiming to improve prenatal identification of the condition.
- It included data from 14 cohort and 4 case-control studies, encompassing over 952,000 singleton pregnancies, revealing an overall VCI prevalence of 1.54%.
- Key risk factors identified include assisted reproductive technology, being a first-time mother (nulliparity), smoking, and having placenta previa, which could help refine screening strategies for women at greater risk.
Clinical Features Between Primary Obstetric Antiphospholipid Syndrome and Non-Criteria Obstetric Antiphospholipid Syndrome and Risk Factors of Adverse Pregnancy Outcomes: A Retrospective Study of 1006 Cases.
Am J Reprod Immunol
September 2024
The Reproductive Medical Center, Department of Obstetrics and Gynecology, West China Second Hospital of Sichuan University, Chengdu, Sichuan, China.
Article Synopsis
- The study aimed to compare the pregnancy outcomes and clinical characteristics of patients with primary obstetric antiphospholipid syndrome (OAPS) and those with primary non-criteria obstetric antiphospholipid syndrome (NC-OAPS).
- Researchers analyzed data from 141 OAPS patients and 865 NC-OAPS patients to identify risks for adverse pregnancy outcomes (APO) using univariable and logistic regression analyses.
- Results showed that OAPS patients had a higher risk of stillbirth, while NC-OAPS patients faced more preterm births and overall APO; distinct risk factors were identified for each group, suggesting the need for tailored management strategies.
P-glycoprotein expression is decreased in placenta accreta and placenta previa disorders.
Minerva Obstet Gynecol
September 2024
Department of Biomedical, Experimental and Clinical Sciences "Mario Serio, " University of Florence, Florence, Italy.
Background: P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) are multidrug resistance (MDR) transporters that function as placental gatekeepers, lowering the fetal levels of diverse xenobiotics and toxins that may be circulating in the maternal blood throughout pregnancy. Placenta accreta spectrum (PAS) and the placenta previa (PP) disorders are obstetric pathologies encompassed by an abnormal invasion of chorionic villous tissue in the uterine wall or at the endocervical os, respectively. Given the fact that MDR transporters are involved in placentation and are highly responsive to inflammation, we hypothesized that immunostaining of P-gp and BCRP would be altered in PAS and in PP specimens.
View Article and Find Full Text PDF[Changes in the rates of preterm birth and multiparity over a 10-year period and multiparity as a possible risk factor for preterm birth].
Zhonghua Fu Chan Ke Za Zhi
September 2024
Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.
Article Synopsis
- - This study analyzed preterm birth rates and the frequency of multipara (women who have given birth more than once) over 10 years at Peking University First Hospital, revealing an overall preterm birth rate of 8.3% that has increased, with peaks in 2017 and 2018.
- - It was found that multipara is a significant risk factor for spontaneous preterm birth, specifically before 37 and 34 weeks of pregnancy, alongside other risks like multiple pregnancies and cervical incompetence.
- - Compared to first-time mothers, multipara tend to be older, have earlier deliveries, higher rates of premature births, and their pregnancies experience different complications, including a higher incidence of gestational diabetes mellitus.
Influencing factors of glycemic control in singleton pregnancies complicated by gestational diabetes mellitus in western China: A retrospective study.
Medicine (Baltimore)
September 2024
Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
To investigate the factors influencing glycemic control in gestational diabetes mellitus (GDM) patients and their impacts on pregnancy outcomes, providing insights for GDM management. Pregnant women diagnosed with GDM at a tertiary hospital in western China in 2019. Participants were categorized based on varying levels of glycemic control during pregnancy.
View Article and Find Full Text PDFInfluenza Infection During Pregnancy and Risk of Seizures in Offspring.
JAMA Netw Open
September 2024
Children's Medical Center, Taichung Veterans General Hospital, Taichung, Taiwan.
Article Synopsis
- - The study investigates the connection between maternal influenza infection during pregnancy and the likelihood of children experiencing seizures by analyzing a large dataset of mother-offspring pairs in Taiwan from 2004 to 2013.
- - Mothers with influenza were compared to a control group without the infection, matched on factors like age and delivery date, with follow-up data collected until 2020 to assess childhood seizure incidence.
- - Results indicated findings through adjusted hazard ratios suggest a potential association between maternal influenza during pregnancy and an increased risk of seizures in children, including epilepsy and febrile seizures.
Navigating the Complexities: A Rare Case of Intrahepatic Cholestasis of Pregnancy With Placenta Previa Manifesting With Seizures.
Cureus
August 2024
Obstetrics and Gynaecology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Intrahepatic cholestasis of pregnancy (ICP) is a prevalent and reversible liver disorder that occurs during pregnancy. It is primarily characterized by itching, especially on the palms and soles, and elevated levels of transaminases and bile acids. Some patients may also exhibit hyperbilirubinemia.
View Article and Find Full Text PDFRisk factor stratification for urgent and nonurgent transfusion in patients giving birth.
Am J Obstet Gynecol MFM
November 2024
The University of Utah Division of Maternal Fetal Medicine and Intermountain Health (Einerson), Salt Lake City, Utah, USA.
Article Synopsis
- A study aimed to determine how various risk factors during labor and delivery influence the need for blood transfusions, addressing gaps in existing protocols that don't accurately predict urgency of transfusion needs.
- The research reviewed medical records from nearly 90,000 patients across 18 hospitals over 40 months to identify those who required blood transfusions, particularly focusing on urgent cases.
- Findings included the calculation of odds ratios for needing transfusions based on risk factors, leading to the development of a formula to assess individual risk and optimize blood preparation before childbirth.
First- and Second-Trimester Aneuploidy Screening Biomarkers and Risk Assessment of Placenta Previa and Accreta: A Systematic Review and Meta-Analysis.
J Obstet Gynaecol Can
November 2024
High Risk Pregnancy Unit, First Department of Obstetrics and Gynecology, "Alexandra" Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Article Synopsis
- The study examines the differences in maternal serum biomarkers during the first and second trimesters for aneuploidy screening among women with placenta accreta spectrum (PAS), placenta previa, and normal pregnancies.
- A systematic review of data up to April 2023 included 8 retrospective studies with 1886 participants, revealing significant variations in biomarker levels, such as higher pregnancy-associated plasma protein-A in PAS patients during the first trimester.
- The findings highlight the potential for developing early screening methods for placental disorders, but emphasize the need for further large-scale studies to validate these results.
Low placenta at the mid trimester anomaly scan-A cause for concern?
J Clin Ultrasound
September 2024
Department of Fetal Medicine, Fernandez Hospital, Hyderabad, India.
Objective: This study was aimed to assess the predictive validity of internal os distance (IOD) in mid-trimester scan for the prediction of third-trimester low-positioned placenta, and to define a cut-off of IOD at which third-trimester low-positioned placenta could be identified, see the association of placental site (anterior/posterior), previous history of cesarean section with abnormal location of placenta in third trimester and see the maternal and neonatal outcomes.
Methods: It was a prospective cohort study of women with low-positioned placenta (IOD < 20 mm) at mid-trimester anomaly scan followed up in third trimester till birth. Relative risks for a low-positioned placenta in the third-trimester were calculated for women with posterior versus anterior, low-lying placenta versus placenta previa and positive versus negative history of cesarean section.
Abnormal Placentation After Caesarean Section: A Retrospective Study.
Cureus
August 2024
Obstetrics and Gynaecology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pune, IND.
Introduction Caesarean section (CS) is a lifesaving operation; it can have many complications in subsequent pregnancies. Since the uterine wall and cavity are not normal after CS, the implantation and subsequent trophoblastic invasion and placenta formation may be affected. This study was carried out to find out implantation and placental problems encountered in subsequent pregnancies.
View Article and Find Full Text PDFPlacental T2-weighted MRI-based radiomics-clinical nomogram to predict postpartum hemorrhage of placenta previa.
Acta Radiol
November 2024
Department of Obstetrics and Gynecology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, Jiangsu, PR China.
Article Synopsis
- Placenta previa is a serious pregnancy complication that can lead to severe bleeding and is associated with high risks for mothers.
- This study aimed to assess how effective MRI-based radiomics analysis is in predicting postpartum hemorrhage for women with this condition.
- Using MRI data from 371 patients, researchers developed a predictive model that showed strong accuracy in forecasts, indicating that MRI can be a valuable tool for managing risks in pregnancies with placenta previa.
Obstetric outcomes in the expectant management of cesarean scar pregnancy with fetal heart activity: a single-center retrospective cohort study.
Quant Imaging Med Surg
September 2024
Department of Ultrasonography, West China Second University Hospital, Sichuan University, Chengdu, China.
Background: Cesarean scar pregnancy (CSP) is a high-risk complication characterized by the implantation of a pregnancy within a cesarean scar resulting from a previous delivery. Currently, clinical indicators guiding the expectant management of patients with CSP are lacking. We thus aimed to evaluate pregnancy and neonatal outcomes among women who underwent expectant CSP management and to investigate whether sonographic signs correlated with obstetric outcomes.
View Article and Find Full Text PDFDiffusion lacunae: a novel MR imaging finding on diffusion-weighted imaging for diagnosing placenta accreta spectrum.
Jpn J Radiol
September 2024
Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa, Japan.
Objective: To evaluate the usefulness of novel diffusion-weighted imaging (DWI) findings for diagnosing placenta accreta spectrum (PAS).
Materials And Methods: This retrospective study included 49 pregnant women with suspected PAS who underwent 1.5 T placental MRI.