5,442 results match your criteria: "Pituitary Disease and Pregnancy"
J Appl Lab Med
December 2024
Department of Pathology & Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO, United States.
Elevated human chorionic gonadotropin (hCG) of unknown etiology is often a diagnostic dilemma. Determination of its source is vital in order to provide proper medical treatment and prevent possible unneeded therapeutic interventions. The differential diagnosis for elevated hCG is broad and includes pregnancy, chronic kidney disease, heterophile antibody, macro-hCG, exogenous hCG administration, pituitary secretion, tumor-associated secretion, etc.
View Article and Find Full Text PDFSemin Reprod Med
September 2024
Department of Medicine, University of Rochester School of Medicine & Dentistry, Rochester, New York.
Hashimoto thyroiditis and Graves' disease are autoimmune thyroid disorders that are common in women of reproductive age and have a complex relationship with female fertility and health of the maternal-fetal dyad. Both hyperthyroidism and hypothyroidism, whether subclinical or overt in severity, directly or indirectly affect nearly every level of the hypothalamic-pituitary-ovary axis, uterine and ovarian function, as well as fetal development from implantation through delivery. Autoimmunity itself also appears to negatively impact both spontaneous and assisted fertility, as well as miscarriage risk, although the mechanism remains unclear, and the presence and magnitude of risk is variable in published literature.
View Article and Find Full Text PDFTransl Pediatr
November 2024
Department of Endocrinology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Background: The development of the testes is a tightly regulated process, requiring the coordination of multiple genes. Mutations in these genes can result in 46,XY gonadal dysgenesis. , located at Xp21, is a gene expressed in the developing adrenals, gonads, hypothalamus, and pituitary gland.
View Article and Find Full Text PDFStress Health
December 2024
Department of Psychology, University of California, Los Angeles, California, USA.
Clin Diabetes Endocrinol
November 2024
Republic of Iraq Ministry of Health, Karbala, Iraq.
Background: Type 2 diabetes mellitus (T2DM) is a multifaceted metabolic disorder. Over the past decade, the potential role of Growth Hormone (GH) and Insulin-like Growth Factor-1 (IGF-1) in the pathogenesis and progression of T2DM has garnered scientific interest. These hormones, while interrelated, exert differential effects on glucose homeostasis; GH elevates blood glucose levels, whereas IGF-1 sustains insulin secretion and augments insulin sensitivity.
View Article and Find Full Text PDFCureus
October 2024
Internal Medicine, Royal Preston Hospital, Preston, GBR.
Reproduction
November 2024
P Hannon, Department of Obstetrics and Gynecology , University of Kentucky, Lexington, United States.
Rev Assoc Med Bras (1992)
November 2024
University of Campinas, School of Medicine - Campinas (SP), Brazil.
J Endocr Soc
October 2024
Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg S-405 30, Sweden.
Context: Neurodevelopmental impairments are common among survivors of extremely preterm birth, particularly in males. Hyperactivation of the hypothalamic-pituitary-gonadal (HPG) axis has been suggested as an underlying cause, but this has been poorly investigated.
Objective: Establish levels and temporal changes in circulating androgens in extremely preterm infant males.
Environ Res
January 2025
School of Biodiversity, One Health and Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, UK.
Environmental chemicals (ECs) have been associated with a broad range of disorders and diseases. Daily exposure to various ECs in the environment, or real-life exposure, has raised significant public health concerns. Utilizing the biosolids-treated pasture (BTP) sheep model, this study demonstrates that in-utero exposure to a real-life EC mixture disrupts hypothalamo-pituitary-gonadal (HPG) axis gene expression and reproductive traits in prepubertal (8-week-old, 8w) and adult (11-month-old) male sheep.
View Article and Find Full Text PDFPharmacol Biochem Behav
December 2024
Department of Psychiatry, Renmin Hospital of Wuhan University, Jiefang Road No.238, Wuhan 430060, China. Electronic address:
Background: Pregnancy is a very complex and highly stressful time in women. Despite the high prevalence of postpartum depression, more than 50 % of mothers are undiagnosed or untreated, showing an urgent need to explore an effective preventive strategy. Regular physical activity has been suggested to be associated with an increased quality of life in pregnant and postpartum women.
View Article and Find Full Text PDFMed Sci (Basel)
September 2024
Department of Endocrinology, Diabetes and Metabolism, Elena Venizelou Hospital, GR-11521 Athens, Greece.
J Med Case Rep
October 2024
Department of Endocrinology, Monash Health, 246 Clayton Road, Clayton, VIC, Australia.
Background: Bilateral adrenal hemorrhage is a rare but often a fatal cause of primary adrenal insufficiency that can result in adrenal crisis if not identified and managed appropriately.
Case Presentation: We present a case of a 27-year-old Caucasian female who was admitted to the hospital 17 days postpartum with pleuritic chest and flank pain, shortness of breath and nausea. Computed tomography imaging confirmed multiple thromboemboli including pulmonary emboli and noted bilateral bulky adrenal glands.
J Psychosom Obstet Gynaecol
December 2024
Assisted Reproduction Unit, Department of Gynecology and Obstetrics, Sir Run Run Shaw Hospital, Hangzhou, China.
This narrative review explores the relationship between psychological stress and ovulatory disorders, focusing on the molecular mechanisms involved. Ovulation is regulated by the hypothalamus-pituitary-ovarian (HPO) axis, and disruptions in this axis can lead to ovulatory dysfunction. Chronic psychological stress affects the HPO axis, resulting in abnormalities in hypothalamus hormone secretion, pituitary hormone release, and ovarian function.
View Article and Find Full Text PDFClin Endocrinol (Oxf)
October 2024
Department of Medicine, Division of Endocrinology, McMaster University, Hamilton, Ontario, Canada.
Context: Treating overt hyperthyroidism prevents atrial fibrillation (AF). Though subclinical hyperthyroidism (SH) has been associated with AF, it is unknown whether treating SH prevents AF.
Objective: We aimed to identify the association between treating SH and incident AF.
Endocrine
October 2024
Department of Endocrinology and Metabolism, Adrenal center, West China Hospital, Sichuan University, Chengdu, China.
Front Endocrinol (Lausanne)
October 2024
Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland.
Neoreviews
October 2024
Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
Folia Med Cracov
September 2024
Department of Pathophysiology, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland.
Probl Endokrinol (Mosk)
September 2024
Autoimmune/lymphocytic hypophysitis is one of the rare causes of central diabetes insipidus in adults and is most common among women in the second or third trimester of pregnancy. Numerous studies have shown that lymphocytic hypophysitis is characterized by a very variable clinical signs with the development of neurological symptoms, visual disturbances and hypopituitarism with partial or complete loss of pituitary function, as well as a number of features in magnetic resonance imaging (MRI). Isolated lymphocytic indibuloneurohypophysitis occurs in fewer cases and involves the posterior lobe and stalk of the pituitary gland with a clinical presentation of diabetes insipidus.
View Article and Find Full Text PDFJ Nephrol
September 2024
Néphrologie et Dialyse, Centre Hospitalier Le Mans, 194 Avenue Rubullard, 72037, Le Mans, France.
Contraception, pregnancy and fertility are seldom discussed with women receiving dialysis and the medical staff of dialysis centres. Since the majority of women on dialysis are past childbearing age, these themes are not always given proper consideration and this category of patients may be missing important information. Young women of childbearing age who are on dialysis frequently experience sexual dysfunction and hormonal disorders of the hypothalamic-pituitary-gonadal axis.
View Article and Find Full Text PDFAuris Nasus Larynx
September 2024
Department of Otolaryngology-Head & Neck Surgery, Kobe University, Graduate School of Medicine, Hyogo, Japan. Electronic address:
Endolymphatic hydrops, a pathological feature of Ménière's disease, has been experimentally and clinically confirmed to be influenced by the blood circulation of vasopressin (VP). VP is a well-known hormonal regulator of water homeostasis. In addition, VP is influenced by various environmental changes, dehydration, fluctuation of atmospheric pressure, pregnancy, and other factors.
View Article and Find Full Text PDFSci Total Environ
November 2024
Key Laboratory of the Public Health Safety, Ministry of Education, Department of Environmental Health, School of Public Health, Fudan University, Shanghai 200032, China; Key Laboratory of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai 200032, China; Center for Water and Health, School of Public Health, Fudan University, Shanghai 200032, China. Electronic address:
A burgeoning body of epidemiological and toxicological evidence suggests that thyroid health may be significantly impacted by exposure to both long- and short-chain perfluoroalkyl substances (PFAS) compounds. We conducted a meta-analysis to examine the association between 16 PFAS compounds and five thyroid hormones (TSH, TT3, TT4, FT3, and FT4) in the serum of a pregnant women, adolescents, and adults. The dose-response relationship between some PFAS and thyroid hormones in different population subpopulation was found and the model was fitted.
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