105 results match your criteria: "Pitted Keratolysis"

Gram-Negative Toe Web Infections.

Dermatol Pract Concept

January 2024

Department of Dermatology, Weill Cornell Medicine, New York, NY, USA.

Article Synopsis
  • Gram-negative bacterial toe web infection (GNTWI) is a skin condition that generally occurs in the spaces between toes, ranging from mild redness to severe infections that can spread to the foot.
  • Pseudomonas aeruginosa is the most commonly responsible bacterium, and certain conditions like moisture and existing skin issues can increase the risk of infection.
  • Diagnosis involves cultures to identify the bacteria or fungi, but treatment isn't standardized, and GNTWI may often be overlooked by healthcare professionals due to limited research on the topic.
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  • A study examined the cost-effectiveness and safety of combining 4% chlorhexidine scrub with ZnO-nanoparticle-coated socks for treating pitted keratolysis (PK) in male participants.
  • Although the combination treatment showed the best but nonsignificant improvement in foot odor, all treatments led to clinical improvement.
  • Cost-analysis indicated that the 4% chlorhexidine scrub was the most affordable option, making it the best choice for PK treatment compared to other therapies.
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Pitted keratolysis.

Clin Exp Dermatol

August 2023

Department of Dermatology, Venereology and Leprosy, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India.

Article Synopsis
  • Pitted keratolysis (PK) is a bacterial skin infection that affects the top layer of the skin, primarily seen on weight-bearing areas of the feet, resulting in small, crater-like lesions.
  • PK is usually asymptomatic but can cause bad odor and the affected skin may appear wet and softened.
  • Diagnosis is typically made through clinical observation, and treatment mainly involves lifestyle changes and topical antimicrobial medications.
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Pitted keratolysis.

Pan Afr Med J

July 2022

Department of Community Medicine, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education and Research Institute, Chennai, Tamil Nadu, India.

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Article Synopsis
  • Pitted keratolysis (PK) is a bacterial skin infection affecting the soles of the feet, leading to discomfort, and traditional antibiotic treatments face challenges due to resistance.
  • In a study comparing the antibacterial properties of essential oils (EOs), lemongrass emerged as the most effective against the bacteria causing PK, prompting further exploration.
  • Analysis identified 17 compounds in lemongrass, with α-terpineol showing strong antimicrobial activity, suggesting EO-based formulations could be promising alternatives for treating PK.
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Article Synopsis
  • Paddy farming in Kashmir exposes workers to irritants like fertilizers and pesticides, along with prolonged sun exposure, potentially leading to skin diseases.
  • A study of 600 paddy workers revealed that 38.3% had skin lesions, with non-infectious disorders being more prevalent than infectious ones.
  • The findings indicate a significant occurrence of skin disorders among paddy farmers, highlighting the occupational risks associated with the profession.
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Multiple malodorous pitted craters over the feet: Pitted keratolysis.

Paediatr Child Health

November 2021

Department of Paediatrics, Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.

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Article Synopsis
  • Pitted keratolysis (PK) is a bacterial skin infection typically diagnosed through clinical symptoms, but there is limited information on its dermoscopic and histopathological features.
  • A study involving 40 cadets with PK and 5 with healthy feet utilized dermoscopy and shave biopsies to examine the condition's clinical, dermoscopic, and histopathological characteristics.
  • Key findings revealed that dermoscopy was more effective than visual exams in detecting PK, with common signs including pits and bacterial presence, while color changes in keratin were noted in histopathology; both the presence of bacteria and certain changes correlated with poorer treatment outcomes.
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Article Synopsis
  • A study was conducted to evaluate the effectiveness of zinc oxide nanoparticles (ZnO-NPs) coated socks in preventing pitted keratolysis (PK) and bromodosis among military personnel, as these conditions negatively affect their quality of life.
  • The trial involved 148 naval cadets over a 14-day field training course, where participants were randomly assigned to wear either ZnO-NP-coated socks or regular uncoated socks, with assessments made on foot health and odor levels.
  • Results showed that cadets wearing ZnO-NP-coated socks had significantly less PK development and experienced less negative impact on daily life due to foot odor compared to those wearing uncoated socks.
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Pool Toes: Case Report and Review of Pool-Associated Pedal Dermatoses.

Cureus

November 2020

Dermatology, San Diego Family Dermatology, National City, USA.

Article Synopsis
  • Pool swimmers can develop various skin conditions on their feet, collectively known as pedal dermatoses, which can be caused by multiple factors such as friction, infections, and contact with pool surfaces.
  • Specific types of dermatoses include aquagenic keratoderma, pool dermatitis, and tinea pedis among others, which can lead to issues like blisters, itching, and skin irritation.
  • A case study highlights a seven-year-old girl who experienced pool toes, resulting in painful skin lesions on her feet after contact with a rough swimming pool surface, illustrating the impact of friction-induced injuries.
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Pitted Keratolysis.

Indian Pediatr

September 2020

Department of Dermatology, Venereology, and Leprosy, RG Kar Medical College, Kolkata, West Bengal, India.

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The foot microbiome.

J Cosmet Dermatol

May 2020

Department of Cosmetology, School of Pharmaceutical Science in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland.

Article Synopsis
  • * The feet have distinct microbial communities influenced by factors like skin thickness, sweat gland distribution, pH, and oxygen availability.
  • * Disorders in the foot microbiome can result in conditions such as pitted keratolysis, fungal and viral infections, and protothecosis.
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Article Synopsis
  • Treating skin disorders, especially on the feet, can be tough for river runners in the Grand Canyon due to the unique wilderness conditions.
  • The term "tolio" is commonly used to refer to various skin issues encountered by river runners, with pitted keratolysis being the most common.
  • A case study highlights a river guide suffering from pitted keratolysis during a multi-day trip, emphasizing the importance of prevention over treatment.
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Article Synopsis
  • A study was conducted to compare the effectiveness and safety of 2.5% and 5% benzoyl peroxide (BP) gel in treating pitted keratolysis (PK) among naval cadets in Thailand.
  • Results showed significant improvements in foot odor and pitted lesions for both concentrations, but the difference in effectiveness was not statistically significant.
  • The findings suggest that 2.5% BP is preferable due to similar outcomes but potentially lower side effects compared to 5% BP.
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Hyperhidrosis and its impact on those living with it.

Am J Manag Care

December 2018

Department of Dermatology, Emory University School of Medicine, Atlanta, GA. Email:

Article Synopsis
  • - Sweating is essential for humans, but excessive sweating, known as hyperhidrosis, occurs without external triggers, affecting about 4.8% of Americans, particularly those aged 18 to 39.
  • - Hyperhidrosis significantly impacts social, professional, mental, and emotional well-being, leading to a decreased quality of life for those affected.
  • - The condition also raises the risk of skin problems, with studies showing nearly a 30% higher chance of skin infections in hyperhidrosis patients compared to healthy individuals.
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Managing pitted keratolysis: consider topical glycopyrrolate.

Clin Exp Dermatol

August 2019

First Department of Dermatology-Venereology, National and Kapodistrian University of Athens, Faculty of Medicine, Andreas Sygros Hospital for Cutaneous and Venereal Diseases, 5 I. Dragoumi Street, GR-16121, Kaisariani, Athens, Greece.

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Article Synopsis
  • A study was conducted to evaluate the cost-effectiveness and safety of 4% chlorhexidine scrub compared to 4% erythromycin gel for treating Pitted keratolysis (PK) among naval cadets in Thailand.
  • 125 out of 344 cadets were diagnosed with PK, and after 4 weeks of treatment, both groups showed significant improvement in symptoms, with no reported adverse effects.
  • The total treatment costs were lower for chlorhexidine at $51.90 compared to $77.34 for erythromycin, and both treatments yielded similar quality-adjusted life-years (QALYs), but chlorhexidine was deemed more cost-effective.
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Tatami Mats: A Source of Pitted Keratolysis in a Martial Arts Athlete?

Acta Dermatovenerol Croat

April 2018

Daniela Ledić Drvar, MD, PhD, University Hospital Centre Zagreb, Department of Dermatology and Venereology, School of Medicine University of Zagreb, Šalata 4, 10000 Zagreb, Croatia;

Article Synopsis
  • Pitted keratolysis (PK) is a bacterial skin infection that often presents with small, crater-like pits on the soles of the feet, typically unnoticed until associated odor and excessive sweating cause distress.
  • The condition is prevalent globally, particularly among individuals who sweat heavily or wear tight-fitting shoes, with misdiagnosis common as it can resemble other foot ailments like athlete's foot or warts.
  • A case study highlighted a 32-year-old male patient misdiagnosed with plantar warts, whose PK was confirmed through clinical signs, negative fungal tests, and his sweaty lifestyle, especially from training barefoot on mats.
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Pitted keratolysis - a study of various clinical manifestations.

Int J Dermatol

November 2017

Department of Dermatology, Venereology and Leprology, H.B.T. Medical College and Dr. R.N. Cooper Hospital, Mumbai, Maharashtra, India.

Article Synopsis
  • Pitted keratolysis (PK) is a bacterial skin infection characterized by noninflammatory pits, often underdiagnosed when it presents in atypical forms; this study aimed to assess a variety of clinical manifestations in PK patients.* -
  • The study examined 30 patients, predominantly females, with common symptoms of hyperhidrosis and malodour; key affected areas included the skin between toes, plantar skin, and in some cases, palms and nails, revealing unusual inflammatory responses and lesions.* -
  • Findings indicate that PK can manifest beyond conventional symptoms, involving additional skin areas and presenting with inflammation and pigmentation changes, highlighting the need for broader recognition of its clinical variations.*
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Article Synopsis
  • Palmoplantar dermatoses pose significant challenges in dermatological treatment, with existing studies lacking a thorough investigation into these specific conditions.
  • This study aimed to examine the demographics and frequency of conditions affecting the palms and soles, focusing on factors like age and gender distribution.
  • Conducted from 2011 to 2013, the study analyzed 300 patients, revealing a higher incidence among females (1.2:1 ratio) and identifying palmoplantar psoriasis as the most prevalent condition (20.7%), particularly affecting individuals aged 21-30.
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Article Synopsis
  • Hepatitis B virus (HBV) infection can lead to various liver diseases, ranging from asymptomatic states to severe conditions like cirrhosis and liver cancer, along with extrahepatic symptoms like skin issues and joint pain.
  • HBV can also cause kidney problems, primarily manifesting as membranous glomerulonephritis, with symptoms like swelling, edema, and urinary abnormalities such as proteinuria and hematuria.
  • Treatment involves antiviral medications like entecavir and tenofovir, which are effective against HBV, while immunosuppressive therapy alone is not recommended due to risks of exacerbating the infection.
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Article Synopsis
  • Coryneform skin infections, which include conditions like pitted keratolysis, erythrasma, and trichobacteriosis, are frequently encountered but lack comprehensive studies on their characteristics in India and globally.
  • A study involving 75 patients revealed that pitted keratolysis mostly affects males aged 31-40, particularly in water-contact situations, while erythrasma appears equally among genders, often linked to higher body mass index (BMI) and diabetes.
  • Key findings indicate hyperhidrosis (excessive sweating) as a common risk factor, with specific clinical features observed, such as yellow concretions in trichobacteriosis, underscoring the need for careful diagnosis and consideration of diabetes in erythrasma cases.
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