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Article Synopsis
- Scleroma, caused by Klebsiella pneumoniae, is a rare chronic disease affecting the upper respiratory tract, with unclear causes and numerous immune system disturbances.
- A study analyzed the local immunity in the oropharynx of 92 scleroma patients and 20 healthy individuals, measuring several immune factors in their oropharyngeal secretions.
- The results showed significant decreases in secretory and monomeric immunoglobulins in scleroma patients, indicating a deficiency in local immunity that may contribute to the chronic inflammation seen in the disease, suggesting a need for immune therapy in treatment.