Foam-based antibacterial hydrogel composed of carboxymethyl cellulose/polyvinyl alcohol/cerium oxide nanoparticles for potential wound dressing.

Foam-based wound dressing materials produced by dispersing gas phases in a polymeric material are soft, adapt to the body shape, and allow the absorption of wound exudate due to their porous structure. Most of these formulations are based on synthetic substances such as polyurethane. However, biopolymers have entered the field as a new player thanks to their biocompatible and sustainable nature.

Delivery of proapoptotic gene in Peptide-18-targeted Poly(2-oxazoline)-DOPE nanoliposomes for breast cancer models.

Breast cancer is one of the most common cancers and a significant cause of death in females worldwide. For effective breast cancer treatment, using systems with a promising delivery of anticancer agents is an important strategy. Peptide 18 (P18), a tumor-homing peptide, shows a high binding affinity toward breast cancer cells.

Understanding Career Adapt Abilities, Career Stress, Work Stress, Career Regret, Job Satisfaction Among Nursing Professionals.

Aim: This study aims to conduct a comprehensive analysis of the interrelationships among career stress, work stress, career regret, job satisfaction and career adapt abilities within the nursing profession.

Design: The research involved a sample of 576 nurses from ten urban hospitals, distributed across five distinct cities in Turkiye, between December 2023 and January 2024. The study employed regression models to systematically test hypotheses, providing nuanced insights into the complex dynamics of the variables under investigation.

Repetitive Rolling of Triptycene-Based Molecules on Cu Surfaces.

The metal surface-supported rotation of artificial molecular structures is technologically important for developing molecular-level devices. The key factors leading to the practical applications of these molecular machines on metal surfaces are the atomic-scale control of the rotation and the counterbalance of the temperature-driven instability of the molecules. In this work, we present a means by which triptycene-based molecular wheels can roll repetitively on a metal surface.

PEtOx-DOPE nanoliposomes functionalized with peptide 563 in targeted delivery to prostate cancer.

Background: Nanocarrier-based systems have cultivated significant improvements in prostate cancer therapy. However, the efforts are still limited in clinical applicability, and more research is required for the development of effective strategies. Here, we describe a novel nanoliposomal system for targeted apoptotic gene delivery to prostate cancer.

Investigation of Resistance Switching and Synaptic Properties of VO for Neuromorphic Applications.

The taking run on artificial intelligence in the last decades is based on the von Neumann architecture where memory and computation units are separately located from each other. This configuration causes a large amount of energy and time to be dissipated during data transfer between these two units, in contrast to synapses in biological neurons. A new paradigm has been proposed inspired by biological neurons in human brains, known as neuromorphic computing.

Polymer physics view of peripheral chromatin: de Gennes' self-similar carpet.

Using scaling arguments to model peripheral chromatin localized near the inner surface of the nuclear envelope (NE) as a flexible polymer chain, we discuss the structural properties of the peripheral chromatin composed of alternating lamin-associated domains (LADs) and inter-LADs. Modeling the attraction of LADs to NE by de Gennes' self-similar carpet, which treats the chromatin layer as a polymer fractal, explains two major experimental observations. (i) The high density of chromatin close to the nuclear periphery decays to a constant density as the distance to the periphery increases.

Design of Polymeric Nanoparticles for Theranostic Delivery of Capsaicin as Anti-Cancer Drug and Fluorescent Nitrogen-Doped Graphene Quantum Dots.

In recent years, multifunctional nanocarriers that provide simultaneous drug delivery and imaging have attracted enormous attention, especially in cancer treatment. In this research, a biocompatible fluorescent multifunctional nanocarrier is designed for the co-delivery of capsaicin (CPS) and nitrogen-doped graphene quantum dots (N-GQDs) using the pH sensitive amphiphilic block copolymer (poly(2-ethyl-2-oxazoline)-b-poly(ε-caprolactone), PEtOx-b-PCL). The effects of the critical formulation parameters (the amount of copolymer, the concentration of poly(vinyl alcohol) (PVA) as a stabilizing agent in the inner aqueous phase, and volume of the inner phase) are evaluated to achieve optimal nanoparticle (NP) properties using Central Composite Design.

A generalized Chebyshev operational method for Volterra integro-partial differential equations with weakly singular kernels.

Volterra integro-partial differential equations with weakly singular kernels (VIPDEWSK) are utilized to model diverse physical phenomena. A matrix collocation method is proposed for determining the approximate solution of this functional equation category. The method employs shifted Chebyshev polynomials of the fifth kind (SCPFK) to construct two-dimensional pseudo-operational matrices of integration, avoiding the need for explicit integration and thereby speeding up computations.

Discriminant analysis using MRI asymmetry indices and cognitive scores of women with temporal lobe epilepsy or schizophrenia.

Purpose: This study aims to assess the diagnostic power of brain asymmetry indices and neuropsychological tests for differentiating mesial temporal lobe epilepsy (MTLE) and schizophrenia (SCZ).

Methods: We studied a total of 39 women including 13 MTLE, 13 SCZ, and 13 healthy individuals (HC). A neuropsychological test battery (NPT) was administered and scored by an experienced neuropsychologist, and NeuroQuant (CorTechs Labs Inc.

Synthesis of Calamitic Fluorinated Mesogens with Complex Crystallization Behavior.

This work presents the synthesis and self-organization of the calamitic fluorinated mesogen, 1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoro-4-iodobutoxy)ethanesulfonic acid, a potential model for perfluorosulfonic acid membranes (PFSA). The compound is derived in three steps from 1,1,2,2-tetrafluoro-2-(1,1,2,2-tetrafluoro-2-iodoethoxy)ethanesulfonyl fluoride, achieving a 78% overall yield. The resulting compound exhibits intricate thermal behavior.

Implementation of a triangular probabilistic distribution for optimal parametrization of the SEIR model recovery rates with delay.

Dynamical analysis of epidemiological models received significant attention after the global disaster of the Covid-19 pandemic. Although much of the attention has focused on choosing the appropriate model to describe and interpret the epidemiological data and on predicting the spread of the disease, working on uncovering the hidden dynamics by analyzing the predictive data and studying the algebraic properties of the models such as the invariant spaces, the center manifolds, and the Lyapunov functions in the general parameter space still have the potential to make a significant contribution to our understanding of the dynamics of spread. In this paper, in order to determine the recovery rate based on characteristic model parameters, the triangular probabilistic distribution is implemented in an epidemic delay differential equation with delays.

Biochemical models of SIR and SIRS: Effects of bilinear incidence rate on infection-free and endemic states.

Understanding and forecasting the progression of disease epidemics is possible through the study of nonlinear epidemic biochemical models that describe the relationship among susceptible, infected, and immune individuals in a population. In this paper, by determining the algebraic invariant planes and studying the Hopf bifurcation on these invariant planes, we study the stability of the Hopf bifurcation in the infection-free and endemic states of the SIR and SIRS epidemic models with bilinear incidence rate. We analyze the stability of the limit cycles of the bilinear incidence SIR and SIRS models at the steady state point where infection vanishes and at the endemic steady state point where the system behaves in an oscillatory manner.

A Polycaprolactone-Capped ZnO Quantum Dots-Based Fluorometric Sensor for the Detection of Fe Ions in Seawater.

Fe ion plays a very active role in life, agriculture, and industry. Human health and the environment are seriously affected by the abnormal presence or excess of this cation. Therefore, the development of a fast, reliable, sensitive, and simple fluorescent probe to detect this cation is crucial.

Structural analysis and characterization of date palm fiber-based low-cost carbon nanotubes and nanostructured powder activated carbon.

The structural properties and characteristics of date palm fiber-based low-cost carbon nanotubes (CNTs) and nanostructured powder activated carbon (DP-NPAC) are investigated. The DP-NPAC and CNTs are prepared using an environmentally friendly method, and characterized and analyzed using field emission-scanning electron microscopy (FESEM), transmission electron microscopy (TEM), and X-ray diffraction (XRD). The results have showed that both DP-NPAC and CNTs possess crystallite structure, nano-scale, high capacity, cost-effective for multi-application that make them efficient for future fabrication and manufacturing.

Synthesis, Characterization, and DFT Calculations of a New Sulfamethoxazole Schiff Base and Its Metal Complexes.

A new Schiff base, 4-((1E,2E)-3-(furan-2-yl)allylidene)amino)-N-(5-methylisoxazol-3-yl) benzene-sulfonamide (L), was synthesized by thermal condensation of 3-(2-furyl)acrolein and sulfamethoxazole (SMX), and the furan Schiff base (L) was converted to a phenol Schiff base (L') according to the Diels-Alder [4 + 2] cycloaddition reaction and studied experimentally. The structural and spectroscopic properties of the Schiff base were also corroborated by utilizing density functional theory (DFT) calculations. Furthermore, a series of lanthanide and transition metal complexes of the Schiff base were synthesized from the nitrate salts of Gd, Sm, Nd, and Zn (L, L, L, and L), respectively.

Targeting prostate cancer with docetaxel-loaded peptide 563-conjugated PEtOx-co-PEI-b-PCL polymeric micelle nanocarriers.

Prostate cancer is a global disease that negatively affects the quality of life. Although various strategies against prostate cancer have been developed, only a few achieved tumor-specific targeting. Therefore, a special emphasis has been placed on the treatment of cancer using nano-carrier-encapsulated chemotherapeutic agents conjugated with tumor-homing peptides.

Comparative physical, antioxidant, and antimicrobial properties of films prepared by dissolving chitosan in bioactive vinegar varieties.

Solvent casting following the dissolution of chitosan in aqueous acetic acid is the most widely used method for preparing chitosan films. In this study, an economical and practical way is proposed to improve the physicochemical properties of chitosan films by using vinegar varieties both as solvents and as bioactive additives to improve the properties of the films. Chitosan films were prepared by dissolving chitosan in pomegranate, grape, apple, and hawthorn vinegar.

Understanding Covid-19 Mobility Through Human Capital: A Unified Causal Framework.

This paper seeks to identify the causal impact of educational human capital on social distancing behavior at workplace in Turkey using district-level data for the period of April 2020 - February 2021. We adopt a unified causal framework, predicated on domain knowledge, theory-justified constraints anda data-driven causal structure discovery using causal graphs. We answer our causal query by employing machine learning prediction algorithms; instrumental variables in the presence of latent confounding and Heckman's model in the presence of selection bias.

Effect of AISI H13 Steel Substrate Nitriding on AlCrN, ZrN, TiSiN, and TiCrN Multilayer PVD Coatings Wear and Friction Behaviors at a Different Temperature Level.

Moving components of industrial machines and tools are subjected to wear and friction. This reduces their useful life and efficiency in running conditions, particularly at high temperatures. One of the most popular solutions is to apply an appropriate surface coating to the tribocouple's base materials.

Detection of the separated root canal instrument on panoramic radiograph: a comparison of LSTM and CNN deep learning methods.

Objectives: A separated endodontic instrument is one of the challenging complications of root canal treatment. The purpose of this study was to compare two deep learning methods that are convolutional neural network (CNN) and long short-term memory (LSTM) to detect the separated endodontic instruments on dental radiographs.

Methods: Panoramic radiographs from the hospital archive were retrospectively evaluated by two dentists.

Fabrication and Application of Halloysite Nanotube-Embedded Photocatalytic Nanofibers with Antibacterial Properties.

With decreasing indoor air quality, increased time spent at indoors, and especially with the COVID-19 pandemic, the development of new materials for bacteria and viruses has become even more important. Less material consumption due to the electrospinning process, the easy availability/affordability of the halloysite nanotube (HNT), and the antibacterial effect of both TiO and ZnO nanoparticles make the study even more interesting. HNTs have attracted research attention in recent years due to their low cost, high mechanical strength, natural and environmentally friendly structure, and non-toxicity to human health and ecosystem.