603 results match your criteria: "Phramongkutklao College of Medicine[Affiliation]"
Comput Biol Med
December 2024
Center for Lightweight Materials, Design, and Manufacturing, Department of Mechanical Engineering, Faculty of Engineering, King Mongkut's University of Technology Thonburi (KMUTT), Bangmod, Bangkok, 10140, Thailand; OsseoLabs Co. Ltd., Bangkok, 10400, Thailand. Electronic address:
Sacral chordoma, an invasive tumor, necessitates surgical removal of the tumor and the affected region of the sacrum, disrupting the spinopelvic connection. Conventional reconstruction methods, relying on rod and screw systems, often face challenges such as rod failure, sub-optimal stability, and limited osseointegration. This study proposes a novel design for a porous-based sacral reconstruction prosthesis.
View Article and Find Full Text PDFPLoS Negl Trop Dis
December 2024
Department of Genetics, Faculty of Science, Kasetsart University, Bangkok, Thailand.
J Histochem Cytochem
December 2024
Department of Pathology, Phramongkutklao College of Medicine, Bangkok, Thailand.
Hematoxylin and eosin (H&E)-stained slides inevitably deteriorate over time, frequently becoming unreadable. Reutilizing these slides can reduce the need for additional serial sections, particularly when the target region is no longer available in the tissue block. This study aims to develop efficient protocols for recycling faded H&E-stained slides, providing benefits for future research on stored samples.
View Article and Find Full Text PDFInt Ophthalmol
November 2024
Department of Ophthalmology, Phramongkutklao Hospital, 315 Ratchawithi Road, Thung Phayathai Subdistrict, Ratchathewi, Bangkok, 10400, Thailand.
Purpose: To assess the clinical characteristics, progression patterns, and treatment outcomes of microbiologically confirmed microsporidial keratoconjunctivitis (MKC).
Methods: This prospective cross-sectional study included patients with superficial punctate epithelial keratitis clinically suspected of MKC. Comprehensive slit-lamp examinations were conducted, and corneal scraping was performed for Gram-chromotrope staining and polymerase chain reaction (PCR) analysis.
Orphanet J Rare Dis
November 2024
Department of Pediatrics, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Background: Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare subtype of non-Hodgkin lymphoma associated with hemophagocytic lymphohistiocytosis (HLH)/HLH-like systemic illnesses and germline HAVCR2 mutations. Although previous studies suggested successful treatment of SPTCL with immunosuppressive therapy (IST) without chemotherapy, IST data in pediatric SPTCL remain scarce. To explore characteristics and therapeutic outcomes, comparing IST-based and chemotherapy-based regimens in pediatric SPTCL, in this retrospective cohort study, patients with SPTCL diagnosed at age ≤20 years during 2007-2023 were enrolled from 6 hematology/oncology centers in Thailand.
View Article and Find Full Text PDFAnn Hematol
November 2024
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
The Thai Pediatric Oncology Group (ThaiPOG) has adapted treatment regimens from the Children's Oncology Group (COG) to enhance outcomes for childhood acute lymphoblastic leukemia (ALL). This study examined the risk factors and treatment results of pediatric ALL in Thailand. This multicenter study included newly diagnosed children (< 18 years) with ALL in 19 centers between January 1, 2015, and December 31, 2019.
View Article and Find Full Text PDFJ Eval Clin Pract
February 2025
Department of Health Sciences, College of Health Sciences, Columbia, Missouri, USA.
Objectives: This feasibility study evaluated the effectiveness of Support-Engage-Empower-Diabetes (SEE-Diabetes), a patient-centered educational tool designed to promote shared decision-making of diabetes management in older adults. We aimed to assess SEE-Diabetes's ability to facilitate patient engagement and collaborative goal setting, as measured by the Observational Patient Involvement (OPTION) scale and Shared Decision-Making Questionnaire (SDM-Q-Doc). We hypothesized that these instruments would effectively differentiate between healthcare providers who actively leveraged SEE-Diabetes to guide patient-centric conversations and set goals compared to those who did not.
View Article and Find Full Text PDFBr J Haematol
October 2024
Division of Hematology and Oncology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Haemoglobin (Hb) H disease and HbH disease with co-inherited HbE mutation are the most prevalent forms of α-thalassaemia in Southeast Asia. Data were limited when comparing clinical phenotypes between these two patient groups. We conducted a Thai multicentre study and enrolled 588 patients [median (IQR) age 13.
View Article and Find Full Text PDFInt J Pediatr
October 2024
Division of Allergy and Immunology, Department of Pediatrics, Phramongkutklao Hospital and Phramongkutklao College of Medicine, 315 Rajavithi Road, Ratchathewi, Bangkok 10400, Thailand.
Food allergy affects 1%-10% of children under five worldwide, with genetic and early-life factors playing a primary role. Reported factors include a family history of allergic diseases, personal atopic dermatitis, cesarean section, dietary restrictions during pregnancy and lactation, and the timing of introducing solid foods. This study was aimed at identifying various factors associated with food allergy and evaluate each food allergy's clinical features.
View Article and Find Full Text PDFInt J Med Educ
October 2024
Division of Hematology-Oncology, Department of Pediatrics, Phramongkutklao College of Medicine, Bangkok, Thailand.
Objectives: This study aimed to enhance the learning experience among medical students by empowering them to co-create learning tools and classroom activities.
Methods: A cross-sectional study was conducted with 10 participants from Year 2 of the new curriculum volunteering to participate in this study. Five were selected based on their diversities and empowered to design learning tools and class activities.
Asian Pac J Allergy Immunol
September 2024
Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Chulalongkorn University; and the King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
Background: Previous house dust mite subcutaneous immunotherapy (HDM SCIT) placebo-controlled trials have small sample sizes and lack a consensus on baseline treatment.
Objective: To determine the efficacy of HDM SCIT in moderate-to-severe allergic rhinitis (AR) patients treated with an intranasal corticosteroid at baseline.
Methods: We conducted a randomized, placebo-controlled trial comparing HDM SCIT against placebo in Dermatophagoides pteronyssinus (Der p) sensitized.
BMC Pregnancy Childbirth
October 2024
Department of Obstetrics and Gynecology, Chumphon Khet Udomsakdi Hospital and Clinical Medical Education Center, Chumphon, Thailand.
PLoS Negl Trop Dis
October 2024
Department of Parasitology, Phramongkutklao College of Medicine, Bangkok, Thailand.
Mol Imaging Radionucl Ther
October 2024
Chulalongkorn University Faculty of Medicine, King Chulalongkorn Memorial Hospital, Department of Radiology, Diagnostic Radiology Unit, Bangkok, Thailand.
A man in his 30s awaiting end-of-treatment F-fluorodeoxyglucose positron emission tomography/CT (F-FDG PET/CT) for primary mediastinal B-cell lymphoma developed chest pain and pericardial effusion. His interim F-FDG PET/CT showed complete metabolic responses. His blood test revealed elevated levels of inflammatory markers, including C-reactive protein of 204.
View Article and Find Full Text PDFInt J STD AIDS
October 2024
Department of Internal Medicine, Phramongkutklao Hospitaland College of Medicine, Bangkok, Thailand.
Background: Tuberculosis (TB) among people living with HIV/AIDS (PLWHA) contributes substantially to morbidity and mortality, particularly in high TB burden countries. Our objective is to investigate the clinical characteristics and mortality rates associated with TB among adult PLWHA over a 10-year period at an urban HIV clinic situated in a high TB burden country.
Method: A retrospective cohort study was conducted in 2022.
Parasit Vectors
September 2024
Center of Excellence in Vector Biology and Vector-Borne Disease, Chulalongkorn University, Bangkok, Thailand.
Cureus
August 2024
Department of Hematology and Oncology, The Queen's Medical Center, Honolulu, USA.
Case Rep Neurol Med
September 2024
Division of Medical Genetics Department of Pediatrics Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok 10400, Thailand.
Rhabdomyolysis, an emergency medical condition linked to muscle necrosis and intracellular substances released into the bloodstream, significantly endangers military personnel in heat-stress conditions. Rhabdomyolysis can also be an initial presentation in inherited muscle disorders. This study reports a novel case of calpainopathy (LGMDR1) diagnosed in a 19-year-old male military cadet who initially presented with recurrent rhabdomyolysis during training, a rare presentation in LGMD patients.
View Article and Find Full Text PDFBMC Med Educ
August 2024
Department of Physiology, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.
Background: A physician's empathy level substantially impacts clinical competence, patient relationships, and treatment outcomes. Yet, understanding empathy trends from medical students to resident doctors within a single institution is limited. This study delves into empathy trends within a single-center academic setting and identifies factors associated with low empathy.
View Article and Find Full Text PDFPLoS One
August 2024
Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Leishmaniasis, a neglected tropical disease caused by parasitic protozoa of the Leishmania genus, remains a global health concern with significant morbidity and mortality. In Thailand, the rising incidence of autochthonous leishmaniasis cases involving Leishmania (Mundinia) martiniquensis and novel Leishmania (Mundinia) orientalis underscores the critical need for accurate diagnosis and effective control strategies. This study presents a sensitive and specific nucleic acid lateral flow immunoassay (NALFIA) that integrates a duplex PCR assay with a lateral flow device (LFD) strip format.
View Article and Find Full Text PDFPLOS Glob Public Health
August 2024
Department of Disease Control, Division of Epidemiology, Field Epidemiology Training Program, Ministry of Public Health, Nonthaburi, Thailand.
In order to monitor public health trends and identify disease outbreaks early, efficient and reliable notification and surveillance systems are essential. Nepal uses a 1-3-7 malaria surveillance approach. The Short Message System (SMS) -based system for timely notification has been established.
View Article and Find Full Text PDFPLoS Negl Trop Dis
August 2024
Department of Clinical Pathology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Dusit, Bangkok, Thailand.
Clin Genet
January 2025
Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Protein phosphatase 2 regulatory subunit B56δ related neurodevelopmental disorder (PPP2R5D-related NDD) is largely caused by de novo heterozygous missense PPP2R5D variants. We report medical characteristics, longitudinal adaptive functioning, and in-person neurological, motor, cognitive, and electroencephalogram (EEG) activity for PPP2R5D-related NDD. Forty-two individuals (median age 6 years, range = 0.
View Article and Find Full Text PDFBMC Pediatr
August 2024
Division of Hematology/Oncology, Department of Pediatrics, Phramongkutklao Hospital and Phramongkutklao College of Medicine, 315 Ratchawithi Rd. Ratchathewi, Bangkok, 10400, Thailand.
Background: Health-related quality of life (HRQOL) is a vital assessment to demonstrate the achievement in pediatric cancer care parallels that of medical treatment. The Pediatric Quality of Life Inventory (PedsQL) 3.0 Cancer Module in the Thai Version has become a standard tool to access the HRQOL among Thai children with cancer and their families.
View Article and Find Full Text PDFAm J Trop Med Hyg
October 2024
Department of Parasitology, Phramongkutklao College of Medicine, Bangkok, Thailand.
Leishmaniasis poses significant public health challenges in endemic regions. Understanding the prevalence of asymptomatic Leishmania infection and identifying risk factors among blood donors is crucial. This study addressed a knowledge gap by evaluating the prevalence of asymptomatic Leishmania infection and pinpointing associated risk factors among blood donors in an endemic area in Thailand and aimed to enhance blood donation safety protocols and reduce the risk of transfusion-transmitted Leishmania infection.
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