1,363 results match your criteria: "Pharyngitis Viral"

Introduction: Most paediatric upper respiratory infections are virally mediated and result in self-limiting reactive lymphadenopathy. In children younger than 5 years, retropharyngeal lymph nodes may give rise to deep neck space infections in this potential space. Retropharyngeal infections are rare after 5 years because lymph nodes undergo atrophy.

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[Epidemiological and etiological characteristics of herpes pharyngitis in 3 prefectures in Jiangsu Province].

Zhonghua Liu Xing Bing Xue Za Zhi

July 2024

Institute of Acute Infectious Disease Prevention and Control, Jiangsu Provincial Center for Disease Control and Prevention, Key Laboratory of Enteric Pathogenic Microorganisms, National Health Commission, Nanjing 210009, China.

Article Synopsis
  • The study examines the characteristics and data on herpes pharyngitis (HA) in three regions of Jiangsu Province over a four-year period to assist in its prevention and control.
  • A total of 57,709 HA cases were recorded, showing a significant increase compared to hand, foot, and mouth disease cases, with most infections occurring in young children aged 12-59 months.
  • Enterovirus A was identified as the primary cause, particularly Coxsackievirus A6, with genetic analysis revealing connections to strains from other areas in China.
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Acute Appendicitis in the Setting of Infectious Mononucleosis: A Case Report.

Cureus

June 2024

Department of Orthopaedics, Logan Regional Orthopedics, Intermountain Health, Logan, USA.

Article Synopsis
  • Infectious mononucleosis (IM) is a viral illness caused by the Epstein-Barr virus, often showing symptoms like sore throat, swollen lymph nodes, and fatigue.
  • The case discusses an 18-year-old girl who showed abdominal pain and cough; initial tests hinted at possible appendicitis, leading to further examinations revealing symptoms of IM.
  • Ultimately, her severe abdominal pain and positive monospot test resulted in her getting an appendectomy, highlighting the importance of detailed medical history and examination for identifying unusual causes in appendicitis cases.
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  • A study evaluated the effectiveness of a dietary supplement called PediaFlù, containing honey, propolis, and zinc, for treating children aged 3 to 10 with acute tonsillopharyngitis, comparing it to standard care alone.* -
  • The results showed that combining PediaFlù with standard care led to significant improvements in symptoms like throat pain and swallowing by days 4 and 6.* -
  • There were no adverse events reported, suggesting that PediaFlù could be a safe and effective addition to pediatric treatment for reducing unnecessary antibiotic use.*
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Invasive Streptococcal Infection in Children: An Italian Case Series.

Children (Basel)

May 2024

Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.

Article Synopsis
  • * A study conducted at a pediatric clinic analyzed data from children hospitalized for iGAS infections in 2023, revealing clinical patterns and groundbreaking insights into the infections.
  • * Between 2016 and 2023, the number of GAS infections remained relatively stable, but 2023 saw a significant increase in pediatric cases, with common symptoms including high fever, tachycardia, and vomiting; specific lab results were also noted.
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Article Synopsis
  • - Infectious mononucleosis (IM) is a viral illness mainly caused by the Epstein-Barr virus (EBV), commonly affecting teens and young adults, with symptoms like fever, swollen lymph nodes, and sore throat.
  • - A case study describes a 32-year-old woman who developed a rash after taking ibuprofen, which led to the discovery of her undiagnosed IM, confirmed by lab tests for EBV.
  • - This case is significant as it is the first to link NSAIDs with the presentation of IM symptoms, highlighting the importance of being aware of such associations for proper diagnosis and treatment, especially in patients with unexplained skin reactions to medications.
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  • The review focuses on current evidence for managing streptococcal pharyngitis in children and highlights the importance of distinguishing it from viral infections to prevent complications.
  • It discusses the challenges of diagnosing based solely on clinical features and mentions the creation of clinical scores for more accurate diagnosis, along with the mixed opinions on the use of microbiological tests.
  • While treatment guidelines agree on the type of antibiotics to use, there is ongoing debate about the ideal length of treatment, especially due to a recent rise in streptococcal infections.
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  • Rheumatic heart disease (RHD) is a preventable condition arising from group A strep infections, causing significant heart issues, especially in children and young adults in Sudan and similar countries.
  • In response to the WHO's 2018 call for improved management guidelines, Sudan's health authorities, with WHO support, updated protocols for diagnosing and treating acute rheumatic fever (ARF) and RHD using evidence from literature between 2000 and 2022.
  • The new guidelines feature simplified diagnostic algorithms for bacterial pharyngitis and ARF, emphasizing initial penicillin treatment at primary care and proposing echocardiography for more accurate diagnosis, though its broad adoption is currently unfeasible.
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  • A 21-year-old female presented with symptoms like fever, sore throat, swollen lymph nodes, and a widespread rash, alongside a history of depression and recent bipolar disorder treatment.
  • Lab tests indicated elevated liver enzymes, eosinophilia, and other inflammatory markers, leading to a liver biopsy that suggested drug-induced hepatitis.
  • The diagnosis of DRESS (drug reaction with eosinophilia and systemic symptoms) was confirmed, requiring immediate cessation of the suspected medication and treatment with high-dose corticosteroids for recovery.
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  • Group A Streptococcus (GAS) is a common cause of sore throats in children, but distinguishing it from viral infections can be tough, leading to unnecessary antibiotic use and potential side effects like allergies.* -
  • A study evaluated 54 children aged 2-17 with sore throats using a machine learning algorithm alongside standard testing methods to determine if they had GAS or viral pharyngitis.* -
  • The algorithm accurately identified 80.6% of GAS infections, suggesting it could be a helpful tool in diagnosing bacterial pharyngitis and guiding appropriate antibiotic treatment.*
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  • The study aimed to examine respiratory pathology in children aged 10-14, focusing on the inflammatory response and oxidative stress related to acute respiratory infections (ARI).
  • The research involved 111 school-aged children with various upper respiratory conditions, such as acute pharyngitis and bronchitis, and noted correlations between erythrocyte levels and inflammatory markers like IL-1 and TNF-α.
  • Findings indicated that optimized treatment significantly reduced levels of C-reactive protein (CRP) and gamma-interferon (γ-IFN), suggesting a positive impact on inflammatory response and metabolic adaptations in the affected children.
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Article Synopsis
  • * Clinical decision rules are recommended to determine the likelihood of infection, with key symptoms like fever and tonsillar exudate increasing suspicion; a negative rapid antigen test should lead to a throat culture in kids.
  • * Penicillin and amoxicillin are the primary antibiotics for treatment, while steroids are not advised; tonsillectomy is rarely suggested and only after numerous episodes within specific timeframes.
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Streptococcus pyogenes, Group A Streptococcus (GAS), is a human pathogen that causes a spectrum of diseases from mild to severe, including GAS pharyngitis, a common acute respiratory disease in developed countries. Although wastewater-based epidemiology (WBE) has been extensively used to monitor viral pathogens such as severe acute respiratory syndrome coronavirus 2, its applicability to S. pyogenes remains unexplored.

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Objectives: Fusobacterium necrophorum is a common cause of pharyngotonsillitis. However, no guidelines exist on when to diagnose or treat it. We aimed to investigate associations between clinical criteria and F.

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Background: Medical guidelines are an important basis for qualitative and cost-effective patient care. However, there is a lack of clinical recommendations in anthroposophic medicine (AM), an integrative medicine approach frequently practised in Europe. Acute tonsillitis, which includes tonsillopharyngitis, is a common childhood disease.

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Preadmission course and management of severe pediatric group A streptococcal infections during the 2022-2023 outbreak: a single-center experience.

Infection

August 2024

Division of Pediatric Infectious Disease, Department of Pediatrics, Bern University Hospital, Inselspital, University of Bern, CH-3010, Bern, Switzerland.

Purpose: The massive increase of infections with Group A Streptococcus (GAS) in 2022-2023 coincided in Switzerland with a change of the recommendations for the management of GAS pharyngitis. Therefore, the objective of the present study was to investigate whether the clinical manifestations and management before hospitalization for GAS infection differed in 2022-2023 compared with 2013-2022.

Methods: Retrospective study of GAS infections requiring hospitalization in patients below 16 years.

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Background: Indiscriminate use of antibiotics is a well-known reason for increasing antimicrobial resistance. Upper respiratory tract infection presents with similar symptoms and signs irrespective of its bacterial or viral causes and is either ignored or managed aggressively by the primary care physicians. The objective was to determine the relationship between upper respiratory tract infections and treatment-seeking behaviour in healthy individuals attending the OPD clinics of BBS Teaching Hospital with their sick family members.

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Monkeypox (Mpox): Evolution of Transmission and Comprehensive Review.

Indian J Dermatol

January 2024

From the Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, Delhi, India.

The human monkeypox (mpox) virus is an orthopox virus that can be transmitted to humans. Though the disease has been endemic in Africa, the recent mpox outbreak since May 2022. We attempted to examine differences between the endemic form of mpox and the current outbreak.

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Notifications of invasive group A streptococcal (iGAS) infections have significantly increased in many European Countries compared to the previous season. In Italy, there has been an increase in streptococcal pharyngitis and scarlet fever cases since January 2023, which sparked concerns about a GAS epidemic in the pediatric population. This rise may be ascribed to the GAS infection season that began earlier than usual (off-season outbreak) and the increase in the spread of respiratory viruses and viral coinfections that raised the risk of iGAS disease.

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Background: HPVs are considered to have high-oncogenic risk. These genotypes have been proven to have a causal link to cancers, in pediatric and youth patients, with high rates of HPV presence in the tonsillar tissues.

Objective: A prospective case-control research for determining HPV 6/11 genotypes in tonsillar specimens of children who underwent operations in the otolaryngology departments of the Medical City Complex, Baghdad, Iraq, for their non-oncologic palatine and pharyngeal tonsillar hypertrophies.

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Objectives: Outpatient health care facilities are essential for quickly diagnosing common infectious diseases such as bacterial and viral pharyngitis. The only form of pharyngitis requiring antibiotics is strep throat (ST); however, antibiotic prescription rates are much higher than ST prevalence, suggesting antibiotics are being inappropriately prescribed. Current rapid ST diagnostics may be contributing to this problem due to the low sensitivity and variable specificity of these tests.

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Article Synopsis
  • * The patient initially showed a suspected B-ALL diagnosis due to abnormal blood cell counts, but after close monitoring, he had a complete normalization of blood tests within about 46 days.
  • * Despite the spontaneous remission, the patient later relapsed with B-ALL, emphasizing the need for careful monitoring in similar cases as spontaneous remissions often lead to recurrence.
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Article Synopsis
  • The recent mpox outbreak was labeled an international public health emergency, prompting a study in a Buenos Aires hospital to better understand its characteristics.
  • A case series study focused on 10 patients aged 15 and older, revealing a mean age of 35; the majority were men, and most had a history of risky sexual behavior.
  • Key findings included that 70% of patients had pseudopustules, with complications such as local edema and proctitis; notably, only 2% of infections in Argentina were reported in women, highlighting a significant gender disparity in this outbreak.
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