Am J Respir Cell Mol Biol
January 2025
Rostock University Medical Center, Institute of Medical Microbiology, Virology and Hygiene, Rostock, Germany.
(Group A Streptococcus, GAS) is a human pathogen that causes local and systemic infections of the skin and mucous membranes. However, GAS is also found asymptomatically in the nasopharynx of infants. GAS infections, including pharyngitis and invasive pneumosepsis, pose significant public health concerns.
View Article and Find Full Text PDFBMC Prim Care
December 2024
Department of Endocrinology, University hospital Dubrava, Zagreb, Croatia, and School of Medicine, and University of Zagreb, Zagreb, Croatia.
Background: Acute respiratory tract infections are common in primary healthcare care settings and frequently result in antibiotic prescriptions, despite being primarily viral. There is scarcity of research examining impact of academic detailing (AD) intervention on prescribing practices for these infections in resource-constrained healthcare settings like southeastern Europe. Therefore aim of this study was to evaluate impact of AD intervention as an antimicrobial stewardship measure on antibiotic prescribing for acute respiratory tract infections in primary setting in Croatia which is located in southeastern Europe.
View Article and Find Full Text PDFInfect Control Hosp Epidemiol
December 2024
Department of Pediatrics, Children's Mercy Kansas City, Kansas City, MO, USA.
Objective: To determine whether differences exist in antibiotic prescribing for respiratory infections in pediatric urgent cares (PUCs) by patient race/ethnicity, insurance, and language.
Design: Multi-center cohort study.
Setting: Nine organizations (92 locations) from 22 states and Washington, DC.
Cureus
October 2024
Internal Medicine, Centro Hospitalar Universitário Cova da Beira, Covilhã, PRT.
Acute disseminated encephalomyelitis (ADEM) is a rare autoimmune demyelinating disorder of the central nervous system that can mimic other neurological diseases, such as multiple sclerosis. ADEM is thought to manifest in the presence of environmental triggers, namely viral or bacterial infections, with multiple simultaneous neurological deficits, frequently accompanied by encephalopathy. Here, we report the case of a 49-year-old female patient who presented in the emergency department with encephalopathy, right-side muscle weakness, dizziness, vertigo, ataxia, and postural imbalance, preceded by symptoms suggesting recent pharyngitis/sialadenitis three weeks prior.
View Article and Find Full Text PDFTrials
November 2024
Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Background: Group A streptococci (Strep A) orStreptococcus pyogenes is a major human pathogen causing an estimated 500,000 deaths worldwide each year. Disease can range from mild pharyngitis to more severe infections, such as necrotizing fasciitis, septicemia, and toxic shock syndrome. Untreated, Strep A infection can lead to the serious post streptococcal pathologies of rheumatic fever/rheumatic heart disease and post-streptococcal glomerulonephritis.
View Article and Find Full Text PDFVestn Otorinolaringol
November 2024
Pirogov Russian National Research Medical University, Moscow, Russia.
Objective: To compare the microbiota of the oropharynx in healthy children and children with acute tonsillitis and pharyngitis.
Material And Methods: The study included two groups of patients (139 people) aged from 1 year to 17 years inclusive. The main group consisted of children with acute tonsillitis and acute pharyngitis (111 patients, average age 7±4 years), the control group consisted of 28 healthy children (average age 7±6 years) without signs of upper respiratory tract infection.
Front Pharmacol
October 2024
Department of Clinical Pharmacy, Meizhou People's Hospital (Huangtang Hospital), Meizhou, Guangdong, China.
Objective: Sapropterin dihydrochloride is the first drug for the therapy of phenylketonuria, which is a rare disease that occurs one of 10,000-15,000 newborns. As a result, detailed and comprehensive reports on the safety of sapropterin in large, real-world populations are required. The purpose of this study is to undertake a complete analysis of sapropterin's adverse events (AEs) using the FDA Adverse Event Reporting System (FAERS) database.
View Article and Find Full Text PDFEur J Pediatr
November 2024
Institute of Clinical Medicine and Department of Pediatrics, University of Eastern Finland, Yliopistonranta 2, 70211, Kuopio, Finland.
Unlabelled: The Finnish Current Care Guideline recommends rapid antigen tests as the primary diagnostic tool for both adults and children with Centor score ≥ 3. We aimed to analyze the association of Centor score and rapid antigen test positivity of group A streptococcal pharyngitis (GAS) in Finnish children. We performed a retrospective single-center study from July 2019 to June 2022.
View Article and Find Full Text PDFJ Infect Dis
October 2024
Department of Pathology and Laboratory Medicine, Arkansas Children's Hospital, Little Rock, AR, USA.
Pharyngitis is an inflammatory condition of the pharynx and/or tonsils commonly seen in both children and adults. Viruses and bacteria represent the most common encountered etiologic agents-yeast/fungi and parasites are infrequently implicated. Some of these are predominantly observed in unique populations (eg, immunocompromised or unvaccinated individuals).
View Article and Find Full Text PDFJ Biophotonics
October 2024
Pediatric Ambulatory Community Clinic, Petah Tikva, Israel.
Indian J Otolaryngol Head Neck Surg
October 2024
Department of Otorhinolaryngology, CIMS, Lucknow, Uttar Pradesh India.
Pharyngitis is a disorder commonly reported in ENT OPDs. The most common cause of Pharyngitis in India is Group A streptococcus, with prevalence rates of 13% in children aged 5-15%. It can also be attributed to various other bacterial, viral and fungal agents.
View Article and Find Full Text PDFBMC Infect Dis
October 2024
Faculty of Medicine, Al-Quds University, Abu Dis, Palestine.
Folia Med (Plovdiv)
June 2024
Sofiamed University Hospital, St Kliment Ohridski University, Sofia, Bulgaria.
J Investig Med High Impact Case Rep
October 2024
St. Joseph's University Medical Center, Paterson, NJ, USA.
Perimyocarditis and myopericarditis are inflammatory conditions of the pericardium and myocardium, often of idiopathic or infectious etiology, with viral infections being the most common. Nonrheumatic streptococcal myopericarditis (NSM) is a rare condition that can mimic acute myocardial infarction. This case report presents a 22-year-old male with no prior medical history who developed NSM following a streptococcal pharyngitis infection.
View Article and Find Full Text PDFFront Microbiol
September 2024
Cancer Research Center, Jiangxi University of Chinese Medicine, Nanchang, China.
Case Rep Pediatr
September 2024
Division of Pediatric Nephrology The University of Texas Medical Branch, Galveston, TX, USA.
Curr Opin Infect Dis
December 2024
Tropical Diseases Research Group, Murdoch Children's Research Institute.
Natl Med J India
September 2024
Department of Paediatric Emergency Medicine, Erciyes University Faculty of Medicine, Kayseri, Turkey.
Background Membranous tonsillitis is one of the most common forms of acute tonsillitis in childhood. Although many different microorganisms may cause this disease, clinicians generally consider bacterial agents as a possible cause and prescribe a penicillin-group of antibiotic. This study aimed to determine the aetiology of membranous tonsillitis and prescribing errors.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2024
Department of Otorhinolaryngology, Anshan Central Hospital, Anshan 114000, China.
Photodiagnosis Photodyn Ther
October 2024
Institute of Physics of São Carlos, University of São Paulo, São Carlos, SP, Brazil; Biomedical Engineering, Texas A&M University, College Station, TX, USA.
Background: Pharyngotonsillitis (PT) is an inflammatory and infectious condition affecting the tonsils in the oropharynx, predominantly caused by a variety of viral, fungal, and bacterial pathogens, including Streptococcus pyogenes. With the increasing challenge of antibiotic resistance, alternative therapeutic approaches are needed.
Methods: This study explores the effectiveness and safety of Photodynamic Therapy (PDT) as a therapeutic approach for managing acute PT.
Front Nutr
August 2024
Department of Scientific Research and Teaching, Public Health Clinical Center of Chengdu, Chengdu, Sichuan, China.
Rev Med Liege
July 2024
Service de Chirurgie abdominale, Clinique André Renard, Herstal, Belgique.
Cureus
July 2024
Internal Medicine, Creighton University School of Medicine, Phoenix, USA.
Respiration
October 2024
Department of Otorhinolaryngology, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.
Introduction: Most paediatric upper respiratory infections are virally mediated and result in self-limiting reactive lymphadenopathy. In children younger than 5 years, retropharyngeal lymph nodes may give rise to deep neck space infections in this potential space. Retropharyngeal infections are rare after 5 years because lymph nodes undergo atrophy.
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