3 results match your criteria: "Pharmaceutical and Health Sciences Kanazawa University Kanazawa Ishikawa Japan.[Affiliation]"
Cystatin C-based eGFR predicts cardiovascular disease in patients with overweight/obesity and hyperglycemia.
Obes Sci Pract
February 2023
Article Synopsis
- The study investigated risk factors for cardiovascular disease (CVD) in overweight and obese patients, focusing on the interaction between obesity-related conditions and CVD development.
- Conducted with 318 eligible patients from the Japan Obesity and Metabolic Syndrome study, it found that lower cystatin C-based estimated glomerular filtration rate (eGFRcys) levels were significantly linked to CVD in patients with high fasting plasma glucose (HFPG).
- The research concluded that tracking eGFRcys levels might be a more reliable predictor of CVD in these patients compared to traditional measures like creatinine-based eGFR (eGFRcr).
The phenotypic changes in hematopoietic stem progenitor cells (HSPCs) with somatic mutations of malignancy-related genes in patients with acquired aplastic anemia (AA) are poorly understood. As our initial study showed increased CXCR4 expression on HLA allele-lacking (HLA[-]) HSPCs that solely support hematopoiesis in comparison to redundant HLA(+) HSPCs in AA patients, we screened the HSPCs of patients with various types of bone marrow (BM) failure to investigate their CXCR4 expression. In comparison to healthy individuals ( = 15, 12.
View Article and Find Full Text PDFEffect of β3-adrenergic receptor gene polymorphism and lifestyle on overweight Japanese rural residents: A cross-sectional study.
Obes Sci Pract
April 2022
Department of Hygiene and Public Health Faculty of Medicine Institute of Medical, Pharmaceutical and Health Sciences Kanazawa University Kanazawa Ishikawa Japan.
Objectives: The β3-adrenergic receptor () gene polymorphism has been implicated in obesity. Therefore, the contribution of Trp64Arg polymorphism to obesity-related indicators was investigated, taking into account the lifestyle-related factors in a Japanese rural population.
Methods: A total of 600 Japanese adults aged ≥40 years in a population-based cohort study were analyzed.