7 results match your criteria: "Pharmaceutical and Environmental Sciences of the University of Messina[Affiliation]"
Fish Shellfish Immunol
February 2024
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences of the University of Messina, Messina, Italy; Department of Ecosustainable Marine Biotechnology, Stazione Zoologica Anton Dohrn, Naples, Italy. Electronic address:
Siberian sturgeon (Acipenser baerii) fry often face environmental stressors that can compromise their immune system, rendering them susceptible to opportunistic pathogens in intensive aquaculture systems. In this study, we explored the innovative use of chitosan nanoparticles loaded with Mentha piperita essential oil (MPO/CNPs) as a dietary supplement to improve the growth and immune responses of A. baerii.
View Article and Find Full Text PDFEnviron Toxicol Pharmacol
June 2023
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences of the University of Messina, Messina, Italy. Electronic address:
The plastic accumulation and its degradation into microplastics is an environmental issue not only for their ubiquity, but also for the release of intrinsic chemicals, such as phthalates (PAEs), non-phthalate plasticizers (NPPs), and bisphenols (BPs), which may reach body organs and tissues, and act as endocrine disruptors. Monitoring plastic additives in biological matrices, such as blood, may help in deriving relationships between human exposure and health outcomes. In this work, the profile of PAEs, NPPs and BPs was determined in Sicilian women's blood with different ages (20-60 years) and interpreted by chemometrics.
View Article and Find Full Text PDFMolecules
March 2023
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d'Alcontres 31, 98166 Messina, Italy.
Idebenone (IDE), a synthetic short-chain analogue of coenzyme Q10, is a potent antioxidant able to prevent lipid peroxidation and stimulate nerve growth factor. Due to these properties, IDE could potentially be active towards cerebral disorders, but its poor water solubility limits its clinical application. Octanoyl-β-cyclodextrin is an amphiphilic cyclodextrin (ACyD8) bearing, on average, ten octanoyl substituents able to self-assemble in aqueous solutions, forming various typologies of supramolecular nanoassemblies.
View Article and Find Full Text PDFComp Biochem Physiol C Toxicol Pharmacol
November 2022
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences of the University of Messina, Messina, Italy. Electronic address:
Biomater Adv
September 2022
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, V.le F. Stagno d'Alcontres 31, 98166 Messina, Italy. Electronic address:
A novel star-shaped amphiphilic copolymer based on three poly(lactide)-block-poly(ethylene glycol) (PLA-PEG) terminal arms extending from a glycerol multifunctional core was newly synthesized and decorated with the tumor-targeting ligand cyclic-RGDyK peptide (Arg-Gly-Asp-D-Tyr-Lys) to be eventually formulated in polymeric micelles incorporating a suitable anticancer drug (i.e., Docetaxel, DTX; drug loading 16 %, encapsulation efficiency 69 %).
View Article and Find Full Text PDFNutrients
November 2020
Department of Chemical, Biological, Pharmaceutical and Environmental Science, University of Messina, Via Giovanni Palatucci, 98168 Messina, Italy.
Background: Almond kernels contain phytochemicals with positive health effects in relation to heart disease, diabetes and obesity. Several studies have previously highlighted that almond cell wall encapsulation during digestion and particle size are factors associated with these benefits. In the present study, we have characterized almond oleosomes, natural oil droplets abundant in plants, and we have investigated their integrity during simulated gastrointestinal digestion.
View Article and Find Full Text PDFInt J Mol Sci
October 2018
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, V.le F. Stagno d'Alcontres 31, 98166 Messina, Italy.
The paper reviews the network of cellular signaling pathways activated by Functional Graphene Nanomaterials (FGN) designed as a platform for multi-targeted therapy or scaffold in tissue engineering. Cells communicate with each other through a molecular device called signalosome. It is a transient co-cluster of signal transducers and transmembrane receptors activated following the binding of transmembrane receptors to extracellular signals.
View Article and Find Full Text PDF