273 results match your criteria: "Peter Boris Centre for Addictions Research.[Affiliation]"
Curr Top Behav Neurosci
November 2020
Peter Boris Centre for Addictions Research, McMaster University and St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
This chapter provides an overview over the behavioral economic index of impulsivity known as delay discounting. Specifically, delay discounting refers to an individual's preference for smaller immediate rewards over a larger delayed rewards. The more precipitously an individual discounts future rewards, the more impulsive they are considered to be.
View Article and Find Full Text PDFBehavioral economic demand for cannabis (i.e., relative reinforcing value) can be measured via marijuana purchase tasks (MPTs).
View Article and Find Full Text PDFExp Clin Psychopharmacol
December 2020
Peter Boris Centre for Addictions Research, McMaster University.
There is some evidence that cannabis use is associated with lower cognitive performance and symptoms of attention-deficit/hyperactivity disorder (ADHD), but the existing literature is relatively inconsistent, potentially due to small samples in previous studies. Using a dimensional design, the current study examined cannabis use severity and age of first cannabis use in relation to neurocognitive performance and ADHD symptoms in a large sample of community adults ( = 1,008, = 38.49, 56.
View Article and Find Full Text PDFAddict Biol
January 2021
Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA.
Addict Biol
January 2021
Department of Psychology, University of Georgia, Athens, Georgia, USA.
There is mixed evidence that individuals who use cannabis have reduced hippocampal and amygdalar gray matter volume, potentially because of small sample sizes and imprecise morphological characterization. New automated segmentation procedures have improved the measurement of these structures and allow better examination of their subfields, which have been linked to distinct aspects of memory and emotion. The current study applies this new segmentation procedure to the Human Connectome Project Young Adult dataset (N = 1080) to investigate associations of cannabis use with gray matter volume in the hippocampus and amygdala.
View Article and Find Full Text PDFJ Behav Addict
December 2019
Child Study Center, Yale University School of Medicine, New Haven, CT,USA.
Background And Aims: Spirituality is an important component of 12-step programs for behavioral and substance addictions and has been linked to recovery processes. Understanding the neural correlates of spiritual experiences may help to promote efforts to enhance recovery processes in behavioral addictions. We recently used general linear model (GLM) analyses of functional magnetic resonance imaging data to examine neural correlates of spiritual experiences, with findings implicating cortical and subcortical brain regions.
View Article and Find Full Text PDFProg Neuropsychopharmacol Biol Psychiatry
April 2020
Departments of Psychiatry, Neuroscience and Child Study, Yale University School of Medicine, New Haven, CT, USA; Connecticut Council on Problem Gambling, Wethersfield, CT, USA; Connecticut Mental Health Center, New Haven, CT, USA.
Both psychological and neurobiological studies in gambling disorder have increased in the past 10-15 years. This review examines the current state of the literature, with a focus on recent magnetic resonance imaging (MRI) studies in gambling disorder. The review compares and contrasts findings across gambling and substance-use disorders.
View Article and Find Full Text PDFJAMA Psychiatry
March 2020
Peter Boris Centre for Addictions Research, St Joseph's Healthcare Hamilton, McMaster University, Hamilton, Ontario, Canada.
Neuroimage Clin
September 2020
Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, Ontario, Canada; Peter Boris Centre for Addictions Research, McMaster University & St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada. Electronic address:
Background: Although nutritional and metabolic factors are well established in obesity, neurocognitive determinants are less understood. Using data from the Human Connectome Project, this study concurrently investigated neurocognitive performance, neural activation during a working memory task, and cortical brain morphometry in relation to obesity in a group of young adults, 22-35 years old.
Methods: Using a case-control design, obese individuals (n = 243, body mass index [BMI] ≥ 30 kg/m) were compared to a control group of lean BMI individuals (n = 469, BMI = 18-24.
Sci Rep
November 2019
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, United States of America.
We investigated the association between impulsivity related traits and BMI at the observational and genetic epidemiology level in a cross-sectional population of healthy young American-European adults. We studied 998 students and university staff of European ancestry recruited from Chicago (Illinois) and Athens (Georgia). We measured 14 impulsivity variables using three broad categories: impulsive choice, action and personality.
View Article and Find Full Text PDFAlcohol Clin Exp Res
January 2020
Peter Boris Centre for Addictions Research, McMaster University/St Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
Drug Alcohol Depend
November 2019
Department of Health Research Methods, Evidence, and Impact, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4S4, Canada; Michael G. DeGroote Centre for Medicinal Cannabis Research, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4S4, Canada; Department of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West, Hamilton, Ontario, L8S 4S4, Canada. Electronic address:
Purpose: This systematic review summarizes and critically appraises the existing literature on brief interventions (BIs) for cannabis use among emerging adults.
Methods: Eligible BIs were operationalized as 1-2 sessions focused exclusively on cannabis use for samples with mean ages between 15 and 30. Outcomes related to cannabis use, other substance use, mental health, help-seeking, or functional status were included.
Adolesc Health Med Ther
August 2019
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
Background: The obesity and Type 2 Diabetes Mellitus (T2DM) rates are at an all-time high globally. This diabesity epidemic is increasingly impacting children and adolescents, and there is scarce evidence of interventions with favourable long-term outcomes.
Purpose: In order to understand the determinants of diabesity and how to address them, multiple stakeholders were invited to a meeting to discuss current state of knowledge and to help design a program to prevent pediatric and adolescent diabesity.
Curr Opin Psychiatry
January 2020
Department of Psychiatry and Behavioural Neurosciences, McMaster University MacAnxiety Research Centre, McMaster University MacAnxiety Research Centre, McMaster University Michael G. DeGroote Centre for Medicinal Cannabis Research Peter Boris Centre for Addictions Research, McMaster University & St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
Purpose Of Review: Cannabis use for medical purposes has become increasingly common, including as treatment for mental health disorders such as anxiety. Unfortunately, the evidence examining its use in mental health has been slow to evolve, but is emerging. Given the widespread use of cannabis, it is important for both clinicians and those who suffer with anxiety to understand the effects of cannabis on symptoms of anxiety.
View Article and Find Full Text PDFAddiction
May 2020
Department of Psychology, The University of Memphis, Memphis, TN, USA.
Background And Aims: Reinforcing value, an index of motivation for a drug, is commonly measured using behavioral economic purchase tasks. State-oriented purchase tasks are sensitive to phasic manipulations, but with heterogeneous methods and findings. The aim of this meta-analysis was to characterize the literature examining manipulations of reinforcing value, as measured by purchase tasks and multiple-choice procedures, to inform etiological models and treatment approaches METHODS: A random-effects meta-analysis of published findings in peer-reviewed articles.
View Article and Find Full Text PDFExcessive delayed reward discounting (DD) is observed across many addictive disorders. However, research on DD among cannabis users is limited, with even less research on discounting of cannabis rewards. This study examined monetary and cannabis reward discounting among cannabis and noncannabis users.
View Article and Find Full Text PDFThe Cigarette Purchase Task (CPT) affords a high-resolution index of the reinforcing efficacy of nicotine. Although a high number and steep progression of prices have traditionally been used, attention is now placed on developing brief measures of this task. This study sought to assess the psychometric properties of a brief CPT for assessing cigarette demand in treatment-seeking smokers with and without depressive symptoms.
View Article and Find Full Text PDFSyst Rev
September 2019
Department of Psychology, Neuroscience and Behaviour, McMaster University, Hamilton, Ontario, Canada.
Background: Heavy episodic drinking (HED) refers to alcohol consumption that exceeds the recommended threshold for a given episode and increases risk for diverse negative alcohol-related consequences. A pattern of weekly HED is most prevalent in emerging adults (i.e.
View Article and Find Full Text PDFJAMA Psychiatry
November 2019
Peter Boris Centre for Addictions Research, St Joseph's Healthcare Hamilton, McMaster University, Hamilton, Ontario, Canada.
Importance: Delay discounting is a behavioral economic index of impulsive preferences for smaller-immediate or larger-delayed rewards that is argued to be a transdiagnostic process across health conditions. Studies suggest some psychiatric disorders are associated with differences in discounting compared with controls, but null findings have also been reported.
Objective: To conduct a meta-analysis of the published literature on delay discounting in people with psychiatric disorders.
Front Neurosci
August 2019
Gender Identity Program (PROTIG), Psychiatric Service, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
An extreme incongruence between sex and gender identity leads individuals with gender dysphoria (GD) to seek cross-sex hormone therapy (CSHT), and gender-affirming surgery (GAS). Although few studies have investigated the effects of CSHT on the brain prior to GAS, no studies in the extant literature have evaluated its impact during hypogonadism in post-GAS individuals. Here, we aimed to evaluate the effects of estradiol on resting-state functional connectivity (rs-FC) of the sensorimotor cortex (SMC) and basal ganglia following surgical hypogonadism.
View Article and Find Full Text PDFAlcohol Clin Exp Res
September 2019
Peter Boris Centre for Addictions Research, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
Background: Previous neuroimaging studies examining relations between alcohol misuse and cortical thickness have revealed that increased drinking quantity and alcohol-related problems are associated with thinner cortex. Although conflicting regional effects are often observed, associations are generally localized to frontal regions (e.g.
View Article and Find Full Text PDFAddict Behav
November 2019
Homewood Research Institute, Guelph, ON, Canada; Centre for Addiction and Mental Health, Toronto, ON, Canada.
Background: Continuing care is increasingly prioritized in the treatment of substance use disorders (SUDs). Ongoing engagement in continuing care, including mutual support (e.g.
View Article and Find Full Text PDFNat Rev Dis Primers
July 2019
Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Gambling disorder is characterized by a persistent, recurrent pattern of gambling that is associated with substantial distress or impairment. The prevalence of gambling disorder has been estimated at 0.5% of the adult population in the United States, with comparable or slightly higher estimates in other countries.
View Article and Find Full Text PDFAddict Behav
November 2019
Center for Alcohol & Addiction Studies, Brown University, United States.
Introduction: The Alcohol Purchase Task (APT), a behavioral economic measure of alcohol's reinforcing value (demand), has been used to predict the effects of Brief Motivational Intervention (BMI) on alcohol use outcomes. However, it is not known whether BMI may be more or less efficacious, relative to control, among those with different levels of alcohol demand prior to treatment.
Methods: Non college-attending young adults (N = 150) reporting past-month heavy drinking were randomized to a single in-person session of BMI or a relaxation training control (REL).
Addiction
November 2019
Peter Boris Centre for Addictions Research, McMaster University and St. Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
Background And Aims: A cigarette purchase task (CPT) aims to characterize individual variation in the reinforcing value of tobacco. This meta-analysis estimated the associations between cigarette demand, tobacco consumption and nicotine dependence using this task.
Design: A meta-analysis of cross-sectional studies identified by PubMed and PsycINFO databases was conducted.