1 results match your criteria: "Peru (J.A.B.); and Stephenson Cancer Center[Affiliation]"

Immunogenic Treatment of Metastatic Breast Cancer Using Targeted Carbon Nanotube Mediated Photothermal Therapy in Combination with Anti-Programmed Cell Death Protein-1.

J Pharmacol Exp Ther

June 2024

School of Sustainable Chemical, Biological, and Materials Engineering (G.N.F.F., R.P.S., D.R., R.G.H.), School of Biomedical Engineering (C.G.K., S.C., A.W., A.A.), and Samuel Roberts Noble Microscopy Laboratory and School of Biological Sciences (T.G.), University of Oklahoma, Norman, Oklahoma; CHASM Advanced Materials, Inc, Norman, Oklahoma (S.L., R.P.S.); Department of Microbiology and Immunology, Universidad Nacional de San Agustin, Arequipa, Peru (J.A.B.); and Stephenson Cancer Center, Oklahoma City, Oklahoma (R.G.H.)

The high prevalence of breast cancer is a global health concern, compounded by the lack of safe or effective treatments for its advanced stages. These facts urge the development of novel treatment strategies. Annexin A5 (ANXA5) is a natural human protein that binds with high specificity to phosphatidylserine, a phospholipid tightly maintained in the inner leaflet of the cell membrane on most healthy cells but externalized in tumor cells and the tumor vasculature.

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