340 results match your criteria: "Perirectal Abscess"
J Med Case Rep
August 2016
Department of Rheumatology, Johns Hopkins University School of Medicine, 5501 Hopkins Bayview Circle, JHAAC Room 1B.13, Baltimore, MD, 21224, USA.
Background: We report a case in which the extraintestinal manifestations of inflammatory bowel disease preceded development of gastrointestinal symptoms by nearly 9 months in the context of an unusual autoantibody panel, mimicking granulomatosis with polyangiitis. This case highlights the intricacies and overlap of autoimmune diseases, and illustrates an interesting clinical phenotype: cytoplasmic anti-neutrophil cytoplasmic antibody positive inflammatory bowel disease with predominantly extraintestinal manifestations. Perinuclear anti-neutrophil cytoplasmic antibody positivity has been frequently reported in association with inflammatory bowel disease, but cytoplasmic anti-neutrophil cytoplasmic antibody positivity is uncommon.
View Article and Find Full Text PDFTher Apher Dial
April 2016
Division of Nephrology and Hypertension, Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea.
J Pak Med Assoc
January 2016
Department of Immunology, Armed Forces Institute of Pathology, Rawalpindi.
Chronic granulomatous disease is a rare inherited disorder characterised by inability of phagocytes to generate reactive oxygen species needed for intracellular killing of phagocytosed microorganisms. We report the case of an 8-month-old male child with recurrent chest infections and perianal abscess that had no response to conventional antibiotic treatment. His two elder brothers died due to similar complaints at the ages of 4 and 5 months.
View Article and Find Full Text PDFTurk J Pediatr
August 2016
Division of Pediatric Gastroenterology, Department of Pediatrics, Ankara University Faculty of Medicine, Ankara, Turkey.
Chronic granulomatous disease (CGD) is an autosomal recessive or X-linked disorder caused by NADPH oxidase deficiency leading to an impaired ability of reactive superoxide anion and metabolite formation and recurring severe bacterial and fungal infections, with a high mortality rate. Diarrhea, colitis, ileus, perirectal abscess formation and anal fissures are reported gastrointestinal findings in these patients. We report a case of intractable colitis associated with CGD in a young girl.
View Article and Find Full Text PDFWounds
June 2015
Medical College of Wisconsin, Milwaukee, WI.
Pyoderma fistulans sinifica, also known as fox den disease, is a rare and poorly understood inflammatory disorder of the skin and subcutaneous tissues. This disorder is often mistaken for other inflammatory skin disorders and treated inappropriately. The authors describe the case of a 53-year-old male who presented to the colorectal surgery service with a longstanding diagnosis of perirectal Crohn's disease.
View Article and Find Full Text PDFIntest Res
January 2015
Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
Klebsiella pneumoniae (K. pneumoniae) can at times cause invasive infections, especially in patients with diabetes mellitus and a history of alcohol abuse. A 61-year-old man with diabetes mellitus and a history of alcohol abuse presented with abdominal and anal pain for two weeks.
View Article and Find Full Text PDFCan Urol Assoc J
November 2014
Lourdes Hospital, Kochi, India.
Prostatic abscess rarely follows acute prostatitis and can sometimes lead to a fistula by breaking into the prostatic urethra, peri-rectal tissues, the perineum, or the rectum. We report a case of a prostatic abscess tracking into the bulbar urethra after a transurethral resection of the prostate. This created a fistula, mimicking a urethral duplication and leading to urinary incontinence.
View Article and Find Full Text PDFJ Trauma Acute Care Surg
January 2015
From the Johns Hopkins University School of Medicine (B.C.P.), Baltimore, Maryland; and Department of Surgery, University of California, Davis Medical Center (J.M.G., D.H. W.), Sacramento, Maryland.
Background: Trauma and emergency surgery continues to evolve as a surgical niche. The simple fact that The Journal of Trauma is now entitled The Journal of Trauma and Acute Care Surgery captures this reality. We sought to characterize the niche that trauma and emergency surgeons have occupied during the maturation of the acute care surgery model.
View Article and Find Full Text PDFJ Trauma Acute Care Surg
November 2014
From the Departments of Surgery-Trauma/Critical Care (M.L.C.) and Preventive Medicine (M.L.C.), Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Surgery (S.A.), University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin; Department of Surgery (P.M.), University of Cincinnati, Cincinnati, Ohio; Department of Surgery (S.R.), Cooper Medical School of Rowan University, Camden, New Jersey; Department of Surgery (S.Sa.), University of Tennessee Health Science Center, Memphis, Tennessee; Department of Surgery (K.S.), Yale School of Medicine, New Haven, Connecticut; Department of Surgery (GTT), Scripps Memorial Hospital La Jolla, La Jolla, California; Baylor Institute for Health Care Research and Improvement (S.Sh.), Dallas, Texas.
Background: Emergent general surgical diseases encompass a broad spectrum of anatomy and pathophysiology, creating challenges for outcomes assessment, research, and surgical training. The goal of this study was to measure anatomic disease severity for eight emergent general surgical diseases using the uniform grading system of the American Association for the Surgery of Trauma (AAST).
Methods: The Committee on Patient Assessment and Outcomes of AAST applied the previously developed uniform grading system to eight emergent general surgical diseases using a consensus of experts.
BMC Infect Dis
August 2014
Intensive Care Unit, CHU Dupuytren, Limoges, France.
Background: Prostatic abscesses are an uncommon disease usually caused by enterobacteria. They mostly occur in immunodeficient patients. It is thus extremely rare to have a Staphylococcal prostatic abscess in a young immunocompetent patient.
View Article and Find Full Text PDFSurg Endosc
May 2015
Department of General Surgery, Surgical Specialties and Organ Transplantation "Paride Stefanini", Sapienza University, Rome, Italy,
Background: ELRR by TEM is a valid alternative to TME in selected patients with early low rectal cancer, with similar long-term oncological results and better Quality of Life. The authors' policy is to close the residual defect, with possibly a higher risk of dehiscence from tension on the suture line. Aim is to evaluate if a modified technique may reduce the risk of dehiscence.
View Article and Find Full Text PDFIndian J Gastroenterol
September 2014
Institute of Digestive and Hepatobiliary Sciences, Medanta, The Medicity, Sector 38, Gurgaon, Haryana, 122 001, India,
Background: Endoscopic ultrasound (EUS)-guided drainage is an effective treatment for many abscesses in the abdomen. We review our experience with EUS-guided drainage of pelvic abscesses.
Methods: Thirty consecutive patients who underwent EUS-guided pelvic abscess drainage were evaluated after excluding three patients with distance to transducer >2 cm or organized abscess.
J Dermatol
June 2014
Department of Dermatology, Faculty of Medicine, University of Yamanashi, Chuo, Yamanashi, Japan.
Fournier's gangrene (FG) is an infrequent but highly lethal infection. Here we report a 74-year-old man who presented with genital swelling and severe malaise. Based on the physical and imaging examination results, the diagnosis of FG was confirmed.
View Article and Find Full Text PDFCase Rep Emerg Med
May 2014
Center for Policy and Emergency Medicine Research, Oregon Health and Science University, 3181 SW Sam Jackson Boulevard, Portland, OR 97239, USA.
A 12-year-old boy was brought to an urgent care center for fever, back pain, and abnormal gait. In addition to back pain, the patient was found to be persistently febrile but also had decreased perianal sensation and bowel incontinence. He was therefore referred to the emergency department where his back pain improved without medication but he was still febrile with bowel incontinence and persistently decreased perianal sensation.
View Article and Find Full Text PDFMed Clin North Am
May 2014
Division of General Internal Medicine, Department of Medicine, Harborview Medical Center, University of Washington, 325 Ninth Avenue, Box 359780, Seattle, WA 98104, USA. Electronic address:
Anal problems are pervasive, embarrassing and vexing to patients. Primary care providers should be well versed in addressing these concerns, which uncommonly require referral for specialty care. Additionally, anal symptoms and findings may herald previously undiagnosed underlying illness.
View Article and Find Full Text PDFAnn Surg Oncol
May 2014
Division of Surgical Oncology, UC Davis Comprehensive Cancer Center, University of California Davis Medical Center, Sacramento, CA, USA,
Background: Despite effective local therapy with surgery and radiotherapy (RT), ~50 % of patients with high-grade soft tissue sarcoma (STS) will relapse and die of disease. Since experimental data suggest a significant synergistic effect when antiangiogenic targeted therapies such as sorafenib are combined with RT, we chose to evaluate preoperative combined modality sorafenib and conformal RT in a phase I/II trial among patients with extremity STS amenable to treatment with curative intent.
Methods: For the phase I trial, eight patients with intermediate- or high-grade STS >5 cm in maximal dimension or low-grade STS >8 cm in maximal dimension received concomitant sorafenib (dose escalation cohort 1:200 twice daily, cohort 2:200/400 daily) and preoperative RT (50 Gy in 25 fractions).
Neurol Sci
April 2014
Operative Unit of Neurophysiopathology, CTO, Rome, Italy.
Genomics
July 2014
Center for Pediatric Genomic Medicine, Children's Mercy Hospital, Kansas City, MO 64108, USA; Department of Pediatrics, Children's Mercy Hospital, Kansas City, MO 64108, USA; Department of Pathology, Children's Mercy Hospital, Kansas City, MO 64108, USA; School of Medicine, University of Missouri-Kansas City, Kansas City, MO 64110, USA. Electronic address:
Pediatric-onset inflammatory bowel disease (IBD) is known to be associated with severe disease, poor response to therapy, and increased morbidity and mortality. We conducted exome sequencing of two brothers from a non-consanguineous relationship who presented before the age of one with severe infantile-onset IBD, failure to thrive, skin rash, and perirectal abscesses refractory to medical management. We examined the variants discovered in all known IBD-associated and primary immunodeficiency genes in both siblings.
View Article and Find Full Text PDFTech Coloproctol
February 2014
Department of Radiology, Innsbruck Medical University, Anichstrasse 35, 6020, Innsbruck, Austria,
Background: Successful anal fistula care in complex cases can be assisted by specialized imaging which accurately defines the site of the internal fistula opening and the fistula type. There are currently limited data concerning the clinical indications for and accuracy of transperineal ultrasound (TP-US) in acute perianal sepsis. The aims of this study were to compare the anatomical interpretation of TP-US images with magnetic resonance imaging (MRI) and surgical findings in an unselected patient cohort presenting with acute perianal sepsis.
View Article and Find Full Text PDFColorectal Dis
August 2013
Department of Surgery and Transplantation, Tel Hashomer Hospital, Ramat Aviv, Israel.
Aim: Successful anal fistula care is aided by specialized imaging accurately defining the site of the internal opening and fistula type. Imaging techniques are complementary, designed to answer specific anatomical questions. There are limited data concerning the clinical value of transperineal ultrasound (TP-US) in both cryptogenic fistula-in-ano and perianal Crohn's disease (PACD).
View Article and Find Full Text PDFJ Pediatr Surg
February 2013
Department of General Surgery, Mayo Clinic, Phoenix, AZ, USA.
Tailgut cysts are uncommon lesions that usually occur within the presacral space. The relative rarity and nonspecific complaints associated with these lesions often lead to misdiagnosis or unnecessary procedures before the correct diagnosis is made. We describe a case of a 16-year-old female who presented with pelvic pain.
View Article and Find Full Text PDFJ Surg Case Rep
June 2013
Department of Surgery, Berkshire Medical Center/University of Massachusetts Medical School, Pittsfield, MA, USA.
Supralevator abscesses are the rarest manifestation of anorectal suppurative disease. We report a supralevator abscess in a 60-year-old male whose earliest presentation included poorly localized abdominal and pelvic pain, tenesmus, urinary retention and weight loss, initially treated as diverticular disease based upon imaging and presentation. Progressive symptoms led to the discovery of a pelvic abscess with subsequent percutaneous drainage, later followed by emergent laparotomy, where a single perforated diverticulum was revealed to be the source fistulization.
View Article and Find Full Text PDFJ Huazhong Univ Sci Technolog Med Sci
October 2012
Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Fournier's gangrene (FG) is an extremely aggressive and rapidly progressive polymicrobial soft tissue infection of the perineum, anal area or genitalial regions with a high mortality rate. The objectives of this study were to share our experience with the management of this serious infectious disease over the last 15 years. This retrospective study examined 24 patients diagnosed as having FG who were admitted to our hospital between March 1996 and December 2011.
View Article and Find Full Text PDFCase Rep Infect Dis
October 2012
School of Medicine, University of Pittsburgh, S532 Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15213, USA.
Perirectal abscess is a common colorectal condition that may be present with or without a fistula. In most cases where a fistula coexists the organisms cultured are gut-derived organisms whereas skin-derived organisms are more common in patients without fistula formation. Candida albicans, despite being an microorganism often found in the gastrointestinal tract, has not previously been reported as an isolate from a perirectal abscess culture.
View Article and Find Full Text PDFSurg Infect (Larchmt)
October 2012
Department of General Surgery, North Middlesex University Hospital National Health Service Trust, Sterling Way, London, United Kingdom.
Background: Perirectal abscess is encountered commonly in surgical practice, and simple incision and drainage usually is sufficient. However, life-threatening sepsis may occur. In such instances, the high morbidity and mortality rates from the severe systemic inflammatory response syndrome (SIRS) associated with rapidly evolving necrotizing and gas-forming soft tissue infections are of major concern.
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