2,345 results match your criteria: "Perioperative Management of the Diabetic Patient"

Background: The American Association of Hip and Knee Surgeons (AAHKS) strongly recommends the use of dexamethasone in patients undergoing total joint arthroplasty (TJA) due to its therapeutic effects. However, use in diabetic patients is controversial due to safety. Therefore, the objective of this study was to determine safety: (1) calculating the post-operative glucose levels; (2) finding the ideal dexamethasone dosing regimen; and (3) reporting complications of dexamethasone administration in diabetic patients undergoing TJA.

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Association and predictive ability between significant perioperative cardiovascular adverse events and stress glucose rise in patients undergoing non-cardiac surgery.

Cardiovasc Diabetol

December 2024

Department of Anesthesiology, Shengli Clinical Medical College of Fujian Medical University, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134, Dongjie, Fuzhou, 350001, China.

Background: The predictive importance of the stress hyperglycemia ratio (SHR), which is composed of admission blood glucose (ABG) and glycated hemoglobin (HbA1c), has not been fully established in noncardiac surgery. This study aims to evaluate the association and predictive capability the SHR for major perioperative adverse cardiovascular events (MACEs) in noncardiac surgery patients.

Methods: Individuals who underwent noncardiac surgical procedures between 2011 and 2020, including both diabetic and non-diabetic patients, were identified in the perioperative medicine database (INSPIRE 1.

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: Artri King is an over-the-counter supplement previously marketed to treat joint pain and arthritis. In 2022, the Food and Drug Administration (FDA) issued a product warning after it discovered Artri King contained hidden ingredients including dexamethasone, diclofenac, and methocarbamol. Given the risk of adrenal insufficiency in the context of long-term dexamethasone use, we sought to report on adverse endocrinologic outcomes observed among patients endorsing the use of these supplements who presented to an orthopedic surgery clinic at a county safety net hospital.

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Background And Objective: The global prevalence of diabetes mellitus has markedly risen in recent years. Consequently, there has been a rise in the number of patients with diabetes undergoing cardiac surgery. Despite the existence of national and international guidelines to improve surgical outcomes in patients with diabetes, perioperative diabetes management optimisation remains inadequate resulting in these patients experiencing increased rates of surgical morbidity and mortality.

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Analysis of The 2024 ESC/EACTS Guidelines For The Management Of Atrial Fibrillation.

J Cardiothorac Vasc Anesth

November 2024

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN. Electronic address:

The 2024 European Society of Cardiology guidelines for atrial fibrillation (AF) emphasize a patient-centered approach to management, structured around the AF-CARE pathway: Comorbidity and risk factor management (C), Avoiding stroke and thromboembolism (A), Reducing symptoms through rate and rhythm control (R), and Evaluation and dynamic reassessment (E). This framework ensures that comorbidities such as hypertension, heart failure, diabetes, and obesity are effectively managed to prevent disease progression and improve outcomes. A key principle of the guidelines is shared decision making involving patients, families, caregivers, and healthcare teams to ensure individualized care that reflects patient preferences.

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Craniopharyngiomas are rare tumors arising in the suprasellar area of the brain and are more common in the pediatric age group. Due to the involvement of the hypothalamus, central diabetes insipidus (DI) is usually associated with such lesions. Patients with DI are at risk for significant electrolyte disturbances due to high urine output and the potential for sodium imbalance.

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Perioperative pulmonary aspiration is a critical complication linked to significant morbidity and mortality, particularly in high-risk populations such as patients with diabetes, obesity, gastroparesis, or those using Glucagon-Like-Peptide-1 receptor agonists (GLP-1 RAs). Standard fasting protocols may not be appropriate for these patients, as they have increased propensity of delayed gastric emptying, hence increasing the complex of the preoperative risk assessment. Gastric ultrasound (GUS) provides a non-invasive, reliable method for assessing gastric content and volume, enabling anaesthesia professionals to make informed decisions regarding aspiration risk, airway management, and surgical scheduling.

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Introduction: This study aimed to standardize perioperative interruption of antiplatelet agents in patients undergoing cervical spinal surgery and investigate the incidence of epidural hematoma and thrombotic complications.

Methods: A total of 153 patients, consisting of 85 men and 68 women, were included in this study. Their mean age was 65.

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Aims: Our study examined the association between the Cambridge Risk Score (CRS), new hyperglycemia (NH), and complications in patients undergoing elective surgery.

Methods: In this retrospective cross-sectional study, adult surgical patients, without diabetes, with NH (blood glucose ≥140 mg/dL) were identified, and the CRS was calculated. We used univariate regression models to evaluate the relationship between CRS and NH with 30-day readmission, length of stay (LOS), and complications.

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Article Synopsis
  • Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are commonly used medications for managing diabetes and aiding weight loss but can delay gastric emptying, increasing aspiration risk during surgery.
  • Current guidelines suggest pausing these medications before surgery based on expert consensus rather than clear evidence.
  • A case series demonstrates how gastric point of care ultrasound (POCUS) assessed gastric contents in three patients, allowing for tailored and safer anesthetic plans based on individual needs and urgency.
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Gender differences in the incidence of saphenous vein graft intervention.

J Cardiothorac Surg

December 2024

Department of Cardiology, Barzilai Medical Center, The Ben-Gurion University of the Negev, Hahistadrout 2, 7830604, Ashkelon, Israel.

Article Synopsis
  • The study investigated gender differences in outcomes of saphenous vein graft percutaneous coronary intervention (SVG PCI) after coronary artery bypass grafting (CABG) among patients treated for acute coronary syndrome (ACS).
  • Researchers analyzed data from 72 patients at Barzilai Medical Center between 2010 and 2023, finding that men had higher SVG PCI rates, while women experienced earlier graft failures.
  • The findings suggest that gender-specific strategies in post-CABG care could enhance patient outcomes and emphasize the importance of tailoring follow-up interventions based on patient gender.
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  • Diabetes mellitus (DM) is a common issue in patients undergoing total knee arthroplasty (TKA), and the study investigates the effects of a medication class called SGLT2 inhibitors (SGLT2i) on postoperative complications for these patients.
  • The research analyzed data from the PearlDiver database, identifying DM patients who underwent TKA and comparing those on SGLT2i with matched control patients on various health factors.
  • Findings show that while SGLT2i use is linked to a higher risk of several early postoperative complications, it also results in a reduced need for blood transfusions, which can inform surgical decisions for diabetic patients.
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Article Synopsis
  • * A modified Delphi methodology will be employed to gather opinions from a diverse group of UK experts through a series of anonymous surveys, aiming for consensus on effective pain management techniques.
  • * The study seeks to analyze expert agreement using structured feedback and will only continue if a consensus of at least 75% is reached among participants, although ethical approval was deemed unnecessary.
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Article Synopsis
  • Lower-extremity amputations are commonly caused by complications from diabetes mellitus and peripheral vascular disease, with traditional socket prostheses being the standard, while transcutaneous osseointegration for amputees (TOFA) is emerging as a potential alternative, particularly needing research for diabetic patients.* -
  • A study reviewed 17 patients with well-controlled diabetes who underwent unilateral transfemoral TOFA, tracking perioperative complications, additional surgeries, mobility, and quality of life over two years, finding no major systemic complications or deaths.* -
  • Results indicated that some patients experienced minor complications, but the majority showed significant improvements, such as an increase in daily prosthesis wear time from 36% to 79% of patients wearing it
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Article Synopsis
  • Germs can infect surgical wounds if a patient's immunity is low, indicated by pus, which may require further operations to drain the wound effectively.
  • A study conducted on 180 orthopedic patients with closed long bone fractures examined the rate and causes of post-surgical infections, monitoring them for symptoms and collecting bacterial cultures over six months.
  • The findings revealed a 7.22% infection rate, with Staphylococcus aureus being the most common bacterium; some infections were treated with irrigation or antibiotics, highlighting the ongoing challenge of managing post-operative infections.
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  • The study investigates the impact of controlled versus uncontrolled hypertension on the outcomes of patients undergoing elective Endovascular Aneurysm Repair, using a national database to enhance preoperative care.
  • Patients were categorized based on their hypertension status and tracked for outcomes like perioperative death and other complications, from a larger group including both hypertensive and non-hypertensive individuals.
  • The results showed that patients with uncontrolled hypertension had significantly worse outcomes compared to those with controlled hypertension and non-hypertension, indicating the need for better preoperative management in hypertensive patients.
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  • The study aimed to understand how diabetes mellitus (DM) affects recovery and survival in patients with gastric cancer who underwent radical gastrectomy, using a method called propensity score matching to compare outcomes.
  • It involved analyzing 2,508 patients, finding that 11.8% had DM, and after matching, complications in DM patients were notably higher, leading to longer hospital stays, but overall survival rates were similar between DM and non-DM patients.
  • Factors like older age, lower BMI, larger tumor sizes, and severe complications were identified as independent risks influencing overall survival in these patients.
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Long-Term Prognosis of Coronary Aneurysms: Insights of CAAR, an International Registry.

JACC Cardiovasc Interv

November 2024

Interventional Cardiology, Hospital Clínico San Carlos, IdISSC, Madrid, Spain; Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain; Cardiology, Hospital Universitario de Torrejón, Madrid, Spain; Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain. Electronic address:

Article Synopsis
  • Researchers studied 1,729 patients with coronary artery aneurysms (CAAs) to understand their clinical characteristics and predict outcomes, using data from an international registry across 9 countries.
  • The majority of patients were male (78.6%) averaging 66 years old, with significant cardiovascular issues such as coronary artery disease (85.8%) and a median of 1 aneurysm per patient, primarily affecting the left anterior descending artery.
  • During a median follow-up of about 45 months, 21.9% of patients died, and 37.1% experienced major adverse cardiovascular events; factors like age, diabetes, and kidney disease were linked to worse outcomes.
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The Predictive Role of Inflammatory Biomarkers and Their Correlation with the Biochemical Profile in Patients with Vasculopathy Undergoing Surgery.

Int J Mol Sci

November 2024

Department of Chemistry and Medical Biochemistry, Faculty of Medicine in English, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu Mureş, 540139 Targu Mures, Romania.

Article Synopsis
  • * The study evaluated 62 patients (both diabetic and non-diabetic) undergoing lower limb surgeries, measuring various inflammatory and biochemical markers before and after the procedures.
  • * Key findings showed correlations between specific markers (like IL-6 and TNF-α) and complications, indicating that monitoring these factors can help identify patients at higher risk and improve their management.
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Article Synopsis
  • Diabetes mellitus (DM) is a condition marked by high blood sugar levels due to inadequate insulin production, requiring patients to undergo long-term treatment with existing hypoglycemic drugs, which are often ineffective for managing the disease.
  • Traditional weight loss surgeries, like gastric bypass, have strict BMI requirements and can lead to complications such as hypoglycemia and dumping syndrome, reducing their effectiveness for DM treatment.
  • Jejunoileostomy is a newer surgical option showing promise for improving glucose and lipid metabolism without altering the gastrointestinal structure, resulting in fewer complications and better management of DM-related issues, supported by clinical consensus on its surgical and postoperative management.
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  • Metabolic and bariatric surgery (MBS) can lead to postoperative complications, particularly acute kidney injury (AKI), with historical rates ranging from 5.8% to 8.6% but more recent findings show a lower incidence of 3% among participants.
  • The study aimed to identify the risk factors contributing to AKI after MBS, which included male gender, hypertension, and extended surgical duration, using data from adult patients treated between 2008 and 2022.
  • Notably, among those who experienced AKI, 13.7% required dialysis, and 5.9% progressed to chronic renal failure necessitating a transplant, highlighting the critical nature of monitoring kidney health post-surgery.
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Article Synopsis
  • * Bariatric and metabolic surgery (BMS) has transformed T2DM treatment for obese patients, leading to the idea of onco-metabolic surgery (OMS), which integrates tumor removal and T2DM management in a single operation.
  • * There are key differences between OMS and BMS, emphasizing the need for tailored approaches in applying OMS for gastric cancer patients to improve their clinical outcomes.*
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  • This study compares tissue damage and hidden blood loss (HBL) in two minimally invasive spinal procedures: unilateral biportal endoscopic lumbar discectomy (UBE) and percutaneous endoscopic interlaminar discectomy (PEID), focusing on identifying risk factors for HBL.
  • Conducted with 159 patients, results showed that the average HBL was significantly higher in the UBE group (431 ml) compared to the PEID group (328 ml), highlighting a notable difference in the two techniques.
  • Correlational analyses found that operation time was a consistent independent risk factor for HBL in both groups, with additional factors varying between the procedures, such as preoperative hematocrit in UBE and diabetes in PE
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Article Synopsis
  • Duplication of the gallbladder is an uncommon condition that can complicate surgical procedures, potentially leading to increased risks during surgery.
  • A 51-year-old diabetic man with acute cholecystitis was accurately diagnosed with a rare double gallbladder, leading to an effective laparoscopic cholecystectomy after initial conservative treatment failed.
  • This case underscores the importance of tailored surgical approaches and highlights knowledge on managing rare biliary conditions in the medical field.
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Article Synopsis
  • * A case study details a 60-year-old man with type 2 diabetes and metastatic melanoma who developed euglycemic diabetic ketoacidosis (DKA) during and after brain surgery, despite having normal blood sugar levels.
  • * Effective management of euglycemic DKA involves recognizing its subtle symptoms, administering intravenous insulin with dextrose, correcting metabolic issues, and stopping SGLT2i use, especially in surgical settings.
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