1,778 results match your criteria: "Perianal Abscess"

Article Synopsis
  • The study investigated whether antibiotics influence the development of anal fistulas after surgery for perianal abscesses, hypothesizing that they do not have an effect.
  • Conducted as a single-blinded randomized trial, patients were divided into two groups: one received antibiotics post-surgery and the other did not, with outcomes measured over one year.
  • Results showed no significant difference in the formation of anal fistulas (16.3% vs 10.2%) or recurrent abscesses (9.2%) between the two groups, concluding that antibiotics do not impact these complications.
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Salvage surgery for pouch-related complication after ileal pouch-anal anastomosis: a report of two cases.

Surg Case Rep

May 2024

Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka E-2, Suita, Osaka, 565-0871, Japan.

Background: Pouch-related complications (PRCs), such as pelvic abscesses and perianal complex fistulas, can occur after ileal pouch-anal anastomosis (IPAA) in ulcerative colitis (UC). They are often difficult to treat and require salvage surgery. We report two cases of PRC associated with fistulas.

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Suspected coexistence of perianal necrotizing sweet syndrome in chronic myelomonocytic leukemia: A case report.

World J Gastrointest Surg

April 2024

Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

Background: Chronic myelomonocytic leukemia (CMML) complicated with Sweet syndrome (SS) is a rare hematological neoplasm. However, cases of concomitant development of perianal necrotizing SS (NSS) have not been reported.

Case Summary: We report a case of a 49-year-old male patient who underwent sequential procedures for hemorrhoids and perianal abscess.

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Background And Objectives: Extra-intestinal salmonellosis is associated with higher case fatality and is underestimated in the developing countries like India. Here we present a case series of bacteriologically proven extra-intestinal salmonellosis managed at our institute over the past two years.

Materials And Methods: Retrospective analysis of bacteriologically proven extra-intestinal salmonellosis over two years between January 2020 to December 2021 was carried out.

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Anal Cryptoglandular Suppuration: Evidence-Based Management.

Surg Clin North Am

June 2024

Department of Surgery, Madigan Army Medical Center General Surgery Residency, Joint Base Lewis-McChord, WA 98431, USA. Electronic address:

Anal suppurative processes are commonly encountered in surgical practice. While the initial therapeutic intervention is philosophically straightforward (incision and drainage), drainage of the appropriate space and treatment of the subsequent fistula in ano require a thorough understanding of perianal anatomy and nuanced decision making. Balancing the risk of fecal incontinence with simple fistulotomy versus the higher risk of fistula recurrence with all sphincter-sparing fistula treatments can be a challenge for surgeons and patients alike.

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Complex perianal fistula is a common complication of Crohn's disease (CD) which leads to negative impact on patient's quality of life. Successful management of the disease requires a multidisciplinary approach, including a gastroenterologist and a colorectal surgeon, applying combined surgical and medical therapy. One of frequently practiced surgical procedures is seton placement in the fistula tract, which is used to control perianal sepsis and drain the fistula, while preventing recurrent abscess formation.

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Article Synopsis
  • - The study focused on 16 Iranian patients with very early-onset inflammatory bowel disease (VEO-IBD), aiming to explore the role of underlying genetic issues related to inborn errors of immunity (IEI) in this condition.
  • - Most patients were young (median age of 43.5 months), with symptoms starting around 4 months; common signs included chronic diarrhea and perianal diseases, with a notable prevalence of consanguinity among parents.
  • - Whole exome sequencing (WES) revealed genetic variants in 81.3% of patients, highlighting notable gene mutations like IL10RB, and emphasizing the need for genetic evaluation in early-onset IBD cases due to the high incidence of mon
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Objective:  There is limited data on the pathogenic microorganisms associated with anorectal abscesses. The purpose of this study was to retrospectively analyze the types and quantities of pathogenic microorganisms in the pus cultures of patients with anorectal abscesses and to explore the correlation between pathogenic microorganisms and types of anorectal abscesses.

Methods:  A retrospective analysis was conducted on the microbiological data of 517 inpatient surgical patients with anorectal abscesses treated at a single center from January 2017 to December 2021.

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Article Synopsis
  • Anorectal infections can be serious complications for patients with neutropenic leukemia, caused by a combination of mucosal damage, low white blood cell counts, and weakened immune responses.
  • Early diagnosis is crucial and relies on recognizing symptoms and using imaging techniques to identify signs of inflammation or fluid buildup.
  • The review aims to clarify the underlying mechanisms and symptoms of these infections, suggest ways to diagnose them, and address the lack of consensus on treatment methods.
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Complications can arise secondary to anorectal suppurative diseases, with infections spreading along the extraperitoneal space, such as the peri-vesical, prevesical, pre-sacral, and pararectal spaces, resulting in abscesses at remote sites, which can make diagnosis more challenging. Due to the absence of peritonitis symptoms, there is a delay in presentation among such patients. Comprehending the intricacies of these areas and the way infection can spread within them is crucial for promptly identifying and effectively draining the extraperitoneal abscess.

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Crohn's disease (CD) is an inflammatory condition affecting the gastrointestinal tract, often leading to persistent inflammation in various parts, notably the terminal ileum and colon. Clinical manifestations of CD can become complex due to complications like strictures, fistulas, and perianal abscesses. The disease typically exhibits transmural inflammation and skip lesions, where unaffected areas alternate with affected ones.

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Article Synopsis
  • Infantile inflammatory bowel disease (IBD) primarily affects children under two years, often involving genetic factors and tends to be more severe and resistant to standard treatments compared to older children with IBD.
  • A 16-month-old boy with consanguineous parents experienced severe IBD symptoms, including perianal fistulas and growth issues, leading to surgery and a diagnosis of Crohn's disease.
  • Genetic testing identified mutations in receptor-interacting protein kinase 1, and despite starting a treatment regimen involving adalimumab, he developed further complications requiring additional surgical intervention.
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Article Synopsis
  • - Endoanal ultrasound (EAUS) is an important imaging tool for assessing anal and perianal conditions and is beneficial for both benign issues and staging anal/rectal tumors.
  • - EAUS offers advantages over MRI, such as lower cost, better patient comfort, and wider applicability for those who can't undergo MRI, yet it remains underutilized worldwide.
  • - The article aims to educate medical professionals on EAUS procedures, covering indications, patient preparation, imaging techniques, challenges, and a comparison with other imaging methods.
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Long-term outcome of stem cell transplantation with and without anti-tumor necrotic factor therapy in perianal fistula with Crohn's disease.

World J Stem Cells

March 2024

Division of Colon and Rectal Surgery, Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, South Korea.

Background: Stem cell transplantation is a promising therapeutic option for curing perianal fistula in Crohn's disease (CD). Anti-tumor necrotic factor (TNF) therapy combined with drainage procedure is effective as well. However, previous studies are limited to proving whether the combination treatment of biologics and stem cell transplantation improves the effect of fistula closure.

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Background/aims: A poor prognostic factor for Crohn's disease (CD) includes perianal fistulizing disease, including perianal fistula and/or perianal abscess. Currently, a tool to assess perianal symptoms in patients with CD remains nonexistent. This study aimed to develop a perianal fistulizing disease self-screening questionnaire for patients with CD.

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Background: Perianal abscesses are common presentations and reasons for emergency general surgery admissions. Management involves incision and drainage of the abscess and packing the cavity with internal wound dressings. This meta-analysis aimed to assess in adults if packing an abscess or leaving it unpacked leads to a significant difference in the outcomes of pain on wound dressing, time to healing, rate of fistulation and abscess recurrence.

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Infections with non-typhoidal salmonella (NTS) most commonly cause localised infections such as cutaneous abscesses in humans and are a leading source of foodborne illness. Here, we present a unique case of NTS Choleraesuis in a perianal abscess in an immunocompetent patient without any comorbidities.A woman in her late 40s was diagnosed with a perianal abscess with an unknown origin of infection.

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BACKGROUND The incidence of human immunodeficiency virus (HIV) infection is on the rise, and perianal region diseases in HIV-infected patients have become increasingly prevalent. This study aimed to analyze the surgical treatment outcomes of HIV-infected patients presenting with perianal concerns. MATERIAL AND METHODS We included 311 HIV-positive patients admitted to the Infectious Diseases Clinic of Samsun Training and Research Hospital between January 2014 and December 2022.

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Background: Perianal injuries in adults with hematologic malignancies can result in sepsis or death. Patients on a 36-bed acute care oncology unit experienced increased perianal injuries from 2018 to 2021 based on a chart review, which revealed that 24 patients with leukemia, all of whom had received cytarabine, developed perianal injuries.

Objectives: This study examined whether a nurse-led educational intervention would decrease perianal injuries.

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A 44-year-old man with hypertension and dyslipidemia presented with pain in the buttocks. The patient was diagnosed with perianal ischiorectal fossa abscesses and cellulitis. He was subsequently diagnosed with a perineal subcutaneous abscess after a week, a right lower leg impetigo after a month, right periorchitis, a scrotal abscess, and Fournier's gangrene after two months.

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Fournier's gangrene due to rectal cancer: A case report.

Mol Clin Oncol

April 2024

Department of Gastrointestinal Surgery, Peking University People's Hospital, Beijing 100044, P.R. China.

Article Synopsis
  • Fournier's gangrene (FG) is a rare and dangerous infection often caused by necrotizing fasciitis, and this study highlights a unique case linked to rectal cancer perforation in a 57-year-old man.
  • The patient was initially misdiagnosed, but after surgery to remove infected tissue and with the help of broad-spectrum antibiotics and a colostomy, he recovered well.
  • The case emphasizes the importance of quick intervention and teamwork among medical professionals in managing severe FG, providing insight into effective treatment strategies for similar patients in the future.
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Article Synopsis
  • The study focused on pediatric patients with anal fistula treated using video-assisted anal fistula treatment (VAAFT) and assessed the effectiveness of ozonide oil for postoperative wound dressing.
  • A total of 33 VAAFT procedures were conducted on 30 children, with a median age of 5.7 years, and the majority of cases were idiopathic in nature.
  • Results indicated that VAAFT is a safe and effective treatment, with a median healing time of 28 days and low recurrence rates, although further studies are needed for more comprehensive conclusions.
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Background: Perianal fistula is clinically diagnosed and commonly characterized using magnetic resonance imaging (MRI). Diffusion-weighted imaging (DWI) and T2-weighted imaging are emerging techniques that can obviate the need for contrast injection in cases where contrast administration is not feasible or contraindicated. The main objective of our study was to compare the efficacy of the combination of DWI and T2 STIR (short tau inversion recovery) imaging with contrast-enhanced MRI for the diagnosis and characterization of perianal fistula.

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Background & Aims: We assessed Modified Multiplier Simple Endoscopic Score for Crohn's Disease (MM-SES-CD) and Simple Endoscopic Score for Crohn's Disease (SES-CD) thresholds that are best associated with low likelihood of long-term disease progression.

Methods: Data from 61 patients with early Crohn's disease (CD) who participated in the CALM long-term extension study were used as the derivation cohort and validated using the McMaster inflammatory bowel disease database (n = 99). The primary outcome was disease progression (new internal fistula/abscess, stricture, perianal fistula or abscess, CD-related hospitalization or surgery) since the end of the CALM trial.

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