Unraveling the Molecular Threads: A Comprehensive Review of the Pathogenesis and Therapeutic Insights Into Allergic Rhinitis.

Allergic rhinitis (AR) is a prevalent inflammatory disorder of the nasal mucosa, triggered by allergen exposure and characterized by symptoms such as sneezing, nasal congestion, itching, and rhinorrhea. This comprehensive review aims to unravel the molecular mechanisms underpinning AR, exploring the pathogenesis from allergen recognition to chronic inflammation and tissue remodelling. Central to the disease are immunoglobulin E (IgE)-mediated hypersensitivity reactions, involving key inflammatory mediators and cellular players such as mast cells, eosinophils, and T cells.

Evaluating the Role of Glycemic Control in Modulating Pulmonary Function Among Smokers With Diabetes Mellitus: A Systematic Review.

Background: Diabetes mellitus (DM) impacts multiple body systems, including lung function, and this impact can be further complicated by smoking. The connection between blood sugar control and lung health in individuals with diabetes who smoke has been extensively studied, but findings have been varied. This systematic review sought to compile and assess the research on how blood sugar control influences lung function in smokers with diabetes.

Comparison of the Clinical Efficacy of Herbal, Chlorhexidine, and Normal Saline Mouthwash in the Management of Chronic Gingivitis.

Background: The incidence of chronic gingivitis, a widespread inflammatory condition of the gums, is considerable across the demographic spectrum, with potential progression to advanced periodontal pathology in the absence of intervention. The objective of this investigation was to conduct a comparative analysis of the clinical effectiveness of various oral rinses in mitigating the symptoms of chronic gingivitis.

Methods: This empirical study was conducted within the confines of the Department of Oral Medicine and Radiology.

Radiographical Evaluation of Morphological Alterations of Mandibular Third Molars: A Cone Beam Computed Tomography (CBCT) Study.

Introduction  Morphological changes or variations in the lower third molar can be of concern during the endodontic, orthodontic, or prosthetic intervention. The goal of the present study was to evaluate the morphological alterations in the roots and root canal of a mandibular third molar in Bhopal, Central India, on cone beam computed tomography (CBCT) images. Methodology CBCT scans of 277 mandibular molars, of both genders, between the ages of 18 and 60 years were assessed for the presence of root numbers, the configuration of the canal based on Vertucci's categorization, and a C-shaped canal.

Calcifying epithelial odontogenic tumour of the maxilla - A rare case report.

A calcifying epithelial odontogenic tumour (CEOT) is a rare benign odontogenic tumour, which was first described by J. J. Pindborg in 1955, hence it is also called the Pindborg tumour.

A Comparative Study of Success Rates of Post and Core Treated Anterior and Posterior Teeth Using Cast Metal Posts.

Background: Post and core restorations are performed (generally after treating the root canals of the tooth) when the majority of the tooth structure has been rendered ineffective to support itself/the crown of the tooth. In this clinical study, we aim to compare the difference between post and core treatment of anterior and posterior teeth and their success/failure rates.

Objective: Our investigation aimed to compare the clinical survival rates of custom-fabricated cast metal post-and-cores in cases of anterior and posterior teeth while controlling for the population's age and gender, type of post material, length of the post, amount of alveolar bone tissue supporting the roots, tooth location in the dental arch, and type of cement used, as well as the effect of opposing dentition and the type of definitive prosthetic treatment received.

The Status, Need, and Influence of Dental Prosthetics on Oral Health-Related Quality of Life in the Geriatric Population: An Epidemiological Survey.

Background An epidemiological survey was conducted among the geriatric population to determine the status and need for dental prosthetics and their influence on oral health-related quality of life (OHRQoL). Methodology The study population consisted of 270 patients aged 60 or older. All pertinent demographic information, clinical data on prosthesis status and need, and the Oral Health Impact Profile (OHIP)-14 questions to assess OHRQoL were collected using a pretested structured questionnaire written in the patient's native tongue.

Accuracy of marginal fit of an implant-supported framework fabricated by 3D printing versus subtractive manufacturing technique: A systematic review and meta-analysis.

Statement Of Problem: Evidence comparing additive 3-dimensional printing (3DP) with subtractive milling for implant-supported frameworks is lacking.

Purpose: The purpose of this systematic review and meta-analysis was to compare the marginal fit and accuracy of complete arch implant-supported frameworks (CA), implant-retained fixed partial dentures (IRFPDs), single implant crowns (SICs), and interim implant-retained restorations (IIRRs) by using additive manufacturing (AM) and subtractive manufacturing (SM) methods.

Material And Methods: An electronic search was performed in PubMed, ScienceDirect, Google Scholar, and the Cochrane Library for articles published up to August 2020.

Comparison of efficacy of local anesthetic solution, distilled water and normal saline as emergency fixatives.

Context: Adequate tissue fixation is fundamental to good quality histological sections. Owing to undesirable effects of 10% buffered formalin, its availability in clinics is questionable. Thus, the present study was conducted with a novel approach to fixation, together with the scope of finding fixative properties of more commonly used reagents available at the clinics.

Impact of oral health education by audio aids, braille and tactile models on the oral health status of visually impaired children of Bhopal City.

Context: Children with special needs face unique challenges in day-to-day practice. They are dependent on their close ones for everything. To improve oral hygiene in such visually impaired children, undue training and education are required.

Effect of three different antioxidants on the shear bond strength of composite resin to bleached enamel: An in vitro study.

Objective: The effect of 10% sodium ascorbate, 10% grape seed extract, and 10% pine bark extract on the shear bond strength of composite resin to bleached enamel was evaluated.

Materials And Methods: Ninety recently extracted human premolars were divided into six groups of 15 teeth each. Except Group I (negative control), the labial enamel surface of all specimens in the other groups were bleached with 37.

Effect of remineralizing agents on surface microhardness of primary and permanent teeth after erosion.

Purpose: The purposes of this study were to compare the susceptibility of human primary and permanent enamel to dental erosion caused by soft drinks and to compare in vitro the remineralization potential of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste, 1.23 percent acidulated phosphate fluoride (APF) gel, and iron supplement.

Methods: Fifteen extracted primary and permanent teeth were used for sample preparation.

Stem cells: A potential regenerative future in dentistry.

In recent years, the field of dentistry has embossed its presence by taking major leaps in research and further bringing it into practice. The most valuable ongoing research in regenerative dentistry is the study on stem cells. It was instituted that stem cells grow rapidly and have the potential to form specialized dentin, bone, and neuronal cells.

Evaluation of resorbable membrane in treatment of human gingival isolated buccal recession.

Background: Gingival recession in its localized or generalized form is an undesirable condition which results in root exposure. Several different techniques have been described in order to cover the exposed root surface, and increase the dimensions of the keratinized tissue in gingival recession defects. The aim of the present study is to evaluate the result using a bio resorbable membrane for the treatment of human isolated buccal gingival recession.