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PANoptosis: a new insight for oral diseases.

Mol Biol Rep

September 2024

Department of Orthodontics, Stomatological Hospital of Chongqing Medical University, #426 SongShiBeiRd., YuBei, Chongqing, 401147, People's Republic of China.

PANoptosis, a burgeoning area of research, is a unique type of programmed cell death typified by pyroptosis, apoptosis, and necroptosis, yet it defies singular classification by any one mode of death. The assembly and activation of PANoptosomes are pivotal processes in PANoptosis, with several PANoptosomes already identified. Linkages between PANoptosis and the pathophysiology of various systemic illnesses are established, with increasing recognition of its association with oral ailments.

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