Bone marrow mesenchymal stem cells overexpressing human basic fibroblast growth factor increase vasculogenesis in ischemic rats.

Administration or expression of growth factors, as well as implantation of autologous bone marrow cells, promote in vivo angiogenesis. This study investigated the angiogenic potential of combining both approaches through the allogenic transplantation of bone marrow-derived mesenchymal stem cells (MSCs) expressing human basic fibroblast growth factor (hbFGF). After establishing a hind limb ischemia model in Sprague Dawley rats, the animals were randomly divided into four treatment groups: MSCs expressing green fluorescent protein (GFP-MSC), MSCs expressing hbFGF (hbFGF-MSC), MSC controls, and phosphate-buffered saline (PBS) controls.

Thyroid antibodies and risk of preterm delivery: a meta-analysis of prospective cohort studies.

Background: Observational studies suggest possible associations between thyroid antibodies and risk of preterm delivery. However, whether thyroid antibodies are risk factors of preterm labor remains controversial. Our goal was to evaluate the associations between thyroid antibodies and risk of preterm delivery by conducting a meta-analysis of prospective cohort studies.

[Clinical study of benign paroxysmal positional vertigo recurrence].

Objective: To investigate the cause of recurrence and clinical significance in benign paroxysmal positional vertigo (BPPV).

Method: By retrospectively analyzing the clinical data and results of TCD, CT or MRI of head of 65 patients with non-recurred BPPV and 44 patients with recurred BPPV in 2 years after successful canalith repositioning maneuver.

Result: The prognosis of BPPV shows significant correlated with age, family history, migraine history, intracranial arterial and carotid stenosis and stroke history.