6 results match your criteria: "People's Hospital of Danzhou[Affiliation]"
N-methyladenosine-modified circ_104797 sustains cisplatin resistance in bladder cancer through acting as RNA sponges.
Cell Mol Biol Lett
February 2024
Department of Urology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, Hainan, People's Republic of China.
Background: Bladder cancer (BCa) ranks among the predominant malignancies affecting the urinary system. Cisplatin (CDDP) remains a cornerstone therapeutic agent for BCa management. Recent insights suggest pivotal roles of circular RNA (circRNA) and N-methyladenosine (m6A) in modulating CDDP resistance in BCa, emphasizing the importance of elucidating these pathways to optimize cisplatin-based treatments.
View Article and Find Full Text PDFThe Value of Serum miR-139-3p Expression Level in Predicting Postoperative Survival of Colon Cancer Patients.
Int J Gen Med
February 2022
Department of General Surgery, People's Hospital of Danzhou, Danzhou, Hainan, People's Republic of China.
Background: To explore the value of serum miR-139-3p expression level in predicting postoperative survival of colon cancer patients.
Methods: We selected 158 cases enrolled in our hospital from January 2017 to December 2019. Using real-time fluorescence quantitative PCR, the expression extents of serum miR-139-3p among patients suffering from colon cancer were detected.
Article Synopsis
- Adriamycin (ADR) is an effective chemotherapy drug but poses a risk of heart damage, making it essential to understand how it affects heart cells (cardiomyocytes).
- Research used H9C2 cell models to examine the impact of inhibiting miR-218 and Serp1 on cell activity and apoptosis in response to ADR using various laboratory techniques.
- Findings indicate that inhibiting miR-218 protects H9C2 cells from ADR-induced damage, while suppressing Serp1 worsens cell health, revealing that miR-218 promotes heart cell apoptosis via the Serp1/p38 MAPK/caspase-3 signaling pathway.
Expression and Clinical Value of miR-185 and miR-424 in Patients with Acute Ischemic Stroke.
Int J Gen Med
January 2022
Department of Clinical Laboratory, Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, Jiangsu, People's Republic of China.
Background: To investigate the expression of serum miR-185 and miR-424 in patients with acute ischemic stroke (AIS) and their predictive value. A total of 142 patients with AIS and 50 healthy controls were enrolled.
Methods: According to the modified Rankin scale (mRS) score, AIS patients were divided into the good prognosis group and the poor prognosis group.
Expression of miR-192-5p in colon cancer serum and its relationship with clinicopathologic features.
Am J Transl Res
August 2021
Department of Pharmacy, Suzhou Xiangcheng People's Hospital Suzhou 215006, People's Republic of China.
Colon cancer has a poor prognosis due to a lack of biomarkers for early diagnosis and prognosis. The present study analyzed serum miR-192-5p expression levels in colon cancer patients and their correlations with clinicopathologic features. Relative mRNA expression was assessed by real-time fluorescence-based quantitative PCR in the serum of 164 colon cancer patients and 60 healthy controls.
View Article and Find Full Text PDF[Expression and diagnostic value of plasma miR-145 and miR-183 in children with lupus nephritis].
Zhongguo Dang Dai Er Ke Za Zhi
June 2020
Department of Pediatrics, People's Hospital of Danzhou, Danzhou, Hainan 571799, China.
Objective: To study the expression and diagnostic value of plasma miR-145 and miR-183 in children with lupus nephritis (LN).
Methods: A total of 92 children with LN who were admitted from January 2016 to May 2019 were enrolled as the LN group, among whom 17 had type II LN, 15 had type III LN, 36 had type IV LN, 18 had type V LN, and 6 had type VI LN. Forty healthy children who underwent physical examination were enrolled as the healthy control group.