1 results match your criteria: "Pennsylvania Biotechnology Center and Lankenau Institute for Medical Research[Affiliation]"
Cyclin D1-mediated microRNA expression signature predicts breast cancer outcome.
Theranostics
April 2019
Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center and Lankenau Institute for Medical Research, 100 East Lancaster Avenue, Suite, 222, Wynnewood, PA. 19096.
Genetic classification of breast cancer based on the coding mRNA suggests the evolution of distinct subtypes. Whether the non-coding genome is altered concordantly with the coding genome and the mechanism by which the cell cycle directly controls the non-coding genome is poorly understood. Herein, the miRNA signature maintained by endogenous cyclin D1 in human breast cancer cells was defined.
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