571 results match your criteria: "Penn-Presbyterian Medical Center[Affiliation]"

Objective: Over 25% of the 27 million uninsured individuals in the United States are eligible for Medicaid. Many hospitals have insurance linkage programs that assist eligible patients with enrollment, but little is known about the impact of these programs on care utilization. This research assessed health care utilization and health outcomes among patients enrolled in Medicaid via a hospital-based insurance linkage program.

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Is maxillary sinusitis and radiographic maxillary sinus opacification associated with an altered microbiology of MRONJ?

Oral Surg Oral Med Oral Pathol Oral Radiol

April 2024

Philadelphia Veterans Affairs Medical Center, Penn Presbyterian Medical Center, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA. Electronic address:

Article Synopsis
  • The study investigates the relationship between the microbiome of maxillary MRONJ (medication-related osteonecrosis of the jaw) and concurrent maxillary sinusitis, particularly focusing on the bacteria present in affected patients.
  • A retrospective analysis of 39 patients showed that a high percentage had resident or opportunistic bacteria, with those suffering from sinusitis having significantly more chronic sinusitis microbes.
  • The findings suggest that gram-positive anaerobes like Propionibacterium and the gram-negative Capnocytophaga are prevalent in MRONJ patients with sinus issues, indicating potential benefits from sinus evaluation and treatment for these individuals.
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Association between surgical quality and long-term survival in lung cancer.

Lung Cancer

April 2024

Division of Thoracic Surgery, Department of Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States.

Objectives: There are significant variations in both perioperative and long-term outcomes after lung cancer resection. While perioperative outcomes are often used as comparative measures of quality, they are unreliable, and their association with long-term outcomes remain unclear. In this context, we evaluated whether historical perioperative mortality after lung cancer resection is associated with 5-year survival.

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Effective Manuscript Preparation and Submission.

Clin Podiatr Med Surg

April 2024

Penn Presbyterian Medical Center, 3801 Filbert Streeet, Medical Office Building, Suite 111, Philadelpha, PA 19004, USA. Electronic address:

Authors have a wide range of journals to which they can submit their report for consideration for publication. One key to getting the journal editors to accept a report is that the manuscript is properly organized and in compliance with the journal's Guide for Authors. For this reason, the single most important undertaking that an author can do before submission is read the journal's Guide for Authors and make sure that the report meets the journal's requirements for publication.

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Purpose: To assess the outcome and safety of radiofrequency (RF) wire recanalization in patients with end-stage renal disease (ESRD) and chronic central venous occlusions (CVO).

Materials And Methods: A retrospective review of ESRD patients who underwent RF-wire recanalization of symptomatic chronic thoracic CVO from January 2017 to August 2022 yielded 20 patients who underwent 21 procedures. All patients had undergone at least one prior unsuccessful attempt at central venous recanalization using conventional catheter-based techniques.

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Percutaneous Management of Dialysis Access Steal Syndrome: Interventions and Outcomes from a Single Institution's 20-Year Experience.

J Vasc Interv Radiol

April 2024

Department of Radiology, Division of Interventional Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

Purpose: To determine safety and effectiveness of percutaneous interventions performed by interventional radiologists at a single institution over 2 decades in patients with dialysis access steal syndrome (DASS).

Materials And Methods: A retrospective review of fistulograms from 2001 to 2021 (N = 11,658) was performed. In total, 286 fistulograms in 212 patients with surgically created dialysis accesses met inclusion criterion of fistulography for suspected DASS.

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HIP, HIPAA, Hooray: Responding to Negative Online Reviews.

J Oral Maxillofac Surg

December 2023

Assistant Professor and Section Chief of Oral and Maxillofacial Surgery, Department of Oral and Maxillofacial Surgery, Philadelphia Veterans Affairs Medical Center, Penn Presbyterian Medical Center, University of Pennsylvania School of Dental Medicine, Philadelphia, PA. Electronic address:

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Background: Bone metastases are the most common site of metastatic disease in breast cancer and can result in significant pain and an increased risk of skeletal-related events (SREs). Uncontrolled pain can further lead to negative outcomes.

Objectives: The aim is to provide oncology nurses with the latest evidence on the management of bone metastases in metastatic breast cancer (MBC) with a focus on pain and SREs.

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Purpose: To characterize the susceptibilities of positive bacterial cultures and the appropriateness of empiric antimicrobial regimens for patients admitted from post-acute care facilities (PACFs).

Methods: This was a retrospective quality improvement study. The study included patients admitted from a PACF to one of 2 tertiary care teaching hospitals within the University of Pennsylvania Health System, located in Philadelphia, PA, from August 2020 to December 2021.

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Article Synopsis
  • - CARS (Cardiac Amyloidosis Registry Study) is a multicenter project launched in 2019 to study the natural history and treatment of cardiac amyloidosis, involving patients across the U.S. from 1997 to 2025.
  • - As of February 2023, 1415 patients have been enrolled, with 82% diagnosed with transthyretin (ATTR) and 18% with light chain (AL) amyloidosis, highlighting a diverse cohort that includes a significant portion of Black participants.
  • - The study aims to address important clinical questions about cardiac amyloidosis and improve comparisons of treatment options, with plans for future international collaboration to enhance its findings.
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Age specific reference intervals for plasma biomarkers of neurodegeneration and neurotrauma in a Canadian population.

Clin Biochem

November 2023

Djavad Mowafaghian Centre for Brain Health, University of British Columbia, 2215 Wesbrook Mall, Vancouver, British Columbia V6T 1Z3, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada; School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada; International Collaboration on Repair Discoveries, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada. Electronic address:

Introduction: In this study, we aimed to create reference intervals (RI) using a large Canadian population-based cohort, for plasma protein biomarkers with potential utility to screen, diagnosis, prognosticate and manage a variety of neurological diseases and disorders. RIs were generated for: the ratio of amyloid beta 42 over 40 (Aβ42/40), phosphorylated tau-181 (p-tau-181), neurofilament light (NfL), and glial fibrillary acidic protein (GFAP).

Methods: 900 plasma specimens from male and female participants aged 3-79 years old were obtained from the Statistics Canada Biobank, which holds specimens from the Canadian Health Measures Survey.

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Skilled nursing facilities (SNF) represent a common postdischarge destination for hospitalized older adults. The goals of SNF care include the completion of extended skilled nursing care and physical rehabilitation to enable patients to safely return home. However, nearly one in four older adults discharged to SNF are rehospitalized and one in five seek care in the emergency department (ED) but are discharged back to SNF.

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Role of Climate Change in Urologic Health: Kidney Stone Disease.

Eur Urol Focus

November 2023

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Division of Urology, Department of Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address:

Kidney stones are rising in incidence and prevalence worldwide. Given the temperature dependence of kidney stone presentations, climate change is projected to further increase the burden of disease for individuals and society. PATIENT SUMMARY: This mini-review reports current knowledge on climate change in relation to kidney stone disease.

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50-W vs 40-W During High-Power Short-Duration Ablation for Paroxysmal Atrial Fibrillation: A Multicenter Prospective Study.

JACC Clin Electrophysiol

December 2023

Cardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

Article Synopsis
  • High-power short-duration (HPSD) radiofrequency ablation is compared using 50-W and 40-W settings to see which is more effective and safer for treating atrial fibrillation (AF).
  • The study included 383 patients and measured outcomes like freedom from all-atrial arrhythmias and procedural complications over 12 months.
  • Results showed similar rates of arrhythmia-free outcomes and safety, but the 50-W group achieved quicker procedures and better first-pass pulmonary vein isolation.
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Cardiovascular Disease Burden and Outcomes Among American Indian and Alaska Native Medicare Beneficiaries.

JAMA Netw Open

September 2023

Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center, Cardiovascular Institute, University of Pennsylvania, Philadelphia.

Article Synopsis
  • * A study analyzed Medicare data from 2015 to 2019 to evaluate the incidence, prevalence, and mortality of various heart conditions among American Indian and Alaska Native patients aged 65 and older.
  • * Among the 220,598 participants, high rates of diabetes (44.8%), hyperlipidemia (61.3%), and hypertension (72.2%) were found, with evidence of worsening heart health indicators, such as an increase in myocardial infarction rates and consistent prevalence of coronary artery disease over the study period.
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Addressing Inequalities in Breast Cancer Care Delivery.

Surg Oncol Clin N Am

October 2023

Division of Breast Surgery, Department of Surgery, Hospital of the University of Pennsylvania, 3400 Spruce Street, Silverstein 4, Philadelphia, PA 19104, USA. Electronic address:

Breast cancer treatment, timeliness of care, and clinical outcomes are inferior for patients of Black race and Hispanic ethnicity, and the origin of these inequities is multifactorial. Owing to aggregate reporting of data in the United States for patients of Asian, Native Hawaiian, and Pacific Islander ancestry, disparities within and across these groups are difficult to appreciate. In large part due to low prevalence, male breast cancer remains understudied, and treatment algorithms are primarily extrapolated from research conducted in female patients.

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Objective: To assess whether measurement and feedback of chlorhexidine gluconate (CHG) skin concentrations can improve CHG bathing practice across multiple intensive care units (ICUs).

Design: A before-and-after quality improvement study measuring patient CHG skin concentrations during 6 point-prevalence surveys (3 surveys each during baseline and intervention periods).

Setting: The study was conducted across 7 geographically diverse ICUs with routine CHG bathing.

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Radiographic measurements are frequently used to classify deformity and determine treatment options. Correlation coefficients can be used to determine inter- and intrarater reliability. Reliability is a required feature of any measurement if the measurement is to provide valid information.

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Purpose: To examine the effect of end-stage renal disease (ESRD) on the likelihood of major adverse limb events (MALEs) in patients with Rutherford Category 4-6 critical limb ischemia (CLI) who underwent percutaneous vascular intervention (PVI).

Materials And Methods: Two contemporaneous cohorts of patients who underwent PVI for symptomatic CLI from 2012 to 2022, differing in ESRD status, were matched using propensity score methods. This database identified 628 patients who underwent 1,297 lower extremity revascularization procedures; propensity score matching yielded 147 patients (180 limbs, 90 limbs in each group).

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Percutaneous antegrade (anterior to posterior) fixation for subtalar joint (STJ) arthrodesis offers various intraoperative and biomechanical advantages. Currently, the entry point for percutaneous antegrade STJ screw fixation is not clearly described and variable. To our knowledge, there are no publications that evaluate anatomic structures at risk or define an anatomically safe entry point for this fixation.

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The Penn Medicine COVID-19 Therapeutics Committee-an interspecialty, clinician-pharmacist, and specialist-front line primary care collaboration-has served as a forum for rapid evidence review and the production of dynamic practice recommendations during the 3-year coronavirus disease 2019 public health emergency. We describe the process by which the committee went about its work and how it navigated specific challenging scenarios. Our target audiences are clinicians, hospital leaders, public health officials, and researchers invested in preparedness for inevitable future threats.

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