2,180 results match your criteria: "Penn State Milton S. Hershey Medical Center[Affiliation]"
Orthop J Sports Med
December 2024
Department of Orthopaedic Surgery, Johns Hopkins University, Baltimore, Maryland, USA.
Background: In professional basketball, Jones fractures are among the most common cause of lower extremity stress injury. Despite its prevalence, there is a paucity of research on the impact of Jones fractures on athletic performance in the National Basketball Association (NBA).
Purpose: To determine the impact of Jones fractures on return to play and performance among NBA players when compared with preinjury values and healthy matched controls.
J Clin Transl Sci
November 2024
Departments of Family and Community Medicine, Public Health Sciences, and Anesthesiology and Perioperative Medicine, Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
Long-term health and developmental impact after opioid and other substance exposures is unclear. There is an urgent need for well-designed, prospective, long-term observational studies. The HEALthy Brain and Child Development Study aims to address this need.
View Article and Find Full Text PDFCardiol Rev
December 2024
Department of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA.
JAMA Netw Open
November 2024
Division of Cardiology, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania.
Importance: Heart failure (HF) hospitalization is a common end point in HF trials; however, how HF hospitalization is associated with all-cause hospitalization in terms of proportionality, correlation of treatment effects, and concomitant reporting has not been studied.
Objective: To determine the ratio of HF to all-cause hospitalizations, whether reported treatment effects on HF hospitalization are associated with treatment effects on all-cause hospitalization, and how often all-cause hospitalization is reported alongside HF hospitalization.
Data Sources: PubMed was searched from inception to September 2, 2024, for randomized clinical trials (RCTs) of HF treatments using MeSH (medical subject heading) terms and keywords associated with heart failure, ventricular failure, ventricular dysfunction, and cardiac failure, as well as the names of specific journals.
Abdom Radiol (NY)
November 2024
Stanford University, Stanford, USA.
Ultrasound is the primary imaging modality used for surveillance of patients at risk for HCC. In 2017, the American College of Radiology Liver Imaging Reporting and Data Systems (ACR LI-RADS) introduced US LI-RADS to standardize the performance, interpretation, and reporting of US for HCC surveillance, with the algorithm recently updated as LI-RADS US Surveillance v2024. The American Association for the Study of Liver Diseases (AASLD) recommends reporting both the examination-level LI-RADS US Category as well as the US Visualization Score.
View Article and Find Full Text PDFNat Commun
November 2024
Department of Biomedical Engineering, Penn State University, University Park, PA, USA.
Clin Orthop Relat Res
November 2024
Department of Orthopaedic Surgery, Johns Hopkins Medicine, Columbia, MD, USA.
Background: Previously, we conducted a retrospective study of American Joint Replacement Registry (AJRR) data that examined the 2-year odds of revision between robotic-assisted and nonrobotic-assisted TKA, and we found no benefit to robotic assistance. However, proponents of robotic assistance have suggested that robot platforms confer more accurate bone cuts and precise implant sizing that might promote osteointegration of cementless implants by limiting micromotion at the bone-implant interface that could lead to aseptic loosening. Therefore, it seems important specifically to evaluate the odds of revision among patients with cementless implants only within our previous study population.
View Article and Find Full Text PDFClin Imaging
January 2025
SUNY Downstate Medical Center, Brooklyn, NY, United States of America. Electronic address:
Most physicians appreciate that practicing medicine is a commitment to continuous learning. However, "learning" can be mistakenly understood as simply the acquisition of facts and new knowledge. But learning also necessitates the constant re-examination and challenging of one's existing body of knowledge, as misinformation persists when one's beliefs are not challenged or questioned in the light of new information.
View Article and Find Full Text PDFJ Neurooncol
November 2024
Department of Neurological Surgery, Pauline Braathen Neurological Center, Cleveland Clinic Florida, Weston, FL, USA.
Intern Med J
November 2024
Department of Internal Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
Background: Abdominal paracentesis is a frequently performed procedure in hospitalised patients with ascites. Concurrently, most hospitalised adult patients receive pharmacologic anticoagulation, either for therapeutic purposes or prophylactically to prevent venous thromboembolism. Despite this, minimal evidence exists to guide management of anticoagulant therapy pre- and post-paracentesis.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
V. Zelman Institute for the Medicine and Psychology, Novosibirsk State University, Novosibirsk 630090, Russia.
Despite considerable investigative efforts, the molecular mechanisms of postoperative delirium (POD) remain unresolved. The present investigation employs innovative methodologies for identifying potential primary and secondary metabolic markers of POD by analyzing serum metabolomic profiles utilizing the genetic algorithm and artificial neural networks. The primary metabolomic markers constitute a combination of metabolites that optimally distinguish between POD and non-POD groups of patients.
View Article and Find Full Text PDFEur J Gastroenterol Hepatol
January 2025
Department of Internal Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
Metabolic-associated steatotic liver disease (MASLD) is the most common cause of chronic liver disease in Western countries, with rapidly increasing prevalence worldwide, estimated at around 40% due to modernization and urbanization. MASLD is defined as hepatic steatosis and identified through histology, imaging, blood markers, and in the absence of other secondary causes of hepatic fat accumulation, such as significant alcohol consumption, use of steatogenic medication, or hereditary disorders. The current management strategies addressing MASLD involve lifestyle modifications and treating coexisting conditions such as obesity, hyperlipidemia, insulin resistance, and type 2 diabetes.
View Article and Find Full Text PDFJ Surg Case Rep
November 2024
Division of Pediatric Surgery, Penn State Health Children's Hospital, 600 University Dr, Hershey, PA 17033, United States.
High-altitude regions pose distinctive challenges for cardiovascular health because of decreased oxygen levels, reduced barometric pressure, and colder temperatures. Approximately 82 million people live above 2400 meters, while over 100 million people visit these heights annually. Individuals ascending rapidly or those with pre-existing cardiovascular conditions are particularly vulnerable to altitude-related illnesses, including Acute Mountain Sickness (AMS) and Chronic Mountain Sickness (CMS).
View Article and Find Full Text PDFNeuro Oncol
November 2024
MacFeeters Hamilton Neuro-Oncology Program, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, ON, Canada.
Primary hyperparathyroidism (PHPT) is an endocrine disorder marked by elevated secretion of parathyroid hormone (PTH), which results in hypercalcemia and may cause complications in the kidneys and bones. Diagnosing this condition involves ruling out secondary causes and understanding the complexities of the laboratory values associated with PHPT. The disease has become more recognizable to clinicians in an earlier phase thanks to updated screening guidelines.
View Article and Find Full Text PDFCancer Prev Res (Phila)
November 2024
Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States.
While tobacco smoking is a risk factor in the development of oral squamous cell carcinoma (OSCC), only a fraction of smokers develop the disease. Compelling evidence shows that microbial community composition is associated with carcinogenesis, suggesting that the microbiome may play a role in cancer development of smokers. We previously showed that black raspberry (BRB) protects against OSCC induced by the tobacco constituent dibenzo[def,p]chrysene (DBP) altering genetic and epigenetic markers in a manner consistent with its cancer preventive activity.
View Article and Find Full Text PDFOtolaryngol Head Neck Surg
November 2024
Department of Otolaryngology-Head and Neck Surgery, Penn State Milton S. Hershey Medical Center and Penn State College of Medicine, Hershey, Pennsylvania, USA.
Objective: To assess adherence to the 2019 American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNSF) guidelines for the diagnosis and management of sudden hearing loss (SHL) and sudden sensorineural hearing loss (SSNHL).
Study Design: Retrospective cohort.
Setting: TriNetX, a de-identified healthcare database.
J Am Coll Radiol
November 2024
Specialty Chair, VA San Diego Healthcare System, San Diego, California.
J Vasc Surg
October 2024
Division of Vascular Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA.
Objective: This systematic review aims to study the available literature on the impact of SES on the surgical outcomes of peripheral artery disease (PAD), carotid artery disease, and aortic aneurysms in the United States. The review also aims to report the diverse tools used to compute SES within the vascular surgery literature.
Methods: A systematic review of English literature was conducted using the PubMed and Scopus literature databases from inception to November 2023.
J Cardiothorac Vasc Anesth
October 2024
Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Objective: To test the hypothesis that levosimendan administration in patients with low cardiac output syndrome after cardiac surgery is associated with improved long-term (5-year follow-up) outcomes.
Design: Single-center subanalysis of the multicenter randomized CHEETAH trial.
Setting: Cardiac surgery department of a tertiary hospital.
Mol Cancer Res
October 2024
Penn State College of Medicine, Hershey, PA, United States.
Future Cardiol
October 2024
Department of Internal Medicine, Penn State Milton S. Hershey Medical Center, PA 17033, USA.
Congestive Heart Failure (CHF) poses significant challenges to the healthcare system due to its high rates of morbidity and mortality as well as frequent readmissions. All of these factors contribute to increased healthcare delivery costs. Besides the burden on the healthcare system, CHF has far deeper effects on the patient in terms of psychological burden along with debilitating symptoms of dyspnea, all of which reduce quality of life.
View Article and Find Full Text PDFCancer Epidemiol Biomarkers Prev
October 2024
The Ohio State University, Columbus, OH, United States.
Background: Despite the promise of mail-based human papillomavirus (HPV) self-collection programs for increasing cervical cancer screening, few have been evaluated in the United States. We report the results of a mail-based HPV self-collection program for underscreened women living in Appalachia.
Methods: We conducted a group randomized trial during 2021-2022 in the Appalachian regions of Kentucky, Ohio, Virginia, and West Virgnia.