757 results match your criteria: "Pemphigoid Gestationis"
Evaluation Of Maternal And Fetal Findings In Patients With Pemphigoid Gestationis.
Int J Gynaecol Obstet
December 2024
Department of Obstetrics and Gynecology, Private Clinic, Kocaeli, Turkey.
Objective: To evaluate the maternal and fetal outcomes of 12 pregnant women diagnosed with pemphigoid gestationis, in conjunction with a review of the literature.
Methods: A retrospective review was conducted on the medical records of 12 patients diagnosed with pemphigoid gestationis who presented between January 2014 and January 2024.
Results: Twelve pregnant patients with pemphigoid gestationis were included in the study.
Recurrent pemphigoid gestationis in the setting of first-trimester spontaneous abortions.
JAAD Case Rep
January 2025
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.
Gestational Pemphigoid-From Molecular Mechanisms to Clinical Outcomes: A Case Report and Review of Literature.
Life (Basel)
November 2024
Department of Dermatology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Article Synopsis
Use of Intravenous Immunoglobulin in the Treatment of Pemphigoid Gestationis: A Case Report.
Cureus
October 2024
Internal Medicine and Clinical Immunology Department, Hospital San Juan de Dios, San José, CRI.
Gestational pemphigoid is a rare autoimmune skin condition specific to pregnancy and the postpartum period, with a variable course. There are currently no standardized guidelines referring to evidence-based therapeutic strategies. Intravenous immunoglobulin (IVIG) has recently emerged as a safe and effective steroid-sparing option as a second-line treatment for cases refractory to conventional steroid therapy and for managing relapses.
View Article and Find Full Text PDFCutaneous Changes During Pregnancy: A Comprehensive Review.
Cureus
September 2024
Dermatology, Venereology and Leprosy, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Article Synopsis
- Pregnancy leads to significant changes in a woman’s skin, particularly on the face and trunk, due to hormonal, mechanical, and immune factors.
- Common skin alterations during this time include hyperpigmentation, stretch marks, and various vascular changes, along with potential issues like skin tags and other specific conditions.
- Understanding these changes is crucial for healthcare providers to offer proper support and management for expectant mothers, improving clinical care and paving the way for future research.
["Red flags" during pregnancy-skin symptoms and their causes during pregnancy].
Dermatologie (Heidelb)
November 2024
Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Haus C, 24105, Kiel, Deutschland.
Article Synopsis
- - Pregnancy causes significant physical changes in a woman's body, particularly affecting the skin, making it essential for healthcare providers to understand various pregnancy-related skin issues.
- - The article outlines key skin changes during pregnancy, highlighting altered pigmentation and the effects on existing inflammatory skin conditions, including their potential improvement or worsening.
- - It also discusses specific pregnancy dermatoses and the implications of maternal autoimmune diseases on the unborn child, emphasizing the importance of recognizing warning signs or "red flags" for proper diagnosis and care.
Perinatal Outcome of Pemphigoid Gestationis: A Report of Three Cases and Review of the Literature.
Cureus
September 2024
Department of Obstetrics and Gynecology, Shiga University of Medical Science, Ostu, JPN.
Article Synopsis
- Pemphigoid gestationis (PG) is a rare autoimmune skin condition that appears during pregnancy, often causing itchy blisters due to the immune system attacking a specific protein in the skin.
- This report details three unique cases of PG, highlighting different symptoms, treatments, and delivery methods: a 32-year-old woman treated with oral prednisone, a 37-year-old woman who improved with topical steroids, and a 35-year-old woman who required an emergency cesarean section due to fetal concerns.
- The cases indicate that PG can vary greatly in its presentation and impact on pregnancy, emphasizing the need for early diagnosis and tailored treatment plans to ensure the best results for mothers and babies.
Pemphigoid gestationis after egg donation: A case report and literature review.
J Dtsch Dermatol Ges
November 2024
Department of Dermatology, Kurume University School of Medicine, Fukuoka, Japan.
Placental pathology abnormalities in pemphigoid gestationis.
Arch Dermatol Res
August 2024
Harvard Medical School, Boston, MA, USA.
Pemphigoid gestationis is associated with an increased risk for adverse pregnancy outcomes: A large-scale propensity-matched retrospective cohort study.
J Am Acad Dermatol
October 2024
Department of Dermatology, University Medical Center of the State of Schleswig-Holstein (UKSH), Campus Lübeck, Lübeck, Germany; Lübeck Institute of Experimental Dermatology, University of Lübeck, Lübeck, Germany.
State-of-the-art diagnosis of autoimmune blistering diseases.
Front Immunol
June 2024
Department of Dermatology, Allergology and Venerology, University of Lübeck, Lübeck, Germany.
Article Synopsis
- - Autoimmune blistering disorders (AIBDs) include various conditions such as pemphigus and pemphigoid, characterized by blisters and skin lesions that can have diverse appearances, making accurate diagnosis essential for treatment and prognosis.
- - Diagnosis typically combines clinical evaluation with the detection of specific autoantibodies, utilizing tests like enzyme-linked immunosorbent assay (ELISA) and direct immunofluorescence microscopy (IFM), which is considered the gold standard.
- - Recent advancements in molecular identification of target antigens have led to new diagnostic methods and treatment approaches, enhancing the ability to detect specific antibodies related to various AIBDs.
Diagnostic Utility of Direct Immunofluorescence on Paraffin-Embedded Skin Biopsy Samples for the Diagnosis of Autoimmune Vesiculobullous Lesions.
Cureus
March 2024
Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Article Synopsis
- Autoimmune vesiculobullous diseases (AIBDs) are characterized by skin blisters caused by autoantibodies, and the gold standard diagnostic test is direct immunofluorescence (DIF) on fresh-frozen tissue.
- This study compared DIF using paraffin-embedded tissue (PE-DIF) to fresh-frozen tissue (FF-DIF) in 30 AIBD cases, finding that PE-DIF can detect similar patterns, particularly in pemphigus vulgaris and pemphigus foliaceous, although results can vary in intensity.
- The research concluded that while PE-DIF can supplement diagnosis in situations where frozen tissues are unavailable, it tends to deteriorate faster than FF-DIF and should
Pregnancy-associated blistering in a patient with junctional epidermolysis bullosa.
JAAD Case Rep
April 2024
Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Do We Need to Monitor for Graves' Disease After a Diagnosis of Pemphigoid Gestationis?
Cureus
November 2023
Dermatology, Temple University Hospital, Philadelphia, USA.
Article Synopsis
- Pemphigoid gestationis (PG) is a rare autoimmune skin condition that occurs during pregnancy or shortly after childbirth.
- There may be a connection between PG and Graves' disease, but the evidence is inconsistent, with previous studies often finding that Graves' disease was diagnosed before PG.
- More research is needed, especially long-term studies, to understand the lifetime risk of developing Graves' disease in women who have experienced PG.
Pemphigoid gestationis and polymorphic eruption of pregnancy: treatment and outcomes in a retrospective cohort study.
Int J Dermatol
January 2024
Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
Case Report: The many faces of bullous pemphigoid.
Front Immunol
October 2023
Department of Dermatology, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Article Synopsis
- - The pemphigoid group includes several skin diseases characterized by autoantibodies that target components of the basement membrane, causing blister formations and symptoms like itching and erythema.
- - Bullous pemphigoid is the most common type and usually occurs in older individuals, but cases can arise in younger people as well, often linked to factors like vaccination or pregnancy.
- - The text discusses four specific cases of younger patients with anti-BP180 antibodies, highlighting the need for personalized treatment strategies due to their unique clinical presentations and underlying causes.
[Rare variants of pemphigoid diseases].
Dermatologie (Heidelb)
December 2022
Klinik für Dermatologie, Allergologie und Venerologie, Universität zu Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Deutschland.
Article Synopsis
- * There has been a notable increase in cases of these diseases, connected to an aging population and advancements in diagnostic techniques and understanding of the conditions.
- * Key types of pemphigoid, including bullous pemphigoid and mucous membrane pemphigoid, are widely recognized, but rarer variants are emerging, highlighting the need for precise diagnosis and tailored treatment options despite the lack of clinical trial data.
Pemphigoid gestationis treated with dupilumab.
JAAD Case Rep
November 2023
Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
Biologic therapy for refractory pemphigoid gestationis: An evidence-based systematic review.
JAAD Int
December 2023
Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
A Case of Neonatal Alloimmune Thrombocytopenia Following Maternal Pemphigoid Gestationis.
Cureus
September 2023
Pediatrics, Baptist Health, Jacksonville, USA.
Article Synopsis
- - Neonatal alloimmune thrombocytopenia (NAIT) occurs when a mother’s antibodies pass through the placenta and attack the platelets of her fetus, leading to complications like inadequate weight gain in the baby.
- - A reported case showed severe NAIT that improved after treatment with platelet products and intravenous immunoglobulin (IVIG), revealing a link to the mother's history of gestational pemphigus.
- - The study emphasizes the need to understand how maternal autoimmune conditions, like pemphigoid gestationis (PG), can affect fetal health and highlight the complex interactions between these conditions.
New-Onset Pemphigoid Gestationis Following COVID-19 Vaccination.
Cutis
May 2023
Emory University School of Medicine, Atlanta, Georgia. Drs. Huffaker and Feldman are from the Department of Dermatology.
Use of a pregnancy dermatology clinical scoring system to differentiate between pemphigoid gestationis and polymorphic eruption of pregnancy: practical considerations for the obstetrician.
Am J Obstet Gynecol MFM
September 2023
Departments of Dermatology and Laboratory Medicine and Pathology, Mayo Clinic, 200 1st St. SW, Rochester, MN 55905. Electronic address:
A case of intractable pemphigoid gestationis that was prolonged after delivery and caused blisters in the neonate.
Postepy Dermatol Alergol
April 2023
Department of Dermatology, Jichi Medical University Saitama Medical Center, Saitama, Japan.