7 results match your criteria: "Peking University Sixth Hospital and Peking University Institute of Mental Health[Affiliation]"
Gender differences in the association between childhood maltreatment and the onset of major depressive disorder.
J Affect Disord
April 2024
Department of Pharmacology and Tianjin Key Laboratory of Inflammatory Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China. Electronic address:
Background: Childhood maltreatment is widely acknowledged as a risk factor for developing major depressive disorders (MDDs) in adulthood. However, the influence of gender on age at MDD onset and the relationships between various forms of maltreatment remain unclear.
Aims: This study aimed to evaluate the effect of gender on the relationship between childhood maltreatment and depressive disorder onset with regard to maltreatment severity, age at onset, and the correlation between different forms of maltreatment.
Information-based multivariate decoding reveals imprecise neural encoding in children with attention deficit hyperactivity disorder during visual selective attention.
Hum Brain Mapp
February 2023
State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in school-age children. Attentional orientation is a potential clinical diagnostic marker to aid in the early diagnosis of ADHD. However, the underlying pathophysiological substrates of impaired attentional orienting in childhood ADHD remain unclear.
View Article and Find Full Text PDFTranscranial alternating current stimulation for treating depression: a randomized controlled trial.
Brain
March 2022
Division of Neuropsychiatry and Psychosomatics, Department of Neurology, Beijing Psychosomatic Disease Consultation Center, Xuanwu Hospital, National Center for Neurological Disorders, National Clinical Research Center for Geriatric Diseases, Capital Medical University, Beijing 100053, China.
Treatment of depression with antidepressants is partly effective. Transcranial alternating current stimulation can provide a non-pharmacological alternative for adult patients with major depressive disorder. However, no study has used the stimulation to treat first-episode and drug-naïve patients with major depressive disorder.
View Article and Find Full Text PDFIdentification of Key Genes and the Pathophysiology Associated With Major Depressive Disorder Patients Based on Integrated Bioinformatics Analysis.
Front Psychiatry
April 2020
Key Laboratory of Mental Health, Ministry of Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University Sixth Hospital and Peking University Institute of Mental Health, Beijing, China.
At present, laboratory blood tests to support major depressive disorder (MDD) diagnosis are not available. This study aimed to screen potential mRNAs for peripheral blood biomarkers and novel pathophysiology of MDD. The present study utilized public data from two mRNA microarray datasets to analyze the hub genes changes related to MDD.
View Article and Find Full Text PDFPrevalence and clinical features of atypical depression among patients with major depressive disorder in China.
J Affect Disord
March 2019
Key Laboratory of Mental Health, Ministry of Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University Sixth Hospital and Peking University Institute of Mental Health, Beijing 100191, China. Electronic address:
Article Synopsis
- This study examined the prevalence and characteristics of atypical depression among major depressive disorder (MDD) patients in China, finding that 15.3% of patients had atypical features.
- Atypical depression patients were more likely to experience severe symptoms, such as suicidal ideation, psychotic features, and seasonal episodes, and generally had an earlier onset of depression.
- The study's limitation includes not using a validated scale to assess atypical features, but it highlights that atypical depression may be more severe and impactful in Chinese MDD patients.
Genetic variations in the ADCK1 gene predict paliperidone palmitate efficacy in Han Chinese patients with schizophrenia.
J Neural Transm (Vienna)
January 2019
Peking University Sixth Hospital and Peking University Institute of Mental Health and Key Laboratory of Mental Health, Ministry of Health (Peking University) and National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Beijing, 100191, China.
Genome-wide association study results have linked ADCK1 genetic variation with paliperidone efficacy in a European cohort. However, the generalizability of this locus to non-European populations is unknown. Han Chinese schizophrenia patients (n = 159) were treated with paliperidone palmitate and symptom severity was assessed over 3 months.
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