The study examined clinical and pathological features in 186 Chinese patients with renal immunoglobulin light-chain amyloidosis (AL) over 21 years.
The researchers found that the amount of amyloid deposits in the kidneys correlated with proteinuria levels and renal insufficiency, with certain patterns linked to heart and liver involvement.
The findings highlighted differences between AL-κ and AL-λ types and established that a higher renal amyloid load increases the risk of overall mortality.