1 results match your criteria: "Peking Union Medical College Tianjin 300192 P. R. China wangzhongyan@irm-cams.ac.cn.[Affiliation]"
The substitution of a single amino acid with its enantiomer for control over the adjuvant activity of self-assembling peptides.
RSC Adv
April 2020
Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Peking Union Medical College Tianjin 300192 P. R. China
The substitution of a single amino acid with its enantiomer may lead to variations in self-assembled nanostructures and biological functions. In this study, we reported three novel heterochiral peptide hydrogels, Nap-GFFY (gel-1), Nap-GFFY (gel-2) and Nap-GFFY (gel-3), from Nap-GFFY the substitution of a single amino acid with its enantiomer. We found that the resulting hydrogels possessed diverse self-assembly behaviors and adjuvant activities.
View Article and Find Full Text PDF