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Characterization of renal injury in non-squamous non-small cell lung cancer patients treated with pemetrexed: A single-center retrospective study.
Thorac Cancer
December 2024
Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College Hospital College, Chinese Academy of Medical Sciences, Beijing, China.
Article Synopsis
- * A study of 136 patients revealed a 31.6% incidence of renal injury, with older age, cisplatin use, and more treatment cycles increasing risk; some patients had to discontinue pemetrexed due to low kidney function.
- * Despite renal injury, the overall survival rates were similar for patients with and without kidney issues, highlighting the need for ongoing kidney monitoring during pemetrexed treatment.