2,405 results match your criteria: "Pediatrics Febrile Seizures"
Favorable outcomes and FDG-PET changes following tocilizumab treatment for febrile infection-related epilepsy syndrome in a child.
Int Immunopharmacol
December 2024
Department of Pediatrics, the First Medical Centre, Chinese PLA General Hospital, Beijing, China; Senior Department of Pediatrics, the Seventh Medical Center of PLA General Hospital, Beijing, China; Medical School of Chinese People's Liberation Army, Beijing, China. Electronic address:
Febrile Infection-Related Epilepsy Syndrome (FIRES) is an infrequent yet severe form of epilepsy that rapidly evolves into status epilepticus following a febrile episode. Prompt diagnosis coupled with effective treatment strategies is critical for improving patient outcomes. Herein, we describe the case of an 11-year-old male with FIRES who was successfully treated with tocilizumab, resulting in no further seizures or residual disability.
View Article and Find Full Text PDFDyke-Davidoff-Masson syndrome - A dainty spectrum with a diligent diagnosis.
J Family Med Prim Care
October 2024
Department of Paediatrics, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, Tamil Nadu, India.
Article Synopsis
Status Epilepticus in Children: Risk Factors and Clinical Evaluation.
Tunis Med
November 2024
Pediatrics and Neonatology department, Yasminette Ben Arous. University El Manar, Faculty of Medecine of Tunis, Tunisia.
Article Synopsis
Evaluation of Febrile Seizures Focusing on the Diurnal Variation.
Cureus
October 2024
Department of Pediatrics, Haibara General Hospital, Shizuoka, JPN.
Article Synopsis
Risk factors of seizure and complex seizure in febrile children: a clinical study.
BMC Pediatr
November 2024
Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Article Synopsis
Complex Febrile Seizures: Usual and the Unusual.
Indian J Pediatr
January 2025
Epilepsy Program, Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, M5G 1X8, Canada.
Article Synopsis
Frequency and characteristics of seizures precipitated by febrile urinary tract infections in neonates and infants.
Pediatr Neonatol
October 2024
Department of Pediatrics, Chonnam National University Medical School, Gwangju, South Korea; Department of Pediatrics, Chonnam University Children's Hospital, Gwangju, South Korea. Electronic address:
Article Synopsis
Clinical characteristics of severe influenza as a risk factor for febrile seizures in children: a retrospective analysis.
Front Pediatr
October 2024
Pediatric Emergency Department, Henan Children's Hospital Zhengzhou Children's Hospital, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan Province, China.
Article Synopsis
Acute necrotizing encephalopathy in an infant: A case report.
Radiol Case Rep
January 2025
Department of Paediatrics and Child Health, Aga Khan Hospital Tanzania, Dar Es Salaam 2289, Tanzania.
Article Synopsis
- - Acute necrotizing encephalopathy (ANE) is a rare and severe brain condition that causes symmetrical damage to areas like the thalamus and cerebellum, often leading to serious symptoms.
- - A case study describes a 10-month-old girl who experienced multiple seizures after a short fever and was diagnosed through MRI showing typical brain abnormalities associated with ANE.
- - Treatment focuses on managing symptoms, with high-dose steroids and IVIG sometimes used; recognizing ANE early is crucial for better health outcomes.
Clinical Significance of Lumbar Puncture in Children with First Febrile Seizures.
Iran J Child Neurol
September 2024
Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Korea.
Article Synopsis
Investigating the effect of polygenic background on epilepsy phenotype in 'monogenic' families.
EBioMedicine
November 2024
Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia. Electronic address:
Article Synopsis
- The study investigated how polygenic risk factors influence the severity and occurrence of epilepsy within families that have a known genetic cause, particularly focusing on families with genetic epilepsy with febrile seizures plus (GEFS+).
- Researchers analyzed data from 304 individuals, finding that a higher polygenic risk score (PRS) was linked to a greater likelihood of an epilepsy diagnosis and was associated with more severe epilepsy phenotypes.
- The results suggest that the genetic background can modify how rare pathogenic variants express themselves in terms of disease severity, highlighting the role of polygenic risk in understanding familial epilepsy.
Evaluation of Neutrophil Gelatinase-Associated Lipocalin Levels in Children With Febrile Seizures: A Case-Control Study.
Clin Pediatr (Phila)
October 2024
Department of Pediatrics, Faculty of Medicine, Sohag University, Sohag, Egypt.
Article Synopsis
Recessive Variants in PIGG Cause a Motor Neuropathy with Variable Conduction Block, Childhood Tremor, and Febrile Seizures: Expanding the Phenotype.
Ann Neurol
October 2024
Centre for Neuromuscular Diseases, Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London, UK.
Article Synopsis
Febrile Seizures, Ongoing Epileptiform Activity, and the Resulting Long-Term Consequences: Lessons From Animal Models.
Pediatr Neurol
December 2024
Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Department of Cell Biology and Anatomy, University of Calgary, Calgary, AB, Canada. Electronic address:
Article Synopsis
Developmental and epileptic encephalopathy 56 due to YWHAG variants: 12 new cases and review of the literature.
Eur J Paediatr Neurol
November 2024
Movement Disorders Unit, Pediatric Neurology Department, Institut de Recerca, Hospital Sant Joan de Déu Barcelona, Barcelona, Spain; European Reference Network for Rare Neurological Diseases (ERN-RND), Barcelona, Spain; U-703 Centre for Biomedical Research on Rare Diseases (CIBER-ER), Instituto de Salud Carlos III, Barcelona, Spain. Electronic address:
Article Synopsis
Development and validation of a nomogram for the estimation of the prognosis of patients presenting with a febrile seizure.
BMC Pediatr
October 2024
Department of Pediatrics, Qilu Hospital of Shandong University, No.107 West Wenhua Road, Jinan, Shandong Province, 250012, China.
Article Synopsis
- Febrile seizures are common in young children and can lead to epilepsy, affecting their health and development, so this study aimed to create a predictive tool to assess the risk of this transition.
- Researchers analyzed data from 306 pediatric patients to identify key clinical factors associated with the risk of developing epilepsy after febrile seizures, utilizing various statistical methods.
- The resulting predictive nomogram, based on five significant factors, showed strong accuracy in risk assessment, helping doctors make better treatment decisions for children experiencing febrile seizures.
Clinical characteristics and serum 25-hydroxyvitamin D levels in children with febrile seizures in China.
Sci Rep
October 2024
Department of Pediatrics, Children Hematological Oncology and Birth Defects Laboratory, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan, People's Republic of China.
Article Synopsis
- The study looked at vitamin D levels in children with febrile seizures in Luzhou, China, comparing them to healthy kids.
- It found that kids with seizures had lower vitamin D levels and that older kids had even less vitamin D.
- The researchers suggested that getting more vitamin D through supplements and spending time outside could help prevent seizures in children.
Etiological Profile of First Episode Seizures in Paediatric Patients at a Tertiary Care Centre: A Descriptive Cross-sectional Study.
JNMA J Nepal Med Assoc
March 2024
Nepal Medical College Teaching Hospital, Jorpati, Kathmandu, Nepal.
Article Synopsis
- Seizures are the most common emergency for kids and this study looks at kids in Eastern Nepal who had their first seizure.
- The study included 170 children, mostly boys, and most of them were younger than 5 years old, with fever being the most common symptom when they had seizures.
- The main causes of these seizures were febrile seizures (from fever), neurocysticercosis (a type of infection), and meningitis, and doctors used different tests to figure out what's causing the seizures.
[Pre-hospital and hospital treatment of febrile seizures].
Rev Neurol
October 2024
Institut de Recerca Biomèdica Lleida, Lleida, España.
Article Synopsis
- Febrile seizures are common reasons why kids go to the hospital, and this study looks at how to better treat them since there are no clear guidelines, especially for complex febrile seizures.
- The study included 266 children who had febrile seizures at a hospital and found that most seizures were simple, with many patients receiving treatment before arriving at the hospital.
- The researchers discovered that many tests were done on these patients, even when the cause of the fever was found, suggesting that not every test is necessary for every child.
SMS-Based Active Surveillance of Adverse Events following Immunization in Children: The VigiVax Study.
Vaccines (Basel)
September 2024
Section of Pharmacology, Department of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Article Synopsis
- The study looked at how well using text messages (SMS) can help track side effects from vaccines compared to older methods.
- Parents of young children were asked about any problems after their kids got vaccinated, and responses were collected and checked for accuracy.
- Results showed that most side effects were not serious, and the study suggested that using digital methods like SMS can help improve reporting about vaccine safety.
Ultrastructural Analysis of the Large Neuronal Perikarya in an Injured Dentate Nucleus Using an Experimental Model of Hyperthermia-Induced Convulsions: The First Qualitative and Quantitative Study.
J Clin Med
September 2024
Department of Medical Pathomorphology, Faculty of Medicine with the Division of Dentistry and Division of Medical Education in English, Medical University of Bialystok, 15-269 Białystok, Poland.
Article Synopsis
- Febrile seizures are a common type of convulsion in kids, and this study aims to understand how they happen by looking closely at brain cells in rats.
- The researchers heated the rats to make them have seizures, then used special microscopes to see what happened to the brain cells.
- They found that the brain cells showed serious damage when the rats were heated, which could help scientists find ways to prevent seizures in children in the future.
Expanding the Spectrum of Autosomal Dominant -Related Disease: Case Report and Literature Review.
Genes (Basel)
September 2024
Pediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Article Synopsis
- Developmental and epileptic encephalopathies (DEE) are disorders that can be caused by new mutations in a specific gene, leading to different symptoms, from severe conditions to milder ones like autism.
- A case study of a six-year-old boy showed he had a new mutation in that gene, but he did not develop epilepsy and had a normal brain scan over five years.
- This case helps us understand that not everyone with mutations in this gene will have serious problems, which is important for doctors to know when diagnosing developmental delays.
Case report: Epilepsy during the use of recombinant human growth hormone: a report on two cases and a literature review.
Front Pharmacol
September 2024
Department of Pediatrics, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, China.
Article Synopsis
- The text talks about two boys in China who had epilepsy while taking a treatment called recombinant human growth hormone (rhGH).
- The first boy had a history of convulsions but his epilepsy was controlled after stopping rhGH and starting medication.
- The second boy showed signs of epilepsy after starting treatment but didn’t feel better when one of his other medications was stopped.
Risk factors for secondary epilepsy following febrile seizures in children: A meta-analysis.
Epilepsy Behav
December 2024
Department of Pediatrics, First Affifiliated Hospital of Hebei Medical University, Hebei Medical University, Shijiazhuang 050000, China. Electronic address:
Article Synopsis
- The objective of the study was to find out what factors can increase the risk of children developing epilepsy after having febrile seizures.
- Researchers looked at many studies and analyzed data from 23 different research articles involving over 5,000 children.
- The results showed that several factors like having multiple seizures, a family history of epilepsy, and other medical issues can increase the risk, while being female didn’t really matter.