1,386 results match your criteria: "Pediatric Sinusitis Medical Treatment"

Background: Group A Streptococci (GAS) may cause infections of the pharynx and soft tissues and invasive infections in children (iGAS). A significant increase in severe iGAS infections has been reported in Europe since the fall of 2022.

Objectives: This retrospective study aims to analyse clinical data of children with invasive and non-invasive GAS infections in the post-COVID-19 pandemic era, searching for predisposing factors to developing invasive infections.

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Background: Recurrent infections of the nose, sinuses and ears are common problems for people with primary ciliary dyskinesia. While pulmonary exacerbations in primary ciliary dyskinesia are defined, there is no definition for ear-nose-throat exacerbations, a potential outcome for research and clinical trials.

Methods: We set up an expert panel of 24 ear-nose-throat specialists, respiratory physicians, other healthcare professionals and patients to develop consensus definitions of sinonasal and otological exacerbations in children and adults with primary ciliary dyskinesia for research settings.

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Background: Ensuring antibiotics are prescribed only when necessary is crucial for maintaining their effectiveness and is a key focus of public health initiatives worldwide. In cases of sinusitis, among the most common reasons for antibiotic prescriptions in children, healthcare providers must distinguish between bacterial and viral causes based on clinical signs and symptoms. However, due to the overlap between symptoms of acute sinusitis and viral upper respiratory infections, antibiotics are often over-prescribed.

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Pediatric chronic sinusitis (CRS) is a common disease within the field of otolaryngology-head and neck surgery. Due to the immaturity of sinus development and immune competence in children, its etiology and pathophysiology are complex, and its clinical features and outcomes differ significantly from those in adult patients. Currently, there are issues in the diagnosis and treatment of pediatric CRS, particularly in areas such as antibiotic use and surgical interventions, owing to a lack of sufficient attention.

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Subperiosteal Abscess of the Orbit: Long-term Trends in Bacteriology and Clinical Outcomes and Current Management Recommendations.

Ophthalmic Plast Reconstr Surg

November 2024

Division of Oculofacial and Orbital Surgery, Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.

Purpose: To evaluate the impact over time of evolving upper respiratory pathogens, modified microbial terminology, and improved laboratory isolation on the bacteriology and management of sinusitis-related subperiosteal abscess of the orbit.

Methods: Comparative case series of pediatric patients with bacterial sinusitis-related subperiosteal abscess from 2012 to 2022. Outcomes, culture results, age-specific findings, and antibiotic duration were compared with those in 1977 to 1992, 1988 to 1998, 1999 to 2008, and 2002 to 2012 cohorts at the same institution.

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Article Synopsis
  • Intracranial suppurative infections in kids, though rare, can lead to high mortality, making early diagnosis and treatment critical; nine severe cases requiring surgery were noted in a recent cluster.
  • The study employed statistical methods like Cramer's V effect size and Fisher's exact test to analyze clinical features, revealing significant associations among symptoms and pathogens.
  • Findings indicate notable connections, such as sinusitis linked to Streptococcus pyogenes, and aim to improve clinical management of pediatric intracranial abscesses by identifying specific patterns in these cases.
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Orbital abscesses secondary to odontogenic infections are rare but can lead to serious complications, including compressive optic neuropathy and permanent vision loss, if not diagnosed and treated promptly. We present the case of a 13-year-old child with a radiologically confirmed orbital abscess associated with a recent odontogenic infection. The patient initially presented with a one-week history of right eyelid swelling and fever.

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Unlabelled: Rehabilitation of children with fractures of the upper wall of the maxillary sinus remains relevant due to the need for a balanced approach to treatment, which would take into account both the features of traumatic injuries in children and the specifics of their age development. The article describes a technique for combined (endoscopic transnasal and transconjunctival) surgical treatment of children with fractures of the upper wall of the maxillary sinus using a sinus balloon catheter.

Objective: To study the effectiveness and safety of the functional method of treating fractures of the upper wall of the maxillary sinus using endoscopic sinus surgery and a sinus balloon catheter.

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: Brain imaging studies in pediatric patients with headaches often reveal inflammation of the sphenoid sinus. When we encounter patients presenting with headaches without respiratory symptoms, determining the causal relationship between isolated sphenoid sinusitis observed in brain imaging studies and headache is challenging. This study aims to evaluate the clinical characteristics of pediatric patients with headaches and isolated sphenoid sinusitis identified by brain imaging studies and to determine the effects of antibiotics on headache relief.

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The Future of Odontogenic Sinusitis.

Otolaryngol Clin North Am

December 2024

Otolaryngology Unit, Department of Health Sciences, Santi Paolo and Carlo Hospital, Università degli Studi di Milano, Milan, Italy. Electronic address: https://twitter.com/ent_ams.

This article discusses the exciting future of odontogenic sinusitis (ODS) in the context of recent advancements in ODS understanding. It emphasizes the importance of integrating ODS into the broader framework of sinonasal diseases and highlights the need for multidisciplinary collaboration among otolaryngologists and dental specialists to optimize clinical outcomes, research, and education. Key challenges include refining dental and sinus pathophysiologic understandings, establishing widely accepted diagnostic criteria, and optimizing multidisciplinary treatment pathways.

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Article Synopsis
  • Azithromycin is used to treat various infections in children but may cause liver damage, and its exact action mechanism is unknown.
  • The study aimed to understand the molecular basis of azithromycin-induced liver injury to improve treatment strategies.
  • Findings reveal that azithromycin leads to increased liver cell death and oxidative stress, and its harmful effects may stem from the suppression of protective pathways in the liver.
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Evaluation and treatment of rhinosinusitis with primary antibody deficiency in children: Evidence-based review with recommendations.

Int Forum Allergy Rhinol

November 2024

Section of Otolaryngology-Head and Neck Surgery, The University of Chicago Medicine, The Comer Children's Hospital, Chicago, Illinois, USA.

Background: There is clear evidence that prevalence of primary antibody deficiency (PAD) is higher in children with chronic rhinosinusitis (CRS) than in the general population. The purpose of this multi-institutional and multidisciplinary evidence-based review with recommendations (EBRR) is to thoroughly review the literature on rhinosinusitis with PAD, summarize the existing evidence, and provide recommendations on the evaluation and management of rhinosinusitis in children with PAD.

Methods: The PubMed, Embase, and Cochrane databases were systematically reviewed from inception through December 2023.

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Chronic Osteomyelitis Following Foreign Body Entrapment in Pediatric Mandible-a Case Reprt.

Indian J Otolaryngol Head Neck Surg

October 2024

Department of Burns, Plastic and Maxillofacial Surgery, VMMC and Safdarjung hospital, New Delhi, India.

Article Synopsis
  • - Chronic osteomyelitis in kids, often caused by foreign objects like nails in the mandible, can lead to serious issues such as pus discharge and infection.
  • - A case study highlighted a 12-year-old boy who had an iron nail embedded near a decayed tooth, which was found using radiographic imaging.
  • - Effective treatment and good healing were achieved, underscoring the importance of preventive measures, including parent education and teamwork among healthcare professionals.
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In this study, we aimed to follow up on the surprising increase in the incidence of orbital subperiosteal abscesses (SPA) reported in the Iranian pediatric population in the post-COVID era. Pediatric patients (≤ 18 years old) diagnosed with orbital SPA following acute sinusitis who were hospitalized between October 1st, 2023, and March 31st, 2024 in Farabi Eye Hospital, Tehran, Iran, were included. Demographic, clinical, microbiologic, and radiological characteristics of patients were reviewed.

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Article Synopsis
  • Cornelia de Lange syndrome (CdLS) is a rare genetic disorder that often comes with various issues related to the ears, nose, and throat, including a higher rate of conditions like chronic rhinosinusitis (CRS) and chronic rhinosinusitis with nasal polyps (CRSwNP).
  • A literature review and a case study of an 8-year-old boy with CdLS and CRSwNP revealed that traditional medical treatments were ineffective, leading to successful surgical intervention for his nasal obstruction.
  • Additional research indicates that CRSwNP is more common among CdLS patients compared to the general population, and suggests that a combination of medical and surgical approaches can effectively manage this condition.
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Isolated external jugular thrombophlebitis secondary to acute pharyngitis: a case report and a review of the literature.

Ital J Pediatr

September 2024

Division of Pediatric Otolaryngology, Department of Otolaryngology Head and Neck Surgery, NYU Langone Health, 240 East 38th Street 14th floor, New York, NY, 10016, USA.

Article Synopsis
  • External Jugular Thrombophlebitis (EJT) is a rare condition, especially in children, and this case report discusses a 13-year-old with right-sided EJT linked to acute pharyngitis and left-sided sinusitis.
  • The patient presented with worsening upper respiratory symptoms, facial swelling, and was diagnosed with sinusitis and external jugular vein thrombosis after imaging was conducted.
  • The treatment included IV antibiotics and anticoagulation, leading to improvement, and follow-up showed no recurrence of EJT, highlighting the importance of recognizing EJT symptoms in conjunction with respiratory infections.
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Background: Acute rhinosinusitis (ARS) is a self-limiting inflammation of the nose and sinuses caused by viral or bacterial infections that requires primarily symptomatic treatment. Patient-reported outcome measures (PROMs) are suitable tools for the assessment of the effectiveness of remedies for ARS from the patient's perspective in clinical trials and real-world studies. Data regarding the quality of existing PROMs for ARS are limited.

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Article Synopsis
  • * It emphasizes that extra pulmonary tuberculosis can present in unusual ways, which might lead to misdiagnosis if not considered in the differential diagnosis, especially in the bones of the limbs.
  • * The report highlights the need for vigilance among clinicians, as conditions like Enchondromatosis or Chronic pyogenic osteomyelitis can resemble this rare presentation, despite a significant decrease in such cases due to advances in anti-tubercular therapy.
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The evidence base for the optimal antibiotic treatment duration of upper and lower respiratory tract infections: an umbrella review.

Lancet Infect Dis

September 2024

Department of Internal Medicine, Division of Infectious Diseases, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands. Electronic address:

Article Synopsis
  • An umbrella review was conducted to evaluate existing evidence on optimal antibiotic treatment durations for various respiratory tract infections, focusing on whether shorter courses are as effective as longer ones.
  • The review included systematic reviews of conditions like community-acquired pneumonia and acute sinusitis, assessing factors like clinical outcomes and the quality of the studies using established criteria.
  • Findings indicated that most systematic reviews were of low quality, but there was some support for a 5-day treatment duration for community-acquired pneumonia and acute exacerbation of chronic obstructive pulmonary disease; however, reliable evidence for other conditions and shorter durations is lacking.
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Imaging features of pediatric angiosarcomas: clinical, pathologic, and radiological review.

Pediatr Radiol

October 2024

Department of Diagnostic and Interventional Radiology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada.

Article Synopsis
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Langerhans cell histiocytosis in sphenoid sinus with vision impairment: Case report and literature review.

Sci Prog

August 2024

Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Langerhans cell histiocytosis (LCH) is a neoplastic disease characterized by aberrant proliferation of the mononuclear phagocyte system, predominantly affecting children under the age of 3 years. Although LCH can affect almost all organs, sinus involvement is rare. This case report documents a 9-year-old boy presented with vision impairment and intermittent headache on the right side.

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Pneumocephalus is uncommon, mostly arising as a result of surgery, trauma, infection, or neoplasm. Spontaneous occurrence is extremely rare and few case studies have been published. Pneumocephalus may also present as a complication of sinusitis and is a potential emergency.

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