106 results match your criteria: "Pediatric Heart Centre[Affiliation]"

Primary transcatheter dilation of the pulmonary valve in cyanotic patients with tetralogy of Fallot and dominant pulmonary valve stenosis.

Front Cardiovasc Med

November 2024

Cardiac Catheterization Laboratories, Department of Pediatric Cardiology, German Pediatric Heart Centre, University Hospital Bonn, Bonn, Germany.

Article Synopsis
  • * A retrospective analysis of 19 patients showed significant improvement in blood oxygen saturation after PVB, with many experiencing positive changes in pulmonary valve and artery measurements, although some faced recurrent desaturation requiring further interventions.
  • * The findings suggest that PVB is a safe and effective early palliative measure for managing cyanosis in TOF patients, allowing for improved pulmonary development and delaying the need for more invasive surgical repairs, with BRCTs not significantly altering surgical approaches.
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Double aortic arch with an atretic left aortic arch can resemble like a right aortic arch with an aberrant left subclavian artery or a right aortic arch with mirror image branching. Differentiating these closely resembling fetal aortic arch abnormalities is important for proper prenatal counselling and immediate neonatal evaluation. In this pictorial essay, we describe these three cases and its typical imaging features using conventional and four-dimensional echocardiography.

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Article Synopsis
  • The study evaluates long-term outcomes for patients with tetralogy of Fallot, emphasizing the role of pulmonary annular hypoplasia and dysfunction over time.
  • The research analyzed data from 131 heart repairs performed from 2004 to 2014, classifying patients based on the severity of their pulmonary annular conditions.
  • Results showed a 100% survival rate, with varying rates of pulmonary valve replacement and right ventricular outflow tract reoperations among the different patient groups during the 9.6-year follow-up.
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Article Synopsis
  • Current methods to predict sudden cardiac death (SCD) in children with hypertrophic cardiomyopathy (HCM) are insufficient, although late gadolinium enhancement (LGE) in CMR imaging has shown a link to SCD in adults.
  • This study aimed to assess the significance of LGE in HCM patients under 21 years, utilizing data from various international centers between 2015 and 2022.
  • Results indicated that 32.9% of the 700 patients had LGE, and those with LGE were more likely to experience SCD or related events, emphasizing the potential role of LGE in clinical assessments for younger patients with HCM.
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Background: Patients with hypoplastic left heart syndrome undergo the comprehensive stage 2 procedure as the second stage in the hybrid approach toward Fontan circulation. The complexity of comprehensive stage 2 procedure is considered a potential limitation, and limited information is available on its anesthetic management. This study aims to address this gap.

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: The objective of our study was to assess the prenatal course, associated anomalies and postnatal outcome and the predictive value of various prenatal parameters for survival in prenatally diagnosed cases of truncus arteriosus communis (TAC). : We evaluated cases from four centers between 2008 and 2021. : In 37/47 cases (78.

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Ex vivo heart perfusion: an updated systematic review.

Heart Fail Rev

September 2024

Cardiac Surgery Unit, Cardio-thoraco-vascular and Public Health Department, Padova University Hospital, Padua, Italy.

Due to the discrepancy between patients awaiting a heart transplant and the availability of donor hearts, strategies to expand the donor pool and improve the transplant's success are crucial. This review aims to summarize current knowledge on the ex vivo heart preservation (EVHP) experience as an alternative to standard cold static storage (CSS). EVHP techniques can improve the preservation of the donor's heart before transplantation and allow for pre-transplant organ evaluation.

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Background: Coronary atherosclerosis detected by imaging is a marker of elevated cardiovascular risk. However, imaging involves large resources and exposure to radiation. The aim was, therefore, to test whether nonimaging data, specifically data that can be self-reported, could be used to identify individuals with moderate to severe coronary atherosclerosis.

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The great artery relationship in transposition of great arteries (TGA) is based on the degree of resorption and growth of subsemilunar conus. In transposition of great arteries, the spatial relationship of the great arteries can be variable. Commonly, the aorta will be related right and anterior to pulmonary artery (D-TGA).

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Image noise and vascular attenuation are important factors affecting image quality and diagnostic accuracy of coronary computed tomography angiography (CCTA). The aim of this study was to develop an algorithm that automatically performs noise and attenuation measurements in CCTA and to evaluate the ability of the algorithm to identify non-diagnostic examinations. The algorithm, "NoiseNet", was trained and tested on 244 CCTA studies from the Swedish CArdioPulmonary BioImage Study.

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Objectives: Myocardial recovery in children supported by a durable left ventricular assist device is a rare, but highly desirable outcome because it could potentially eliminate the need for a cardiac transplant and the lifelong need for immunosuppressant therapy and the risk of complications. However, experience with this specific outcome is extremely limited.

Methods: All patients < 19 years old supported by a durable left ventricular assist device from the European Registry for Patients with Mechanical Circulatory Support database were included.

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Background: The prognosis of children with heart failure varies considerably. After treatment, left ventricular ejection fraction (LVEF) can be improved in some children. The aim of this study was to analyze the clinical features of children with heart failure accompanied by cardiomyopathy and recovered ejection fraction [heart failure with recovered ejection fraction (HFrecEF)] and to identify the predictors of improved LVEF.

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Background: Long-term survival after single-ventricle palliation and the effect of dominant ventricle morphology in large, unselected series of patients are scarcely reported.

Methods And Results: This nationwide cohort study included all children undergoing operation with single-ventricle palliation during their first year of life in Sweden between January 1994 and December 2019. Data were obtained from institutional records and assessment of underlying cardiac anomaly and dominant ventricular morphology was based on complete review of medical records, surgical reports, and echocardiographic examinations.

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Histopathology of congestive nephropathy: a case description and literature review.

ESC Heart Fail

August 2024

Department of Internal Medicine II, University Hospital Giessen and Marburg, Justus-Liebig-University Giessen, Giessen, Germany.

Congestive nephropathy is an underappreciated manifestation of cardiorenal syndrome and is characterized by a potentially reversible kidney dysfunction caused by a reduced renal venous outflow secondary to right-sided heart failure or intra-abdominal hypertension. To date, the histological diagnostic criteria for congestive nephropathy have not been defined. We herein report a case of acute renal dysfunction following cardiac allograft failure and present a review of the relevant literature to elucidate the current understanding of the disease.

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Three-dimensional virtual dissection using high-definition live tissue rendering ultrasound tool of a 23-week gestation fetus with situs solitus, mirror image dextrocardia, ventricular septal defect, aortic override, and pulmonary atresia.

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Background: Isolated redundant foramen ovale flap aneurysm (RFOA) in the absence of restrictive foramen ovale is believed to be a cause for pseudocoarctation of aorta since the impediment of blood flow to the left heart can be severe, resembling the picture of left ventricular hypoplasia with retrograde aortic flow. The primary objective of the study is to find whether RFOA is always a benign lesion. The main focus of the study is to share my experience in particular on fetuses having redundant foramen ovale flap aneurysm developing into coarctation of aorta and to study the associated factors.

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A deep multi-stream model for robust prediction of left ventricular ejection fraction in 2D echocardiography.

Sci Rep

January 2024

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

We propose a deep multi-stream model for left ventricular ejection fraction (LVEF) prediction in 2D echocardiographic (2DE) examinations. We use four standard 2DE views as model input, which are automatically selected from the full 2DE examination. The LVEF prediction model processes eight streams of data (images + optical flow) and consists of convolutional neural networks terminated with transformer layers.

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Article Synopsis
  • This study investigates lead and generator malfunctions in pediatric patients with cardiac devices, revealing that 29% of patients experienced lead-related complications over an average follow-up of 6.4 years.
  • The majority of complications were discovered through device checks, but there was often a delay in recognizing the issues, with a median detection time of 1.3 months.
  • The findings highlight the need for vigilant monitoring of both symptomatic and asymptomatic patients to enhance safety, suggesting that improving the durability of epicardial electrodes is essential.
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Advances in fetal echocardiography including newer techniques like 4D spatio-temporal image correlation technology has improved our understanding of fetal cardiac and extracardiac abnormalities. High resolution ultrasound combined with color Doppler and 3D rendering have contributed to an improved understanding of the fetal vascular system and its anomalies. This pictorial essay including ultrasound images and videos alongside their respective clay models, provides precise information of duct anatomy in fetuses with pulmonary atresia and aortic arch abnormalities.

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Myocardial recovery in children supported with a durable ventricular assist device-a systematic review.

Eur J Cardiothorac Surg

August 2023

Children's Hospital Zurich, Pediatric Heart Centre, Department for Congenital Heart Surgery, Zurich, Switzerland.

Objectives: A small percentage of paediatric patients supported with a ventricular assist device (VAD) can have their device explanted following myocardial recovery. The goal of this systematic review is to summarize the current literature on the clinical course in these children after weaning.

Methods: A systematic literature search was performed on 27 May 2022 using Embase, Medline ALL, Web of Science Core Collection, Cochrane Central Register of Controlled Trials and Google Scholar to include all literature on paediatric patients supported by a durable VAD during the last decade.

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After bidirectional cavopulmonary connection (BDCPC) central pulmonary arteries (PAs) of single ventricle (SV) patients can be affected by stenosis or even closure. Aim of this study is to compare SV patients with and without PA-stent implantation post-BDCPC regarding risk factors for stent implantation and outcome. Single center, retrospective (2006-2021) study of 136 SV consecutive patients with and without PA-stent implantation post-BDCPC.

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Background In patients after heart transplantation, systemic arterial hypertension and enhanced central aortic stiffness contribute to increased ventricular afterload, which might lead to graft dysfunction. The aim of our study was to characterize systemic arterial elastance and its impact on left ventricular function and ventriculo-arterial coupling in a cohort of children, adolescents, and young adults after heart transplantation using invasive conductance catheter technique. Methods and Results Thirty patients who had heart transplants (age, 20.

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Article Synopsis
  • The study focuses on using a Contegra monocusp and native leaflet tissue to create a functioning pulmonary valve in children with severe tetralogy of Fallot, aiming to avoid the need for a transannular patch.
  • Eighteen patients were analyzed, with successful operations leading to good health post-surgery; most patients had a hospital stay averaging about 12.5 days, and complications included one death and several requiring catheter interventions.
  • Follow-up results showed significant improvements in pulmonary annulus sizes and a 79.25% freedom from dysfunction at 36 months, suggesting the method is effective and replicable for future procedures.
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Current status and challenges in prenatal and neonatal screening, diagnosis, and management of congenital heart disease in China.

Lancet Child Adolesc Health

July 2023

Maternal-Fetal Medicine Centre in Fetal Heart Disease, Beijing Anzhen Hospital, Capital Medical University, Beijing, China; Beijing Key Laboratory of Maternal-Fetal Medicine in Fetal Heart Disease, Beijing, China; Beijing Laboratory for Cardiovascular Precision Medicine, Beijing, China. Electronic address:

Congenital heart disease (CHD), a wide spectrum of diseases with varied outcomes, is the most common congenital malformation worldwide. In this Series of three papers, we describe the burden of CHD in China; the development of screening, diagnosis, treatment, and follow-up strategies; and challenges associated with the disease. We also propose solutions and recommendations for policies and actions to improve the outcomes of CHD.

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