Physiological and Biochemical Effects of Echium Amoenum Extract on Mn-Imposed Parkinson Like Disorder in Rats.

Manganism is a cognitive disorder take places in peoples are exposed to environmental manganese pollution. Overexposure to manganese ion (Mn) mainly influences central nervous system and causes symptoms that increase possibility of hippocampal damages. In this study rats were administrated by two different doses of MnCl2 and behavioral and physiological consequences were evaluated.

Improving effects of Echium amoenum aqueous extract on rat model of Alzheimer's disease.

Alzheimer's disease (AD) is a progressive neurodegenerative disorder greatly accompanied by oxidative stress and acetylcholine reduction in synaptic cleft that leads to dementia. Previously approved there is correlation between nucleus basalis of Meynert (NBM) degeneration and loss of memory, learning ability and thought. The aim of this study was to investigate improving effects of Echium amoenum aqueous extract on memory deficient, pathophysiological and oxidative damages imposed by NBM lesion in rats as documented AD model.

Antioxidant effects of alfalfa can improve iron oxide nanoparticle damage: Invivo and invitro studies.

Medicago sativa Linn. or alfalfa (Leguminosae) has been used traditionally as an effective cure for CNS, heart and metabolic disorders and digestive aids. Alfalfa is a resistant plant against stress due to small antioxidant molecules and enzymes.

In vitro toxicity of iron oxide nanoparticle: oxidative damages on Hep G2 cells.

During the past years many studies have been done highlighting the great need for a more thorough understanding of cell-iron oxide nanoparticle interactions. To improve our knowledge in this field, there is a great need for standardized protocols that would allow to comparing the cytotoxic potential of any Fe2O3-NP type with previously studied particles. Several approaches are reported that several parameters which are of great importance for Fe2O3 nanoparticle induced toxicity.