45 results match your criteria: "Paulista State University Julio de Mesquita Filho[Affiliation]"

Parasitic infections in non-human primates (NHPs) kept ex situ can be caused by zoonotic protists like and . In Brazil, little is known about these infections in neotropical species. This study aimed to identify Amoebozoa and Ciliophora groups in fecal samples through in vitro isolation and molecular analysis, mapping their distribution in Brazil.

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Escherichia coli is a zoonotic bacterium, and its resistance to antimicrobials has become an increasing problem in global health. This study aimed to determine the phenotypic and genotypic pooled prevalence of E. coli with antimicrobial resistance profiles in poultry through systematic review and meta-analysis.

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Article Synopsis
  • Visceral leishmaniasis (VL) diagnosis is critical, especially in untreated cases, with the gold standard being bone marrow aspirate, which is invasive and not always feasible, particularly when HIV is involved.
  • A study in Brazil examined 127 VL patients, with 37.8% also having HIV, comparing diagnostic tools like the rK39-ICT test, PCR, and IFAT against a reference standard of parasitological examination.
  • Results showed that while rK39-ICT was effective in HIV-negative patients, it significantly underperformed in HIV-positive patients compared to PCR, highlighting the need for improved diagnostic strategies that consider the presence of HIV.
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The main objective of the study was to assess the occurrence of non-aids-related comorbidities typical of aging in people living with HIV diagnosis 20 years ago or more and under treatment with antiretroviral drugs for a long time. The associations between the same age group in people living with HIV with reported ART use 20 + years and people living with HIV with reported ART use between two and five years in relation to the risk of comorbidities studied, there was a predominance of metabolic alterations in the 50-60 and 60 + age groups (p < 0.003).

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The present study aimed to verify the effect of acute nitrate supplementation on oxidative, phosphocreatine, and glycolytic energy contribution (C, C, and C respectively) during a high-intensity intermittent exercise (HIIE). Fifteen physically active subjects were submitted to incremental running test on a treadmill and two random HIIE (10 × 1 min at maximal aerobic speed with 1 min of passive recovery) in the following conditions: sodium nitrate (SN) or Placebo (PL). Repeated measure ANOVA was used to compare C, and C within the 10 efforts.

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  • A study investigated how a special diet (Sannimix) for female quails affects their eggs and chicks, focusing on factors like maternal diet, egg incubation temperature, and embryonic development.
  • Quail hens on the Sannimix diet outperformed those on a regular diet, producing higher-quality embryos with better growth rates for their chicks at both 0 and 15 days old.
  • The findings suggest that the Sannimix diet leads to improved health and development in offspring, even under higher incubation temperatures, by enhancing oxidative stability and gene expression related to growth.
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To evaluate the microstructural characterization, mechanical properties and antimicrobial activity of acrylic resins incorporated with different concentrations of reduced graphene oxide (rGO). Specimens were made of self-cured and heat-cured acrylic resins for the control group and concentrations of 0.5%, 1%, and 3%.

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This study aimed to incorporate β-AgVO and rGO into self-curing (SC) and heat-curing (HC) acrylic resins and to evaluate their physicochemical, mechanical, and antimicrobial properties while correlating them with the characterized material structure. Acrylic resin samples were prepared at 0 % (control), 0.5 %, 1 %, and 3 % for both nanoparticles.

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The resistance of pest insects to biopesticides based on the bacterium Bacillus thuringiensis (Bt) is normally associated with changes to the receptors involved in the mechanism of action of the pesticidal proteins produced by Bt. In some strains of Plutella xylostella (the diamondback moth) resistance has evolved through a signalling mechanism in which the genes encoding the receptor proteins are downregulated whereas in others it has been linked to structural changes in the receptors themselves. One such well characterized mutation is in the ABCC2 gene indicating that changes to this protein can result in resistance.

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Chagas disease (CD) is a typical tropical illness caused by . The objective of this study was to assess the prevalence of Chagas disease in communities in two states of the Brazilian Amazon. Data collection occurred in July in the Alto Juruá region of Acre and in December in the communities of Humaitá, Amazonas, in 2019.

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Characteristics of Skeletal Muscle Strength in Subjects With Interstitial Lung Disease.

Arch Phys Med Rehabil

June 2024

Department of Physiotherapy, Laboratory of Research in respiratory physiotherapy (LFIP), Londrina State University, Londrina, Brazil; Department of Rehabilitation Sciences, University Pitágoras UNOPAR, Londrina, Brazil. Electronic address:

Objectives: To investigate muscle strength and the prevalence of muscle weakness in adults with interstitial lung diseases (ILDs) compared to healthy subjects.

Design: Cross-sectional (description of clinical features).

Setting: Public referral center (University Hospital).

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Urban activities pollute aquatic ecosystems, and the integrity of organisms such as fish. The use of cytological techniques, such as the analysis of blood cellular integrity using the Micronucleus test, can help detect mutagenic damage as a result to urban effluents exposure. In this context, this study aimed to evaluate the frequency of micronucleus and other nuclear abnormalities in Oreochromis niloticus fish environmentally exposed to urban effluents in relation to their erythrocyte recovery capacity when exposed to clean water (30 and 45 days).

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Since previous literatureregarding the application of the metaverse in educationis scarce, the present letter aimed to highlight possible applications, as a complementary tool for the classroom, in the oral and maxillofacial radiology academic experience.Thepotential risksof the metaverse are also discussed. The metaverse and its possible applications, especially related to enhanced teaching and learning, will become a hot topic in the near future, and therefore, there will be a challenging learning curve before the educator makes the most of these innovative educational tools empowered by deeply interactive virtual reality technology.

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Copper(II) complexes have become a potential alternative to the use of platinum drugs in cancer therapy due to their multi-target mode of action. In this context, we report the syntheses of new mononuclear and dinuclear coordination compounds of this element, 1 and 2, derived from the ligand 5-methylsalicylaldehyde 2-furoyl hydrazone (H2L). All three compounds were structurally and spectroscopically characterized, both in the solid state and in solution.

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ChatGPT: a tool for scientific writing or a threat to integrity?

Br J Radiol

December 2023

Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.

The use of ChatGPT as a tool for writing and knowledge integration raises concerns about the potential for its use to replace critical thinking and academic writing skills. While ChatGPT can assist in generating text and suggesting appropriate language, it should not replace the human responsibility for creating innovative knowledge through experiential learning. The accuracy and quality of information provided by ChatGPT also require caution, as previous studies have reported inaccuracies in references used by chatbots.

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Cardioprotective Effects of the 4-Week Aerobic Running Exercises Before Treatment with Doxorubicin in Rats.

Cardiovasc Toxicol

August 2023

Graduate Program in Health Sciences-PPGCS, Faculty of Medicine, Universidade Federal de Uberlândia-UFU, Uberlândia, MG, Brazil.

Doxorubicin is associated with cardiotoxicity, and physical exercise seeks to minimize the toxic effects of doxorubicin through physiological cardiac remodeling, as well as the reduction of oxidative stress, evidenced by previous studies. This study aimed to analyze whether running training before treatment with doxorubicin influences tolerance to physical exertion and cardiotoxicity. Thirty-nine male Wistar rats, aged 90 days and weighing between 250 and 300 g, were divided into 4 groups: Control (C), Doxorubicin (D), Trained (T), and Trained + Doxorubicin (TD).

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Background: The palliative care provided to cancer patients should also contemplate the psychological and spiritual dimensions of care.

Aims: This study aimed to compare religiosity and spiritual/religious coping (SRC) of cancer patients in palliative care with a group of healthy volunteers and determine whether sociodemographic characteristics affected this association.

Methods: This was a case-control study conducted with 86 patients living with cancer from an outpatient palliative care clinic of the São Paulo State University (UNESP) medical school, Botucatu, Brazil and 86 healthy volunteers.

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Article Synopsis
  • Mastitis, a significant disease in dairy cattle primarily caused by Staphylococcus bacteria, leads to economic losses due to diminished milk production and quality.
  • The study aimed to assess whether homeopathy can effectively manage pathogenic Staphylococcus spp. in dairy cows by investigating biofilm production and the presence of related genes.
  • Findings showed that while S. aureus prevalence was similar in treated and untreated cows, a notable portion of coagulase-negative isolates came from homeopathy-treated cows, with certain genes linked to biofilm production being more common in this group.
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Q fever and brucellosis are zoonoses that cause fever and other systemic clinical signs in humans; their occurrences are neglected and the differential diagnosis for some diseases is disregarded. This study aimed to investigate the seropositivity for Coxiella burnetii and Brucella spp. antibodies in patients suspected of dengue from 38 municipalities in the state of São Paulo, Brazil.

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In this study, a lichen-like structure was obtained through the production of a unique biomass, formed by algae cells of adhering to the mycelium of filamentous fungal This structure was composed in two steps; in the first one, microalgal cells and spores were incubated separately, and in the second one, after 72 h of growth, isolated, mature mycelium was harvested and added to cell culture. For spores' incubation, a culture medium containing only 2 g·L of glucose and minerals was used. This culture medium, with low sugar content, provided a fungal biomass to the anchorage of microalgae cells.

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The objective was to evaluate the accuracy of B-mode ultrasonography and ARFI elastography in detecting malignancy in canine splenic lesions. Thirty-seven spleens with abnormalities (16 benign and 21 malignant) from dogs of different breeds and ages were evaluated. Echogenicity, echotexture, organ length and height were evaluated using B-mode.

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Neonatal Transfusion Practice: Hemolysis Markers After In Vitro Infusion of Packed Red Blood Cells by the Gravitational Method or Syringe Pump in a Peripheral Catheter.

J Perinat Neonatal Nurs

November 2021

Nursing School, Federal University of São Paulo, São Paulo, Brazil (Drs Orsi and Avelar and Mss Kita and de Souza); and Department of Biostatistics, Paulista State University Julio de Mesquita Filho, Botucatu, São Paulo, Brazil (Dr Tsunemi).

The objective of this study was to verify the influence of the gravitational infusion method or syringe infusion pump on changes in hemolysis markers of irradiated and nonirradiated packed red blood cells (PRBCs) in vitro administered in a neonate peripheral intravenous catheter. An experimental study was conducted in a laboratory under controlled environmental conditions. Irradiated and nonirradiated PRBCs were administered in triplicate by the gravitational method and 10-mL/hour syringe infusion pump, in peripheral intravenous catheter, Vialon, 24-G caliber.

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Micronucleus and different nuclear abnormalities in wild birds in the Cerrado, Brazil.

Environ Sci Pollut Res Int

February 2022

Laboratory of Ecotoxicology and Animal Systematics, Institute Federal Goiano, IF Goiano, Campus Rio Verde, Rodovia Sul Goiana, Km 01, Zona Rural, Rio Verde, Goiás, CEP 75.901-970, Brazil.

Free-living birds play an important role as bioindicators in natural environments. In this study, we used the micronucleus test and nuclear erythrocyte abnormalities to investigate the difference in the genotoxic damage frequency between animals in agricultural areas (soybean planting) in relation to the conserved area. It was also discussed the bird's eating habits, which are important for ecotoxicological analysis.

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Bioinsecticides based on Bacillus thuringiensis (Bt) Berliner, 1915 are widely used to control lepidopteran in several crops. However, surviving insects exposed to the sub-lethal concentration of Bt-based bioinsecticides can suffer a multitude of effects on the biological conditioning known as hormesis. Here, we aimed to provide a clearer understanding of the biological conditioning of Anticarsia gemmatalis (Hübner, 1818), exposed to different concentrations of a Bt-based bioinsecticide, by assessing life table parameters over three generations.

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Article Synopsis
  • Anurans, like grassfrogs, are facing global population declines due to habitat destruction and contamination, which affects their health.
  • Morphological indicators, including micronuclei and other nuclear abnormalities, can help assess the impacts of these environmental changes.
  • The study found that grassfrogs from soybean plantations exhibited significantly higher frequencies of these abnormalities compared to those from protected areas, indicating detrimental effects of agricultural practices on their cellular health.
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