9,496 results match your criteria: "Paul's Hospital[Affiliation]"
Increased severity of multidrug-resistant Shigella sonnei infections in people experiencing homelessness.
Clin Infect Dis
November 2024
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Background: Shigella sonnei has caused sexually transmitted enteric infections in men who have sex with men (MSM) in Vancouver. We recently observed a high rate of multidrug-resistant (MDR) S. sonnei bacteremia among persons experiencing homelessness (PEH).
View Article and Find Full Text PDFThe BNT162b2 mRNA vaccine demonstrates reduced age-associated T1 support and .
iScience
November 2024
Precision Vaccines Program, Department of Pediatrics, Boston Children's Hospital, Boston, MA 02115, USA.
mRNA vaccines demonstrate impaired immunogenicity and durability in vulnerable older populations. We hypothesized that human modeling and proteomics could elucidate age-specific mRNA vaccine actions. BNT162b2-stimulation changed the plasma proteome of blood samples from young (18-50Y) and older adult (≥60Y) participants, assessed by mass spectrometry, proximity extension assay, and multiplex.
View Article and Find Full Text PDFChallenges in institutional ethical review process and approval for international multicenter clinical studies in lower and middle-income countries: the case of PARITY study.
Front Pediatr
November 2024
Division of Pediatric Critical Care Medicine, Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, OH, United States.
Background: One of the greatest challenges to conducting multicenter research studies in low and middle-income countries (LMICs) is the heterogeneity in regulatory processes across sites. Previous studies have reported variations in requirements with a lack of standardization in the Institutional Review Board (IRB) processes between centers, imposing barriers for approval, participation, and development of multicenter research.
Objectives: To describe the regulatory process, variability and challenges faced by pediatric researchers in LMICs during the IRB process of an international multicenter observational point prevalence study (Global PARITY).
Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections.
N Engl J Med
November 2024
From the Division of Infectious Diseases, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto (N.D.), Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, University of Toronto, Toronto (A.R.), the Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto (R. Pinto); the Department of Infectious Diseases, Monash University, Clayton, Melbourne, VIC, Australia (B.A.R.), the Department of Intensive Care, Monash Medical Centre, Melbourne, VIC, Australia (Y.S.); the Cardiothoracic and Vascular Intensive Care Unit, Auckland City Hospital, Auckland, New Zealand (R. Parke); the Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada (D.C.); the Intensive Care Department, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia (Y.A.); the Department of Critical Care Medicine, Queen's University, Kingston, ON, Canada (J. Muscedere), the Department of Critical Care Medicine, Royal Columbian Hospital, Vancouver, BC, Canada (S. Reynolds), Critical Care Medicine, Capital District Health Authority, Dalhousie University, Halifax, NS, Canada (R.H.); Monash Medical Centre, Clayton, VIC, Australia (D.B.D.); Critical Care Medicine, Auckland City Hospital, New Zealand (C. McArthur), the Cardiothoracic and Vascular Intensive Care Unit, Auckland City Hospital, Auckland, New Zealand. (S. McGuinness); the Infectious Diseases Unit, Sheba Medical Center, Ramat-Gan, and Faculty of medicine, Ramat-Aviv, Tel-Aviv, Israel (D.Y.); Infectious Diseases, University Health Network, University of Toronto, Toronto (B.C.); Critical Care Medicine, North York General Hospital, Toronto (A.G., P.S.), Infectious Diseases, North York General Hospital, Toronto (P. Das), Critical Care Medicine, Mount Sinai Hospital, Unity Health Toronto, Toronto (M. Detsky), the Department of Medicine, University of Toronto, Toronto (A.M.); Sinai Health, Division of General Internal Medicine, Toronto, Toronto (M.F.), Infectious Diseases, Michael Garron Hospital, University of Toronto, Toronto (J.E.P.), Infectious Diseases, Michael Garron Hospital, Toronto (C. Kandel), Critical Care Medicine and Infectious Diseases, University of Alberta, Edmonton, Canada (W.S.), Department of Critical Care Medicine, University of Alberta and Alberta Health Services, Edmonton, Canada (S.M.B.), the Department of Medicine, Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada (N.S.), the Department of Anaesthesia, Hamilton General Hospital, McMaster University, Hamilton, ON, Canada (E.B.-C.), the Faculty of Health Sciences, Hamilton General Hospital, McMaster University, Hamilton, ON, Canada (R.W.), the Departments of Surgery and Critical Care, McGill University Health Center, Montreal (K.K.); the Departments of Infectious Diseases and Pathology, Middlemore hospital, University of Auckland, New Zealand (S. Morpeth), Organ Donation New Zealand, New Zealand Blood Service, Auckland, New Zealand (A. Kazemi), Intensive Care Medicine, Middlemore Hospital, Auckland, New Zealand (A.W.); the Division of Infectious Diseases, Ottawa Hospital, Ottawa Hospital Research Institute, Ottawa (D.R.M.), the Department of Medicine, Ottawa Hospital, University of Ottawa, Ottawa (L.M.), Niagara Health Knowledge Institute, Niagara Health, St. Catharines, ON, Canada (J.T.), the Department of Medicine, Université de Sherbrooke, QC, Canada (F. Lamontagne); the Department of Microbiology and Infectious Diseases, Université de Sherbrooke, QC, Canada (A.C.), Surgery and Critical Care Medicine, Unity Health Toronto, University of Toronto, Toronto (J. Marshall); Critical Care and Medicine, Unity Health Toronto-St. Michael's Hospital, University of Toronto, Toronto (J.O.F.), Critical Care Medicine, Unity Health Toronto, Toronto (R.C.), the Department of Medicine, Unity Health Toronto, Toronto (M. Downing), the Department of Medicine, Infectious Diseases, Trillium Health Partners, University of Toronto, Toronto (C.G.); the School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia (J.D.); the Division of Critical Care, Department of Medicine, McMaster University, Hamilton, ON, Canada (E.D.), St. Joseph's Healthcare Hamilton, McMaster University, Hamilton, ON, Canada (J.N.), the Department of Medicine (Infectious Diseases), Queen's University, Kingston, ON, Canada (G.E.); the Department of Medicine, King Faisal Specialist Hospital and Research Center, Al Faisal University, Jeddah, Saudi Arabia (B.A.), the Department of Pathology and Laboratory Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia (S.A.); the Department of Medicine, University of Western Ontario, London, Canada (C. Martin); the Department of Medicine, London Health Sciences Centre, London, ON, Canada (S.E.), the Department of Medicine, Western University, London, ON, Canada (I.B.), the Department of Medicine, Université Laval, Quebec, QC, Canada (F. Lauzier), the Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Université Laval, Quebec, QC, Canada (A.T.), the Population Health and Optimal Health Practice Research Unit, Centre Hospitalier Universitaire de Québec-Université Laval Research Center, Québec, QC, Canada (A.T.), the Department of Critical Care, University of Calgary Cumming School of Medicine, Calgary, AB, Canada (H.T.S.), the Department of Medicine, University of Calgary and Alberta Health Services (Calgary), Calgary, AB, Canada (J.C.), the Division of General Internal Medicine, Department of Medicine, McGill University Health Centre, Montreal (E.G.M.), the Division of Infectious Diseases, Department of Medicine, McGill University, Montreal (T.C.L.); the Department Infectious Diseases, St. George Hospital, UNSW Medicine and Health, Sydney (R.S.); the Divisions of Infectious Diseases and Medical Microbiology, University of British Columbia, Vancouver, Canada (J.G.); the Intensive Care Unit, Rabin Medical Centers, Tel Aviv University, Tel Aviv, Israel (I.K.); the Intensive Care Research Programme, Medical Research Institute of New Zealand, Wellington, New Zealand (P.Y.), Medical Research Institute of New Zealand, Wellington, New Zealand. (C.L.); the Department of Infectious Diseases, Redcliffe Hospital, Redcliffe, QLD, Australia (K.O.), Infectious Diseases, Redcliffe Hospital, University of Queensland, Redcliffe, Australia (M.E.), Infectious Diseases, Sunshine Coast University Hospital, Sunshine Coast University Hospital, Birtinya, QLD, Australia (K.C.); Medicine, Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montreal (P.A.); the Department of Anaesthesia, Rotorua Hospital, Rotorua, New Zealand (U.B.); Infectious Diseases, William Osler Health System, Brampton, ON, Canada (T. Havey), Critical Care Medicine, William Osler Health System, Brampton, ON, Canada (A.B.); the Department of Intensive Care Medicine, Bern University Hospital, University of Bern, Bern, Switzerland (J.P.); Brantford General Hospital, McMaster University, Brantford, ON, Canada (B.R.); the Intensive Care Unit, Fiona Stanley Hospital, University of Western Australia, Murdoch, WA, Australia (E.L.); the Department of Medicine, University of Manitoba, Winnipeg, Canada (S.L.), the Division of Critical Care Medicine and Infectious Diseases, Health Sciences Centre, University of Manitoba, Winnipeg, Canada (A. Kumar), the Department of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada (R.Z.); the Infectious Diseases Unit, Sheba Medical Center, Ramat Gan, Israel (T. Hoffman); the Infectious Diseases Unit, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia. (D.P.); Infectious Diseases, Memorial University, St. John's, NL, Canada (P. Daley); General and Subspecialty Medicine, Grampians Health Ballarat, Ballarat, VIC, Australia (R.J.C.); Service des soins intensifs, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal (E.C.), Critical Care Medicine, CIUSSS MCQ CHAUR, University of Montreal, Montreal (J.-F.N.); Clinical Microbiology and Infection Prevention and Control, Auckland Hospital, Auckland, New Zealand (S. Roberts); the Department of Intensive Care Medicine, Frankston Hospital, Frankston, VIC, Australia (R.T.), the Department of Intensive Care Medicine, Monash University, Melbourne, VIC, Australia (S.G.); the Department of Critical Care, Island Health Authority, Royal Jubilee Hospital, British Columbia, Victoria, Canada (G.W.); Infectious Diseases, Wollongong Hospital, Wollongong, NSW, Australia (O.S.), Infectious Diseases, Wollongong Hospital, University of Wollongong, Wollongong, NSW, Australia (S. Miyakis); the Department of Medicine, St. Paul's Hospital, University of British Columbia, Vancouver, Canada (P. Dodek), Infectious Diseases, Richmond Hospital, Richmond, BC, Canada (C. Kwok), and the Interdepartmental Division of Critical Care Medicine, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto (R.A.F.).
Background: Bloodstream infections are associated with substantial morbidity and mortality. Early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain.
Methods: In a multicenter, noninferiority trial, we randomly assigned hospitalized patients (including patients in the intensive care unit [ICU]) who had bloodstream infection to receive antibiotic treatment for 7 days or 14 days.
Advancing gender equity to improve kidney care for women: a patient perspective.
Nat Rev Nephrol
January 2025
Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Squats, spinach, and soul: considering disparities in prehabilitation medicine before programmatic implementation.
Can J Anaesth
December 2024
Department of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Interstitial Lung Abnormalities on Unselected Abdominal and Thoracoabdominal CT Scans in 21 118 Patients.
Radiology
November 2024
From the Scienze Radiologiche, Department of Medicine and Surgery, University of Parma, Parma, Italy (N.S., G.M., V.R.P., S.E.G., E.B., F.S., C.M., F.M., R.E.L., M.S.); Department of Medicine, University of British Columbia and Center for Heart Lung Innovation, St Paul's Hospital, Vancouver, Canada (C.J.R.); Department of Radiology, Brigham and Women's Hospital, Boston, Mass (H.H.); National Heart and Lung Institute, Imperial College London, London, England (S.L.F.W.); and University Hospital of Parma, Parma, Italy (E.I.).
Article Synopsis
- Interstitial lung abnormalities (ILAs) are incidental findings on CT scans that may indicate early stages of interstitial lung disease, but data on their prevalence in routine clinical practice is limited.
- A study reviewed CT scans from patients aged 50 and older at a tertiary hospital and found that ILAs were present in 1.7% of scanned patients, with a significant number being underreported in original clinical reports.
- The presence of fibrotic ILAs significantly increased the risk of respiratory-related mortality, highlighting the importance of recognizing and reporting these abnormalities in clinical settings.
Redo-TAVI with the SAPIEN 3 valve in degenerated calcified CoreValve/Evolut explants.
EuroIntervention
November 2024
Cardiovascular Translational Lab, Centre for Heart Lung Innovation, University of British Columbia and Providence Health Care, St. Paul's Hospital, Vancouver, Canada.
Article Synopsis
- Redo-transcatheter aortic valve implantation (TAVI) is often needed for failed aortic valves, specifically examining SAPIEN 3 (S3) valves in degenerated CoreValve/Evolut (CV/EV) valves, which is not fully understood.
- The study assessed the performance of S3 valves following implantation in calcified CV/EV valves through various hydrodynamic tests, measuring factors like mean gradient, effective orifice area, and leaflet behaviors.
- Results indicated that S3 valves generally performed well, showing decreased mean gradient and acceptable effective orifice area, but issues like underexpansion, leaflet pinwheeling, and calcium protrusion were noted, highlighting the need for further research on long
Low-flow, low-gradient aortic stenosis: an understanding is still a long way off.
EuroIntervention
November 2024
St Paul's Hospital, Vancouver, BC, Canada.
Preferences and Feasibility of Long-Acting Technologies for the Treatment of Hepatitis C Virus: A Survey of Patients in Diverse Low- and Middle-Income Countries.
J Viral Hepat
November 2024
Section of Infectious Diseases, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Despite available curative treatments, global rates of hepatitis C virus (HCV) infection persist with significant burden in low- and middle-income countries (LMICs). Long-acting (LA) antiviral products are in development. This study explored the challenges and opportunities in LA-HCV treatment across three LMICs: Egypt, Ethiopia and India.
View Article and Find Full Text PDFQuality indicators for improved cardiovascular care: learnings from the National Institute for Health and Care Excellence.
Eur Heart J Qual Care Clin Outcomes
November 2024
Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Diagnostic Performance of AI-enabled Plaque Quantification from Coronary CT Angiography Compared with Intravascular Ultrasound.
Radiol Cardiothorac Imaging
December 2024
From the Department of Cardiology, Fiona Stanley Hospital, Perth, Australia (A.R.I.); Harry Perkins Institute of Medical Research, Curtin Medical School, Curtin University, 11 Robin Warren Dr, Murdoch, WA 6150, Australia (A.R.I.); Department of Radiology, St Paul's Hospital, University of British Columbia, Vancouver, Canada (G.T.); HeartFlow Inc, Mountain View, Calif (K.P., N.N., S.M.); Cardiovascular Research Foundation, Columbia University, New York, NY (A.M.); and Department of Cardiovascular Medicine, William Beaumont University Hospital-Corewell Health East, Royal Oak, Mich (R.D.S.).
Purpose To assess the diagnostic performance of a coronary CT angiography (CCTA) artificial intelligence (AI)-enabled tool (AI-QCPA; HeartFlow) to quantify plaque volume, as compared with intravascular US (IVUS). Materials and Methods A retrospective subanalysis of a single-center prospective registry study was conducted in participants with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention of the culprit vessel. Participants with greater than 50% stenosis in nonculprit vessels underwent CCTA, invasive coronary angiography, and IVUS of nonculprit lesion(s) between 2 and 40 days after primary percutaneous coronary intervention.
View Article and Find Full Text PDFTwo cases of postpartum vaginal stenosis: a case report.
J Med Case Rep
November 2024
Department of Obstetrics and Gynecology, St. Paul's Hospital Millennium Medical College, Swaziland Street, 1271, Addis Ababa, Ethiopia.
Background: Although vaginal stenosis following pelvic or vaginal radiotherapy for cancer treatment is a common complication, postpartum vaginal stenosis is a very rare obstetric complication. We report two cases of postpartum vaginal stenosis.
Case Presentation: The first was case was a 30-year-old para-I Ethiopian woman who presented with a history of foul-smelling vaginal discharge on her 11th postpartum day.
The psychometric properties of the amharic version of EuroQoL five-dimensions-five level among Ethiopian cervical cancer patients.
Health Qual Life Outcomes
November 2024
School of Pharmacy, Addis Ababa University, Addis Ababa, Ethiopia.
Article Synopsis
- The study evaluated the psychometric properties of the Amharic version of the EuroQoL Five-dimensions five level (EQ-5D) specifically for cervical cancer patients in Ethiopia, as little research has previously been done in this area.
- It involved a longitudinal survey with 371 participants who completed the EQ-5D and EORTC QLQ-C30 at the start and after three months of treatment, revealing improvements in health scores and strong correlations with other health-related quality measures.
- The findings indicate that the EQ-5D is effective in measuring health-related quality of life in this patient population, demonstrating both responsiveness and valid clinical difference measures.
Pediatric trichinosis: A case report.
Int J Surg Case Rep
December 2024
Addis Ababa University, College of Health Sciences, Ethiopia. Electronic address:
Background: Trichinellosis is a zoonosis, caused by roundworms of the genus Trichinella. Domestic pigs, wild boars, bears, rodents and horses are reservoir animals. We report a case of neck trichinosis presenting as lateral neck swelling.
View Article and Find Full Text PDFImpact of pH-dependent dynamics of human serum proteins on dialysis membranes: Cryptographic structure assessment, synchrotron imaging of membrane-protein adsorption, and molecular docking studies.
Colloids Surf B Biointerfaces
February 2025
Division of Biomedical Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, Saskatchewan S7N 5A9, Canada; Department of Chemical and Biological Engineering, University of Saskatchewan, 57 Campus Drive, Saskatoon, Saskatchewan S7N 5A9, Canada. Electronic address:
Proteins are fundamental to biochemical processes and critical in hemodialysis. This study investigates the impact of pH on human serum albumin (HSA), fibrinogen (FB), and transferrin (TRF) interactions with polyarylethersulfone (PAES) hemodialysis membranes. A multi-method approach was utilized, including protein crystallography for structural insights, hydration layer analysis to explore solvation and interaction potentials, molecular docking using AutoDock 4.
View Article and Find Full Text PDFLong-term Monitoring to Detect Risk of Sudden Cardiac Death in Inherited Arrhythmia Patients.
CJC Open
September 2024
Department of Cardiac Electrophysiology, St. Paul's Hospital, Vancouver, Ontario, Canada.
Article Synopsis
- The study focused on using long-term implantable loop recorders (ILRs) to assess arrhythmia risk in patients with inherited arrhythmia syndromes who do not have a strong indication for implantable cardioverter defibrillator (ICD) implantation.
- Researchers conducted a multicenter study from 2015 to 2020, enrolling 45 individuals, primarily with long-QT syndrome and Brugada syndrome, to monitor for arrhythmias and complications over time.
- Results indicated that ILRs successfully identified significant arrhythmic events in 42% of patients, leading to ICD implantation in 11% of cases, and highlighted their potential to improve risk stratification without any occurrences of sudden cardiac death during the study
An Optimized Assessment Pathway for Remote Patients: The Vancouver Facilitated Transcatheter Aortic Valve Implantation Program.
CJC Open
October 2024
Centre for Cardiovascular Innovation, St Paul's Hospital and Vancouver General Hospital, Vancouver, British Columbia, Canada.
Background: Novel pathways are needed to accommodate the increasing demand for transcatheter aortic valve implantation (TAVI) and ensure equitable access. A single Vancouver Facilitated TAVI program (VFTP) based at St. Paul's and Vancouver General Hospitals was established to streamline the assessment of remote patients with severe aortic stenosis using virtual technologies.
View Article and Find Full Text PDFRedo Mitral and Tricuspid Valve Surgery for Hemolytic Anemia, Following Hematuria and Anemia.
JACC Case Rep
October 2024
Department of Pathology, St. Paul's Hospital Millenium Medical College, College of Health Sciences, Addis Ababa, Ethiopia.
This study reports the challenges of rheumatic mitral and tricuspid valve re-repair on a child presenting with gross hematuria, hemolysis, and volume overload. Severe postoperative mitral and tricuspid valve regurgitation was the cause, and redo surgery for both valves resolved the acute issues.
View Article and Find Full Text PDFPrevalence of unused medications and determinants among the general public in Addis Ababa, Ethiopia.
BMC Public Health
November 2024
School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Background: Accumulation, improper storage, and disposal of unused medications in the households have become a growing public health, environmental and economic concern. However, the magnitude, reasons, and disposal practices of the problems are not well studied in Addis Ababa, the capital city of Ethiopia. Therefore, this study aims to assess the prevalence and determinants of unused medications at household levels in Addis Ababa, Ethiopia.
View Article and Find Full Text PDFCase report: - A case report on adult-onset cystic hygroma and literature review.
Int J Surg Case Rep
December 2024
Department of Otolaryngology-Head and Neck Surgery, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Introduction: Cystic hygromas are benign lesions arising due to an abnormality of lymphoid development and rarely present in adults.
Case Presentation: We present a case of a 25-year-old girl who presented with a complaint of left lateral neck swelling of 06 years duration which was painless and increased in size progressively associated with this she had some difficulty turning her neck to the left side of a year duration. On physical examination, it was noticed that she had a 15 ∗ 12 cm soft, non-tender mass over the left lateral neck from the sub-mandibular area to the supraclavicular area, anterior and posterior to the sternocleidomastoid muscle.
The Making of Confident Surgeons: Why and How?
Int Urogynecol J
November 2024
Centre for Advancing Health Outcomes, Vancouver, BC, Canada.
Low self-confidence in surgical residents can be associated with poor self-efficacy and perceptions of sub-optimal preparedness for practice at graduation. The influence of social and biologic determinants of confidence deserves further study. Through a randomized controlled trial of procedure-specific didactic and low fidelity simulation training for vaginal surgery, we showed positive correlations between self-confidence and objective performance in the real operating room for three different surgical procedures and through validated scales.
View Article and Find Full Text PDFInjury epidemiology and emergency department length of stay in trauma hospital in Addis Ababa, Ethiopia.
PLoS One
November 2024
Department of Preventive Medicine, School of Public Health, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Background: Injuries are a major cause of health problems in low- and middle-income countries than in high-income nations. This study aimed to describe injuries and identify factors associated with the emergency department (ED) length of stay (LoS).
Methods: This study was conducted at the Addis Ababa Burn, Emergency, and Trauma (AaBET) hospital in Addis Ababa, Ethiopia.
Simplifying acquisition of essential diagnostics: A comprehensive costing tool for anatomic pathology.
Am J Clin Pathol
November 2024
Center for Global Health, American Society for Clinical Pathology, Chicago, IL, US.
Objectives: Histopathology is the core diagnostic tool for cancer in pathology laboratories around the world, but there are disparities in access to diagnostics globally. As recognition of the need for cancer care and treatment grows, especially in the wake of World Health Organization programs for cervical, breast, and pediatric cancers, policymakers and health care funders are seeking tools and processes that allow for the largest number of patients to receive a diagnosis at the lowest cost.
Methods: As histopathology represents the most cost-effective diagnostic method by sheer number of tumor types and volume, understanding the detailed logistics and costs for histology as well as the impactful benefits of economies of scale (ie, larger volumes are less expensive per patient) and scope (ie, the multiple stains available after basic histology sectioning) is paramount to planning an effective publicly funded or government laboratory.
Short Survey on Cardiopulmonary Resuscitation and Automated External Defibrillator Training in Rural British Columbia Schools: Preliminary Findings and Hypothesis-Generating Insights.
CJC Open
October 2024
Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Background: British Columbia (BC) faces more than 7000 out-of-hospital cardiac arrests annually, which disproportionately affect rural areas, owing to their slower emergency medical service response and limited specialized care. Despite the known benefits of automated external defibrillator (AED) access and cardiopulmonary resuscitation (CPR) training, their status in rural BC schools is poorly documented.
Methods: We used an online survey of principals and vice-principals of rural schools in BC.