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Maternal High Fat Diet and its Expressions in the Heart and Liver in the Mice Embryogenesis.
Curr Mol Med
July 2024
Department of Clinical Medicine, Patan Hospital Affiliated to the Patan Academy of Health Sciences, Kathmandu, 44600, Nepal.
Background: The developmental biology for the nonalcoholic fatty liver disease and coronary heart disease are known but elaborative ideas of triglycerides phenomenon in the embryo-genesis of the liver and the heart are still not clear.
Objective: The aim of the study was to relate different triglycerides like LXRα, LPL, LDL R, PPARG-, SREBP-1C expression in the high fat fed mice with the normal fed diet mice in the process of developmental and embryo-genesis biology.
Methods: Tissue preparation was done by ripalysis.