672 results match your criteria: "Parnassia Psychiatric Institute[Affiliation]"

The Buss-Durkee Hostility Inventory (BDHI) is an important assessment scale of hostility in forensic psychiatry. We analyzed the validity and reliability of a Papiamento translation of the BDHI in 134 pre-trial defendants in Curaçao using Exploratory Structural Equation Modeling (ESEM). The reliability of the Direct and Indirect Hostility BHDI-P subscales were good and the reliability of the Social Desirability poor.

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Influence of cannabis use on incidence of psychosis in people at clinical high risk.

Psychiatry Clin Neurosci

September 2023

Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

Article Synopsis
  • The study aimed to explore the link between cannabis use and the development of psychotic disorders in individuals at high risk for psychosis, addressing both the incidence of psychosis and the ongoing presence of symptoms over time.
  • Researchers evaluated 334 at-risk individuals and 67 healthy controls over two years, assessing their cannabis use and mental health status through structured questionnaires and assessments.
  • Results indicated that a significant portion of participants developed psychosis, yet cannabis use did not show a meaningful connection to the onset, persistence of symptoms, or functional outcomes, challenging previous findings that suggested cannabis increases psychosis risk.
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Background: There is growing evidence that the COVID-19 pandemic, and its associated social distancing measures, affect adolescents' mental health. We wanted to examine whether and how the number and characteristics of adolescents' psychiatric emergency presentations have changed throughout the pandemic.

Methods: We extracted data from the records of 977 psychiatric emergency consultations of adolescents aged 12- 19 who had been referred to the mobile psychiatric emergency services in Rotterdam, the Netherlands between January 1 2018 and January1 2022.

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WHAT IS KNOWN ON THE SUBJECT?: The clinical effect of electroconvulsive therapy (ECT) has been confirmed for a majority of patients with several psychiatric disorders. ECT is mostly used in patients with severe depression. Choosing, persevering with and completing ECT depends on the patients' motivation for undergoing this therapy.

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Adult Attachment and Personal Recovery in Clients With a Psychotic Disorder.

Schizophr Bull Open

January 2023

Department of Psychiatry, ESPRI, Erasmus MC, Rotterdam, The Netherlands.

Background: Personal recovery has become a key objective in the treatment of clients with a psychotic disorder. So far it has been established that the two attachment dimensions, ie, anxious and avoidant, are negatively associated with subjective well-being, self-esteem and hope. This study is the first to explore whether attachment styles are related to personal recovery in this population.

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Serum immune markers and transition to psychosis in individuals at clinical high risk.

Brain Behav Immun

May 2023

National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, UK; King's College London, Institute of Psychiatry, Psychology and Neuroscience, Department of Psychosis Studies, London, UK.

Individuals at clinical high risk (CHR) for psychosis have been found to have altered cytokine levels, but whether these changes are related to clinical outcomes remains unclear. We addressed this issue by measuring serum levels of 20 immune markers in 325 participants (n = 269 CHR, n = 56 healthy controls) using multiplex immunoassays, and then followed up the CHR sample to determine their clinical outcomes. Among 269 CHR individuals, 50 (18.

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International Health Electives: defining learning outcomes for a unique experience.

BMC Med Educ

March 2023

Center for Educational Development and Research in Health Sciences (CEDAR), Lifelong learning, Education and Assessment Research Network (LEARN), University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Background: An International Health Elective (IHE) can be a unique learning experience for students. However, it has proven difficult to clearly define learning outcomes that capture the complexity of an IHE and are aligned with future professional performance. This study aimed to further define learning outcomes for IHEs in low- to middle-income countries (LMIC) from a student perspective.

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A smoking cessation intervention for people with severe mental illness treated in ambulatory mental health care (KISMET): study protocol of a randomised controlled trial.

BMC Psychiatry

February 2023

Department of Health Sciences and Amsterdam Public Health research institute, Faculty of Science, Vrije Universiteit Amsterdam, Van der Boechorststraat 7, 1081BT, Amsterdam, The Netherlands.

Background: Smoking among people with severe mental illness (SMI) is highly prevalent and strongly associated with poor physical health. Currently, evidence-based smoking cessation interventions are scarce and need to be integrated into current mental health care treatment guidelines and clinical practice. Therefore, the present study aims to evaluate the implementation and effectiveness of a smoking cessation intervention in comparison with usual care in people with SMI treated by Flexible Assertive Community Treatment (FACT) teams in the Netherlands.

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Concern for symptom exacerbation and treatment drop-out is an important barrier to the implementation of trauma-focused therapy (TFT), especially in people with a psychotic disorder. This study, which was part of a multicenter randomized controlled trial, investigated posttraumatic stress disorder (PTSD) symptom exacerbation during eye movement desensitization reprocessing (EMDR) therapy and prolonged exposure (PE) in a sample of 99 participants with PTSD and psychosis. Symptom exacerbations during the first four sessions (early exacerbation) and between-session exacerbations over the course of therapy were monitored using the PTSD Symptom Scale-Self Report.

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To study mental illness and health, in the past researchers have often broken down their complexity into individual subsystems (e.g., genomics, transcriptomics, proteomics, clinical data) and explored the components independently.

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Objective: The objective of this study was to gain insight into patients' experiences of how personal recovery (PR) is facilitated or hindered in the context of an early episode psychosis setting (Soteria). We thereby aimed to contribute to the understanding of how care settings may promote or hinder the process of PR in people with (acute) psychosis.

Method: This study used a qualitative method, consisting of semi-structured in-depth interviews with people who had been admitted to a Soteria house in the Netherlands.

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Article Synopsis
  • Adverse childhood experiences (ACE) significantly hinder educational achievements, particularly in individuals at clinical high risk of psychosis (CHR).
  • A study involving 344 CHR individuals and 67 healthy controls found that the CHR group had higher ACE rates, spent less time in education, and faced higher unemployment compared to healthy controls.
  • The research suggests that addressing ACE through early intervention programs can improve educational and vocational outcomes for CHR individuals, emphasizing the need for broader public health measures to prevent and mitigate the effects of ACE.
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Adding EMDR for PTSD at the onset of treatment of borderline personality disorder: A pilot study.

J Behav Ther Exp Psychiatry

June 2023

Parnassia Psychiatric Institute, Lijnbaan 4, 2512, VE, The Hague, the Netherlands; Erasmus School of Social and Behavioural Sciences, Burg. Oudlaan 50, 3062, PA, Rotterdam, the Netherlands. Electronic address:

Background And Objectives: Eye movement desensitization and reprocessing (EMDR) is an effective treatment for individuals suffering from posttraumatic stress disorder (PTSD). However, EMDR is not typically offered to people with PTSD who also meet the criteria for borderline personality disorder (BPD). This study examines the feasibility and clinical benefits of EMDR for PTSD delivered in addition to the onset of treatment as usual (TAU) for BPD.

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Objectives: Determinants of frailty are generally explored within context of somatic healthcare and/or lifestyle characteristics. To examine the impact of personality traits on change in frailty and the potential role of depression.

Methods: A 2-year follow-up study including 285 patients with a depressive disorder and 116 never-depressed controls.

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Prevalence of mental disorders in refugees and asylum seekers: a systematic review and meta-analysis.

Glob Ment Health (Camb)

June 2022

Department of Clinical, Neuro-, and Developmental Psychology and WHO Collaborating Center for Research and Dissemination of Psychological Interventions, Vrije Universiteit, Amsterdam, The Netherlands.

Background: Studies have identified high rates of mental disorders in refugees, but most used self-report measures of psychiatric symptoms. In this study, we examined the percentages of adult refugees and asylum seekers meeting diagnostic criteria for major depressive disorder (MDD), post-traumatic stress disorder, bipolar disorder (BPD), and psychosis.

Methods: A systematic literature search in three databases was conducted.

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Development and Validation of the 'Self-Efficacy in Dealing with Self-Harm Questionnaire' (SEDSHQ).

Int J Environ Res Public Health

December 2022

Department of Health, Sports & Welfare, Research Group Mental Health Nursing, Inholland University of Applied Sciences, 1081HV Amsterdam, The Netherlands.

Clinicians find it challenging to engage with patients who engage in self-harm. Improving the self-efficacy of professionals who treat self-harm patients may be an important step toward accomplishing better treatment of self-harm. However, there is no instrument available that assesses the self-efficacy of clinicians dealing with self-harm.

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Corrigendum to "Cognitive trajectories during and after electroconvulsive therapy in patients with MDE: Taking different perspectives" [J. Psychiatr. Res. 152 (2022) 132-140].

J Psychiatr Res

February 2023

University Psychiatric Hospital Duffel, VZW Emmaüs, Duffel, Belgium; Collaborative Antwerp Psychiatric Research Institute (CAPRI), Department of Biomedical Sciences, University of Antwerp, Belgium; Psychiatric Hospital Bethanië, Andreas Vesaliuslaan 39, 2980, Zoersel, Belgium.

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Background: To our knowledge, treatment of personality disorder (PD) comorbidity in autistic adults is understudied and is still in its infancy. We investigated the effectiveness of schema therapy (ST) for autistic adults with PD.

Method: A multiple case series design with 12 adults (aged 19-62 years) was used with baseline, exploration, ST (with cognitive behavioural and experiential techniques) and follow-up conditions.

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Speech Illusions in People at Clinical High Risk for Psychosis Linked to Clinical Outcome.

Schizophr Bull

March 2023

Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Background And Hypothesis: Around 20% of people at clinical high risk (CHR) for psychosis later develop a psychotic disorder, but it is difficult to predict who this will be. We assessed the incidence of hearing speech (termed speech illusions [SIs]) in noise in CHR participants and examined whether this was associated with adverse clinical outcomes.

Study Design: At baseline, 344 CHR participants and 67 healthy controls were presented with a computerized white noise task and asked whether they heard speech, and whether speech was neutral, affective, or whether they were uncertain about its valence.

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Pharmacogenetics (PGx) studies the effect of heritable genetic variation on drug response. Clinical adoption of PGx has remained limited, despite progress in the field. To promote implementation, the Dutch Pharmacogenetics Working Group (DPWG) develops evidence-based guidelines on how to optimize pharmacotherapy based on PGx test results.

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Background: Ketamine and its enantiomer esketamine represent promising new treatments for treatment-resistant depression (TRD). Esketamine induces acute, transient psychoactive effects. How patients perceive esketamine treatment, and which conditions facilitate optimal outcomes, remains poorly understood.

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Youth peer support workers (YPSWs) are young adults with lived experience of mental illness during childhood or adolescence who support young people receiving treatment in mental health services. The contributions made by YPSWs are a promising development to facilitate consumer-centered and recovery-oriented care. Although the youth peer support workforce is expanding rapidly, structurally embedding YPSWs in practice is challenging.

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Background: The incubus phenomenon is a paroxysmal sleep-related disorder characterized by the visuotactile sensation of a person or entity exerting pressure on one's thorax during episodes of sleep paralysis and (apparent) wakefulness. This terrifying phenomenon is relatively unknown even though a previous meta-analysis indicated a lifetime prevalence of 0.11 for individuals in the general population and of 0.

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Article Synopsis
  • Multiple studies indicate that compulsory community treatment (CCT) does not significantly improve clinical outcomes or reduce hospital admissions compared to voluntary care, yet many countries still implement it due to stakeholder support.
  • An integrative review examined the perceptions of various stakeholders—patients, significant others, mental health workers, and policymakers—about CCT, identifying a lack of input from policymakers in the existing literature.
  • Most stakeholders, especially relatives and mental health workers, tend to support CCT for its benefits in accessibility and ongoing patient contact, although there's widespread concern about the autonomy restrictions it imposes, with patients showing more hesitation towards CCT.
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