Clin Endocrinol (Oxf)
April 2006
Pediatric Endocrinology and Diabetes Unit, Robert Debré Hospital, Assistance Publique--Hôpitaux de Paris, Paris VII University, France.
Objective: The cause of posterior pituitary ectopia (PPE) with anterior pituitary hormone deficiencies is unknown. This disease is usually considered sporadic. The objective of this study was to improve the phenotypic characterization of children with PPE and growth hormone deficiency (GHD) to seek insight into the mechanisms underlying abnormal pituitary-gland development.
View Article and Find Full Text PDFClin Implant Dent Relat Res
September 2005
Department of Periodontology, Paris VII University, Paris, France.
Background: Although the predictability of endosseous dental implants is well documented, the restoration of the posterior region of the maxilla remains a challenge. The placement of short implants is one therapeutic option that reduces the need for augmentation therapy.
Purpose: The purpose of this retrospective study was to assess the survival rates of 6 to 8.
J Clin Orthod
June 2005
Department of Lingual Orthodontics, Paris VII University, Paris, France.
Br J Surg
May 2005
Department of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, Hospital Beaujon (AP-HP, Paris VII University), Clichy, France.
Background: The remnant left liver after right hepatectomy tends to rotate spontaneously into the right subphrenic space. This rotation might induce venous outflow impairment. The aim of this study was to assess immediate venous outflow in the left hepatic vein by intraoperative Doppler ultrasound (US) according to the position of the remnant liver.
View Article and Find Full Text PDFArch Otolaryngol Head Neck Surg
February 2005
Assistance Publique-Hôpitaux de Paris, Paris VII University, Lariboisière Hospital, Paris, France.
AJNR Am J Neuroradiol
January 2005
Department of Otorhinolaryngology-Head and Neck Surgery, Assistance Publique-Hôpitaux de Paris, Paris VII University, Lariboisière Hospital, France.
Background And Purpose: High recurrence rates and early recurrence have been reported for juvenile nasopharyngeal angiofibroma (JNA) involving the skull base. The purpose of this study was to evaluate the diagnostic accuracy of contrast-enhanced CT scanning for the detection of residual disease (RD) in the early postoperative course after surgical excision of JNA.
Methods: We retrospectively reviewed data in 20 male patients (mean age +/- SD, 15.
Auris Nasus Larynx
September 2004
Department of Otorhinolaryngology-Head and Neck Surgery, Assistance Publique-Hôpitaux de Paris, Paris VII University, Lariboisière Hospital, 2, rue Ambroise Paré, 75010 Paris, France.
Objective: To evaluate the prevalence as well as the management of primary facial nerve schwannoma (PFNS) presenting as vestibular schwannoma.
Methods: A retrospective review was carried out on 146 patients referred to and operated upon in our institution over a 5-year period for tumors of the internal auditory canal extending or not into the cerebello-pontine angle (TICA). A review of the literature included an extensive MEDLINE search of the literature since 1966 and careful inspection of the bibliography of each article.
J Biomed Mater Res A
November 2003
INSERM ERIT-M 0204, X. Bichat Hospital, University Paris VII & University Paris XIII, 75877 Paris Cedex 18, France.
The development of new materials for tissue engineering of skin substitutes requires an increasing knowledge of their interactions with human skin cells. Since carbohydrate recognition is involved in numerous biologic processes, including skin regeneration, the aim of this study was to identify sugar receptors expressed at the surface of human dermic and epidermic cells. Binding of fluorescent sugar-polyhydroxyethylacrylamide derivatives was analyzed by flow cytofluorimetry on cultured human skin fibroblasts, keratinocytes, and melanocytes.
View Article and Find Full Text PDFCan we still rely on the World Health Organization? It has not openly opposed the greed of the major global pharmaceutical companies, and its director-general, Gro Harlem Brundtland, has deferred to them.
View Article and Find Full Text PDFCirc Res
December 2002
Institut National de la Santé et de la Recherche Médicale Unit 541, IFR Circulation-Paris-Nord, Paris VII University, France.
Dystrophin has a key role in striated muscle mechanotransduction. In mice lacking the gene encoding for dystrophin (mdx mice), the absence of dystrophin and several other proteins of the dystrophin-glycoprotein complex induces a defect in flow (shear stress)-mediated NO-dependent dilation (FMD). Because the endothelium is essential for the adaptation of arteries to chronic changes in blood flow, the long-term consequences of this vascular deficiency might affect flow-induced vascular remodeling.
View Article and Find Full Text PDFJ Vasc Res
September 2002
INSERM, U348, IFR Circulation-Paris-Nord, Paris VII University, Hôpital Lariboisière, Paris, France.
Thromboxane A(2) (TxA2) is a potent proaggregating, vasoconstrictor agent produced in many physiological and pathological situations. Although mitogen-activated protein (MAP) kinases [MAPK (ERK1/2 and p38)] have been shown to be activated after endoperoxide/thromboxane receptor (TP) stimulation, no study has investigated their potential role in resistance arteries, especially in physiological conditions of pressure and flow in which the arteries can contract. Thus, responses to TP stimulation by the stable agonist U46619 were studied in isolated rat mesenteric resistance arteries (inner diameter 262 +/- 5 microm) mounted in an arteriograph.
View Article and Find Full Text PDFBr J Surg
June 2002
Department of Digestive Surgery, Bichat Hospital, Paris VII University, 46 rue Henri- Huchard, 75877 Paris Cedex 18, France.
Background: Lengthening of the mesentery by vascular division may be necessary to perform an ileal pouch-anal anastomosis without tension. The aim of this study was to compare, in fresh cadavers, the increase in mesentery length after division of the ileocolic pedicle (ICP) and the superior mesenteric pedicle (SMP).
Methods: Total colectomy was performed in 12 fresh cadavers, which were then randomly divided into two groups.
Hepatogastroenterology
October 2002
Department of Hepatobiliary and Digestive Surgery, Beaujon Hospital, Paris VII University, Clichy, France.
Background/aims: Surgical liver resection has been demonstrated in Asian countries to be the best therapeutic option in patients with hepatocellular carcinoma. Because the value of this treatment is still debated in Western countries, the aim of this paper was to report a European experience of resection for hepatocellular carcinoma.
Methodology: From 1990 to 1999, 239 men and 61 women aged from 15 to 77 years old underwent 328 resections including major resection in 138 (42%) cases.
Invest Ophthalmol Vis Sci
April 2002
Ophthalmology Service, Bichat Hospital, Rothschild Foundation, Paris VII University, Paris, France.
Purpose: To determine the ablation depths of customized myopic excimer laser photoablations performed to change corneal asphericity after laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK).
Methods: A mathematical model of aspheric myopic corneal laser surgery was generated. The initial corneal surface was modeled as a conic section of apical radius R(1) and asphericity Q(1).
Vox Sang
February 2002
French National Blood Service, Paris, France Paris VII University, Paris, France.
Background And Objectives: Since 1 April 1998, all cellular blood components in France have been leucoreduced. The current French standard is < 1 x 10(6) white blood cells (WBC) per unit with a 95% confidence that at least 97% of units will meet this standard.
Materials And Methods: Quality control (QC) data for leucoreduced cellular blood components were collected from the 41 French blood centres over a 5-month period.
FASEB J
January 2002
Institut National de la Santé et de la Recherche Médicale (INSERM) U 541, IFR-Circulation-Paris-Nord, Paris VII University, Paris, France.
The intermediate filament desmin has a key role in the integrity and contractility of skeletal and cardiac myocytes. Its absence or aggregation leads to cardiomyopathies. In arteries desmin is distributed heterogeneously; vascular disorders might also occur in its absence.
View Article and Find Full Text PDFLiver Transpl
November 2001
Department of Digestive Surgery and Transplantation Unit, Paris VII University, Beaujon Hospital, Clichy, France.
As promoters of orthotopic liver transplantation (OLT) with preservation of caval flow, we reviewed our 8-year experience to assess the feasibility and limits of this technique. Preservation of caval flow during OLT, which improves intraoperative hemodynamic stability, was not considered feasible in a significant proportion of transplant recipients. When transient clamping of caval flow is required, causes and consequences of this clamping during all phases of the procedure were not reported.
View Article and Find Full Text PDFJ Bone Joint Surg Br
August 2001
Robert Debré Hospital, Denis Diderot-Paris VII University, France.
We report the results of 116 consecutive displaced extension supracondylar fractures of the elbow in children treated during the first two years after the introduction of the following protocol; closed reduction under general anaesthesia with fluoroscopic control and lateral percutaneous pinning using two parallel pins or, when closed reduction failed, open reduction and internal fixation by cross-pinning. Eight patients were lost to follow-up during the first postoperative year. The mean follow-up for the remaining 108 was 27.
View Article and Find Full Text PDFEur J Immunol
September 2000
Department of Immuno-Hematology, Hematology Institute of Paris VII University, Hôpital Saint-Louis, France.
We evaluated the B cell memory pool among blood B cells from 20 patients with common variable immunodeficiency (CVID). CD27+ B cell number was normal or increased in 6 patients (with 95% CD27+ B cells in 1 patient) and decreased in 14 patients. In 13 or 15 patients studied, the CD27 molecule was detectable on less than 50% IgG or IgA B cells, indicating a defect in the maturation of these memory cells.
View Article and Find Full Text PDFJ Bone Joint Surg Br
July 1999
Robert Debré Hospital, Assistance Publique-Hôpitaux de Paris, Bichat Medical Faculty, Paris VII University, France.
In order to define the prognostic factors in Perthes' disease in children older than 12 years, we reviewed 15 patients at the end of growth who were aged 12.1 to 14 years at presentation. The patients with the worst long-term prognosis (Stulberg class V) were compared with the others for age, skeletal maturity and remaining growth (Oxford method), as well as Catterall and Waldenström classifications at presentation.
View Article and Find Full Text PDFJ Pediatr Orthop B
July 1997
Department of Orthopaedic Surgery, Robert Debré Hospital, Xavier Bichat Medical faculty, Paris VII University, France.
We treated 34 femoral shaft fractures in 32 children with elastic intramedullary nailing using titanium rods. The 24 boys and 8 girls ranged from 6-17 years. All fractures united.
View Article and Find Full Text PDFJ Clin Periodontol
July 1997
Department of Periodontology, School of Dentistry, Paris VII University, France.
30 periodontally compromised adult subjects with mandibular buccal class II furcation defects were recruited for this study. All selected defects were treated according to the biological principles of guided tissue regeneration. The subjects were randomly assigned to 2 parallel groups.
View Article and Find Full Text PDFRev Rhum Engl Ed
January 1996
National Institute for Health and Medical Research, Paris VII University, France.
Study Objectives: Long term prognosis of systemic juvenile chronic arthritis range from full recovery to extremely severe crippling polyarthritis. An association between HLA-DR4 and a poor articular outcome has been reported. We studied the frequencies of class I, class II, and class III antigens according to clinical and laboratory test findings, particularly presence of antibodies to type II collagen, in a cohort of 108 patients.
View Article and Find Full Text PDFRev Rhum Engl Ed
June 1995
Rheumatology Department, Paris VII University, Bichat Teaching Hospital, France.
Neuropathol Appl Neurobiol
June 1994
Department of Bacteriology and Virology, Saint-Louis Hospital, Paris VII University, France.
The increased incidence of primary central nervous system malignant non-Hodgkin's lymphomas (PCNSL) in HIV- and non-HIV-infected patients and the demonstration of Epstein-Barr virus (EBV) in these tumours may indicate relationships between PCNSL and EBV. Consequently expression of EBV-induced antigens and cellular markers were studied in 11 HIV-infected and seven non-infected patients by in situ hybridization (ISH) and immunocytochemistry in monoclonal B cell PCNSL. In HIV-infected patients EBV genome was present in 9/11 cases, LMP in 11/11 cases and EBNA2 in 10/11 cases.
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