Fredholm theory for the mean first-passage time of integrate-and-fire oscillators with colored noise input.

We develop a method to investigate the effect of noise timescales on the first-passage time of nonlinear oscillators. Using Fredholm theory, we derive an exact integral equation for the mean event rate of a leaky integrate-and-fire oscillator that receives constant input and temporally correlated noise. Furthermore, we show that Fredholm theory provides a unified framework to determine the system scaling behavior for small and large noise timescales.

Toward standard practices for sharing computer code and programs in neuroscience.

Computational techniques are central in many areas of neuroscience, and are relatively easy to share. This paper describes why computer programs underlying scientific publications should be shared, and lists simple steps for sharing. Together with ongoing efforts in data sharing, this should aid reproducibility of research.

Location and identity memory of saccade targets.

While the memory of objects' identity and of their spatiotopic location may sustain transsaccadic spatial constancy, the memory of their retinotopic location may hamper it. Is it then true that saccades perturb retinotopic but not spatiotopic memory? We address this issue by assessing localization performances of the last and of the penultimate saccade target in a series of 2-6 saccades. Upon fixation, nine letter-pairs, eight black and one white, were displayed at 3° eccentricity around fixation within a 20° × 20° grey frame, and subjects were instructed to saccade to the white letter-pair; the cycle was then repeated.

Introspective duration estimation of reactive and proactive motor responses.

The metajudgment of motor responses refers to our ability to evaluate the accuracy of our own actions. Can humans metajudge the duration of their Reaction Times (RTs) to a light-flash and the accuracy of their reproduction of a reference time interval bounded by two light flashes (Anticipatory Response Time, ART)? A series of four distinct experiments shows that RT_Meta and ART_Metajudgments are possible but with accuracies about x2.4 and x3 poorer than the corresponding RT and ART ones.

The planning of a sequence of saccades in pro- and antisaccade tasks: influence of visual integration time and concurrent motor processing.

Previous studies have shown that a saccade is coded in a specific reference frame according to its goal: to aim for a new object or to explore an object which has already been fixated. In a two saccade sequence, the second saccade aiming for a new object is programmed in a retinocentric reference frame in which the spatial location of the second object is stored in spatial memory before the first saccade and updated after its execution. The second saccade exploring the same object is coded in an oculocentric reference frame in which object size is directly transformed into a fixed motor vector, encoded in motor memory before the first saccade and simply applied after its execution.

Visual versus motor vector inversions in the antisaccade task: a behavioral investigation with saccadic adaptation.

In the antisaccade task, subjects must execute an eye movement away from a visual target. Correctly executing an antisaccade requires inhibiting a prosaccade toward the visual target and programming a movement to the opposite side. This movement could be based on the inversion of the visual vector, corresponding to the distance between the fixation point and the visual target, or the motor vector of the unwanted prosaccade.

Saccade dynamics before, during, and after saccadic adaptation in humans.

Purpose: When saccade amplitude is systematically inadequate relative to the desired target position, the saccadic system adaptively modifies the amplitude of subsequent saccades so as to recover precise targeting capabilities. The effect of saccadic adaptation on saccade metrics (amplitude, direction) is well documented, but the effect on dynamics (velocity, duration, acceleration, deceleration) remains to be fully elucidated.

Methods: The dynamics of adapted saccades were compared with that of baseline saccades of similar amplitudes.

Motor space structures perceptual space: evidence from human saccadic adaptation.

Saccadic adaptation is the progressive correction of systematic saccade targeting errors. When a saccade to a particular target is adapted, saccades within a spatial window around the target, the adaptation field, are affected as a function of their distance from the adapted target. Furthermore, previous studies suggest that saccadic adaptation might modify the perceptual localization of objects in space.