A survey on neoplasia in domestic species over a 40-year period from 1935 to 1974 in the Republic of South Africa. IV. Tumours occurring in Equidae.

A survey was carried out on the neoplasms of horses, donkeys and mules which are recorded in the registration files of the Section of Pathology of the Veterinary Research Institute, Onderstepoort, in the Republic of South Africa, over a 40-year period from 1935 to 1974. A total of 378 tumours are recorded, 339 of which were in horses, 32 in mules and 7 in donkeys. Sarcoids (38%), squamous cell carcinomas (23,5%), fibromas (8,2%), melanomas (8,0%), papillomas (4,5%), fibrosarcomas (3,4%) and lymphosarcomas (3,0%) accounted for 88,6% of the total.

Focal dermal hypoplasia: ocular manifestations in a male.

Focal dermal hypoplasia (Goltz Syndrome) is a rare congenital disorder resulting from ectodermal and mesodermal dysplasia. It involves ocular tissues in over 40% of cases. Considered to be X-linked dominant, the disorder characteristically occurs in females.

Exophthalmos, global luxation, rapid weight gain: differential diagnosis.

Exophthalmos is an uncommon finding in the clinical setting; exophthalmos with global luxation is distinctly rare. Although the differential diagnosis of exophthalmos can be extensive, the most common causes are thyroid dysfunction and orbital neoplasia. We recently encountered a patient with exophthalmos and global luxation, the onset of which coincided with a weight gain of 45.

Evidence for papillomaviruses in ocular lesions in cattle.

Negatively stained preparations of various ocular lesions, generally considered to be precursors to bovine ocular squamous cell carcinoma, were subjected to electron microscopic examination for viruses. Lesions examined included five conjunctival plaques, an acanthotic lesion from an eyelid, 15 conjunctival papillomas, two papillomas of the eyelid and two keratinised elongated proliferative lesions of the eyelid (cutaneous horns). Eight lesions contained particles that resembled papillomaviruses.

Biomicroscopy of papillae associated with hard contact lens wearing.

We studied the macrostructural characteristics of papillary changes of the upper tarsal conjunctiva associated with the wearing of polymethyl methacrylate (PMMA) contact lenses. Fifty subjects with elevated conjunctival papillae greater than 0.3 mm in diameter were studied.

Clinical survey of tumours and tumour-like lesions in horses in south east Queensland.

The results of a retrospective survey of tumours and tumour-like lesions encountered in horses in a veterinary practice in south east Queensland between 1956 and 1978 are presented. Forty-two per cent of the lesions were examined histologically. The most commonly occurring neoplasms were the equine sarcoid, papilloma and squamous cell carcinoma of the eye and external genitalia.

Papillomatosis of conjunctiva and adnexa in dogs.

Ocular or periocular papillomatosis was diagnosed in seven dogs. The periocular tumors (in 4 dogs) were located on the eyelids or the mucocutaneous junctions of the eyelids. Six of the tumors were removed surgically, using either superficial keratectomy and conjunctival dissection or lid resection techniques; the seventh was biopsied but not removed.

Inverted papilloma of the conjunctiva.

We encountered inverted papilloma of the conjunctiva in three cases. To the best of our knowledge, this tumor, which typically involves the nose, paranasal sinuses, and lacrimal sac, has not been described previously in the conjunctiva. Two of the tumors occurred as purely inverted lesions of the inner canthal region )caruncle and plica) and the third as a mixed inverted-exophytic papilloma over the tarsus.

[34 epibulbar malignant tumours (author's transl)].

Based on a study of 34 cases, the authors make therapeutical and diagnostical references concerning the epibulbar malignant tumours. These were met with a frequency of 10% of the total amount of the malignant tumours of the visual apparatus. The most frequent setting were at the level of the bulbar conjunctiva and of the sclero-corneal limb, especially in front of the opening of the palpebral slit and in the temporal area.

The role of cryosurgery in external ocular and periocular disease.

This preliminary report suggests that cryosurgery has a definite place in the management of certain external periocular and ocular problems. Cryosurgery for basal or squamous cell carcinoma of the lid is easily performed, gives excellent cosmetic results, and has a low recurrence rate. It is not recommended for lesions involving the fornices, or sclerotic and morphea-type basal cell carcinomas.

[Treatment of malignant lid tumours by intrapalpebral injection of urea (author's transl)].

36 malignant tumours of the eyelids (basaliomas, basal-cell carcinomas and squamous-cell carcinomas) have been treated by intrapalpebral injections of a 5% to 25% solution of urea as recommended by E.D. Danopoulos.

[The clinical misdiagnosis of chalazion (author's transl)].

Between 1966 and 1974, 1260 lidtumours were sent to the histological laboratory of the University Eye Hospital Hamburg. The clinical diagnosis "chalazion" in 138 cases could not be verified histologically in 33 cases. Other benign lesions were diagnosed 23 times and malignant lesions in 10 cases (4 times a Meibom's sebaceous cell carcinoma).

[Cryotherapy of eyelid and conjunctival tumors].

Report is given of cryobiological principles, technique and results of cryotherapy for eyelid or conjunctival tumors in 181 cases. In the majority of cases they were basaliomas. In all cases the therapy was successful.

Lid lesions of childhood: a histopathologic survey at the Wilmer Institute (1923-1974).

This study reports 398 excised eyelid lesions in 385 children from birth through age 15. This study analyzes and discusses the clinical and histological features of the 34 types of lesions which were encountered. This tabulation serves as a guide to the physician when confronted with lid lesions in children as to the types of lesions which may be found.