411 results match your criteria: "Panzhihua University[Affiliation]"

Article Synopsis
  • This study looked at a special molecule called H19 to see how it behaves in people with a disease called systemic lupus erythematosus (SLE).
  • The researchers found that H19 levels were higher in SLE patients, while another molecule called miR-19b had lower levels in their blood.
  • They discovered that H19 might make certain immune cells unhealthy by causing them to die and react more, which could help understand why SLE happens.
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Amid an era of rapid globalization and technological advancement, translation technologies stand as valuable assets for college students to enhance accuracy and efficiency in the translation process. However, the adoption and acceptance of these technologies are contingent on several psychological factors, which are underexplored in the academic field. This study, populated by a cohort of 397 college students, employs a multiple-item questionnaire measuring computer self-efficacy, learning motivation, cognitive engagement, and the behavioral intention to utilize translation technologies.

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The present study explored that the effects and its possible mechanisms of ring finger protein 20 (RNF20) in Postoperative survival rate of liver cancer in clinical. All the serum samples were collected from our hospital. Quantitative polymerase chain reaction (PCR) and microarray analysis, and RNA pull down assay were used in this study.

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The magnetization mechanism of Co-doped BaTiO ultrathin films is a subject of debate, which results in difficulties with the design of new multiferroics based on BaTiO matrixes. With the aid of a first-principles approach, it was observed that when the interstitial site and Ti vacancy were filled with Co, the configuration behaved in a nonmagnetic manner, indicating the significance of the Co content. Moreover, in the case of Co substituting two neighboring Ti atoms, when a direct current field was applied in the [100] direction, the magnetic domains excluding those in the [100], [010], and [001] directions were directed away.

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Background: The causal genetic relationship between common parenteral manifestations of inflammatory bowel disease (IBD) and urolithiasis remains unclear because their timing is difficult to determine. This study investigated the causal genetic association between IBD and urolithiasis using Mendelian randomization (MR) based on data from large population-based genome-wide association studies (GWASs).

Methods: A two-sample MR analysis was performed to assess the potential relationship between IBD and urolithiasis.

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The pathogenesis of glioma has remained unclear. In this study, it was found that high expression of the outer dense fibers of sperm tail 3B (ODF3B) in gliomas was positively correlated with the grade of glioma. The higher the grade, the worse the prognosis.

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Integrative Single Cell Atlas Revealed Intratumoral Heterogeneity Generation from an Adaptive Epigenetic Cell State in Human Bladder Urothelial Carcinoma.

Adv Sci (Weinh)

June 2024

Department of Urology, Hubei Key Laboratory of Urological Diseases, Department of Biological Repositories, Human Genetic Resources Preservation Center of Hubei Province, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China.

Intratumor heterogeneity (ITH) of bladder cancer (BLCA) contributes to therapy resistance and immune evasion affecting clinical prognosis. The molecular and cellular mechanisms contributing to BLCA ITH generation remain elusive. It is found that a TM4SF1-positive cancer subpopulation (TPCS) can generate ITH in BLCA, evidenced by integrative single cell atlas analysis.

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Preparation of an Inorganic All-Solid-State Electrochromic Device with Excellent Open-Circuit Memory.

ACS Appl Mater Interfaces

April 2024

School of Material Science and Engineering, Xi'an University of Technology, No. 5 Jinhua South Road, Xi'an, Shaanxi 710048, P. R. China.

Due to the spontaneous transport of small-sized cations and redox reactions under open circuit conditions, the currently reported coloring electrochromic devices (ECDs) may self-bleach easily. The resulting ECDs exhibit poor open-circuit memory, which limits their applications in static display advertisement. By constructing energy barriers to effectively control small-sized cation transport, the redox reaction could be suppressed, thereby inhibiting the self-bleaching of ECDs.

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Article Synopsis
  • A pathogen linked to serious infections, particularly from sea contact, is increasingly affecting non-coastal regions due to climate change and seafood trade.
  • The report details a successful case of necrotizing wound treatment in an inland city in southwest China caused by this pathogen.
  • It also reviews the epidemiology of the pathogen in China and highlights ongoing vaccine research to aid in diagnosis and treatment.
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Transcriptome data-based screening of potential host of genetic transformation for a blue-hued Bougainvillea transgene.

Genet Mol Biol

March 2024

Panzhihua University, Faculty of Biological and Chemical Engineering, Department of Biological Engineering, Panzhihua, Sichuan, P.R. China.

Bougainvillea is a popular ornamental plant. Although Bougainvillea is abundant in germplasm resources, cultivars and flower colors, there is no rare blue colour varieties, due to the absence of delphinidin-based anthocyanins. This study analyzed the Bougainvillea leaf and bract transcriptome to select hosts of genetic transformation that would be suitable for the accumulation of delphinidin.

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The significant threat posed by the high toxicity of heavy metals and antibiotics in water pollutants has prompted a growing emphasis on the development of highly efficient removal methods for these pollutants. In this paper, flexible electrospinning polyacrylonitrile (PAN) nanofiber-supported CdBiS was synthesized via a hydrothermal method, followed by amination treatment with diethylenetriamine (DETA). The as-prepared CdBiS/NH-PAN nanofiber, enriched with sulfur vacancies, demonstrated outstanding visible-light trapping ability and a suitable band gap, leading to efficient separation and transport of photogenerated carriers, ultimately resulting in exceptional photocatalytic capability.

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Background: Chronic obstructive pulmonary disease (COPD) is a common respiratory disease and the third leading cause of death worldwide. Previous evidence has shown that acupuncture may be an effective complementary alternative therapy for stable COPD. However, large-sample, rigorously designed long-term follow-up studies still need to be completed.

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Morels (Morchella spp.), which are cultivated only in a few regions of the world, are edible mushrooms known for their various properties including antioxidation, immune regulation, antiinflammation, and antitumor effects. Polysaccharides from Morchella are principally responsible for its antioxidant activity.

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Background: The incidence and recurrence rate of acute pancreatitis (AP) continues to increase worldwide. The risk of AP attack and recurrence is closely related to the patient's health literacy. Previous studies have shown that AP patients had low levels of health literacy.

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Explainable machine learning in outcome prediction of high-grade aneurysmal subarachnoid hemorrhage.

Aging (Albany NY)

March 2024

Department of Neurosurgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, Jiangxi, China.

Article Synopsis
  • - The study developed a machine learning model to predict outcomes in patients with high-grade aneurysmal subarachnoid hemorrhage (aSAH), emphasizing the importance of personalized treatment and using SHapley Additive exPlanations (SHAP) for interpretation.
  • - Data from 421 high-grade aSAH patients were used, and the random forest model outperformed others, achieving an AUC of 0.867, with significant prognostic features including higher WFNS grade, advanced age, and the impact of coiling embolization on outcomes.
  • - The findings highlight the effectiveness of machine learning in predicting patient prognosis and stress the value of SHAP analysis for understanding the model's predictions and aiding clinical decisions.
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With the advancement of information technology and artificial intelligence, translation technologies have seen rapid development in language services and increasing integration in higher education. However, research on factors affecting students' acceptance of these technologies remains limited. This study intends to formulate and test an extended Technology Acceptance Model (TAM) incorporating computer self-efficacy and perceived enjoyment to investigate students' adoption of translation technologies.

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Comprehensive utilization of two industrial wastes by leaching pyrite cinder with titanium dioxide waste acid was proposed by using response surface methodology of the Box-Behnken design method. The effects of leaching conditions such as leaching temperature, leaching time, and waste acid/pyrite cinder ratio on the leaching yield were examined. The prediction model including the leaching variables with a good fitting result was established to predict the leaching yield or optimize the leaching variable values.

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The production process of the metallurgical industry generates a significant quantity of hazardous waste. At present, the common disposal method for metallurgical hazardous waste is landfilling, which synchronously leads to the leaching of toxic elements and the loss of valuable metals. This paper presents a comprehensive review of the research progress in the harmless treatment and resource utilization of stainless steel dust/sludge (including stainless steel dust and stainless steel pickling sludge) and aluminum ash (including primary aluminum ash and secondary aluminum dross), which serve as representative hazardous wastes in ferrous metallurgy and nonferrous metallurgy, respectively.

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Article Synopsis
  • This study investigates how microhabitat features influence the distribution and functional traits of a high-elevation lizard species in the Namtso watershed of China, emphasizing the importance of intraspecific variations.
  • Findings reveal that males, females, and juveniles of the lizard display distinct functional traits shaped by different microhabitat variables, like illuminance and air temperature, which also determine their distribution.
  • The results highlight the need to consider intraspecific trait variation in ecological studies and support efforts to conserve diverse microhabitat features to maintain this variation within the species.
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When it comes to the environmental costs, environmental economists have tried to study the effects of the foreign direct investment-growth nexus, but they have ignored the crucial role that financial development and technical innovation play. Massive increases in energy consumption have contributed to environmental degradation in the BRICS nations, which have experienced rapid IND due to their robust economies. This study uses data from 1990 to 2021 to examine the relationship between carbon emissions in BRICS member nations and factors such as FDI, technological innovation, and economic growth.

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Epigenome-wide DNA methylation analysis of late-stage mild cognitive impairment.

Front Cell Dev Biol

January 2024

Institute of Neuroscience, Panzhihua University, Panzhihua, China.

Patients with late-stage mild cognitive impairment (LMCI) have a higher risk of progression to Alzheimer's disease (AD) than those with early-stage mild cognitive impairment (EMCI). However, previous studies have often pooled EMCI and LMCI patients into a single MCI group, with limited independent investigation into the pathogenesis of LMCI. In this study, we employed whole-genome methylation association analysis to determine the differences in peripheral blood methylation profiles between 663 cognitive aging (CN) and 554 LMCI patients.

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This study was conducted to explore cinobufotalin's effects and related mechanisms on serum MMP-2, MMP-9, Beclin1, and LC3-II in advanced non-small-cell lung cancer (NSCLC) patients. For this purpose, 150 patients with advanced NSCLC in our hospital from Jan. 2020 to Feb.

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The heat transfer of a slab is significantly influenced by roll contact during the continuous casting process. The influence of roll contact calculation methods on the predicted heat transfer results has not been previously investigated. In this work, the non-uniform solidification of the wide-thick slab was studied with a 2D heat transfer model using real roll contact method (R.

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Background: Phosphatidylinositol 3-kinase (PI3K) inhibitors belong to the class of drugs that inhibit the activity of the PI3K protein, which is commonly overexpressed in breast cancer cells. However, there is a need to summarize the evidence to provide conclusive advice on the benefit of PI3K inhibitors in breast cancer patients. Therefore, this review assessed the effectiveness and safety of the PI3K inhibitors amongst breast cancer patients.

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Enhanced catalytic performance of penicillin G acylase by covalent immobilization onto functionally-modified magnetic Ni0.4Cu0.5Zn0.1Fe2O4 nanoparticles.

PLoS One

January 2024

Vanadium and Titanium Resource Comprehensive Utilization Key Laboratory of Sichuan Province, College of Vanadium and Titanium, Panzhihua University, Panzhihua, 617000, P.R. China.

With the emergence of penicillin resistance, the development of novel antibiotics has become an urgent necessity. Semi-synthetic penicillin has emerged as a promising alternative to traditional penicillin. The demand for the crucial intermediate, 6-aminopicillanic acid (6-APA), is on the rise.

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