Comparative Assessment of Blood Parameters Including RBC, Hb, PCV, Red Cell Indices, Serum Ferritin, and Salivary Candidal Growth in Female Patients with Iron Deficiency Anemia and Iron Deficiency.

Background: Iron deficiency anemia (IDA) is a microcytic-hypochromic anemia prevalent in African and South Asian countries including India. Along with systemic, it presents various oral manifestations that can be diagnosed in dental setups. Literature suggests that there is a state of iron deficiency before it manifests as anemia, which eventually creates an immunodeficient body state that predisposes to various opportunistic infections such as oral candidiasis.

Evaluation of Displacement with Rapid Maxillary Expansion, Miniscrew-Assisted Rapid Maxillary Expansion, and Miniscrew-Assisted Rapid Maxillary Expansion Combined with Micro-Osteoperforations: A Comparative Finite Element Analysis.

Background And Objectives: Maxillary expansion is one of the most commonly advocated treatment approaches for the management of the maxillary deficiency in the transverse plane and is possible because of the presence of mid-palatal suture. This finite element method (FEM) study was taken to evaluate the stress pattern and displacement in the screw and its adjacent structures used in three different treatment modalities, such as rapid maxillary expansion (RME), mini-implant-assisted rapid palatal expansion (MARPE), and MARPE in conjunction with micro-osteoperforations.

Materials And Methods: An adult human dried skull, cone-beam computed tomography (CBCT) of the skull, and FEM and associated software (GEOMAGIC) were included.

Evaluating the pain at site, onset of action, duration and anesthetic efficacy of conventional, buffered lidocaine, and precooled lidocaine with intraoral cryotherapy application in patients with symptomatic irreversible pulpitis: A clinical study.

Aim: Injection pain and incomplete anesthesia can lead to procedural failure, causing fear and anxiety among patients. The aim of the study was to compare and evaluate pain at the site, the onset of action, duration, anesthetic efficacy, and success rates of conventional, buffered, and precooled 2% lidocaine of an inferior alveolar nerve block (IANB) in symptomatic irreversible pulpitis (SIP).

Materials And Methodology: In this double-blind, randomized clinical trial, 45 patients with deep carious lesions having moderate-to-severe pain in the mandibular first molar teeth were selected.

Exfoliated Oral Mucosal Cell Micronucleus Frequency Evaluation in Healthy Individuals, Tobacco Users, and Patients with Potentially Malignant Disorders: An Analytical Comparative Study.

Objective: Assessing the prevalence of exfoliated oral mucosal cell micronuclei in tobacco smokers, healthy persons, and patients with potentially malignant diseases (PMDs). A critical comparative investigation.

Materials And Procedures: The study included 80 participants divided into four groups: healthy persons, tobacco users without any clinically noticeable oral lesions, patients with leukoplakia, and patients with oral submucous fibrosis (OSMF).

Precision Medicine in Periodontics: A Literature Review.

Periodontitis, a widespread health issue, requires effective prevention and management strategies due to its increasing prevalence and detrimental social consequences. The chronic inflammation associated with periodontitis also exacerbates systemic conditions, emphasizing the need for advanced approaches in addressing this public health concern. The traditional methods of periodontal diagnosis, which primarily rely on clinical indicators such as pocket depth, clinical attachment loss, mobility, and radiographic measurements of alveolar bone loss, have limitations in guiding therapy due to the intricate and multifaceted nature of periodontal diseases.

A Comparative Evaluation of Clinical Efficacy of Topical Amlexanox and Triamcinolone Acetonide in Oral Lichen Planus.

Background: Oral lichen planus (OLP) is a chronic mucocutaneous disease affecting the general population, with its exact etiology remaining unknown. This condition is characterized by T-cell mediated autoimmunity wherein auto-cytotoxic CD8+ T cells precipitate basal cell apoptosis in the oral epithelium. Conventionally, corticosteroids have been the mainstay of treatment for OLP, necessitating the exploration of alternatives to mitigate long-term corticosteroid-related adverse effects.

Evaluation of Crestal Bone Levels using Simvastatin as an Adjuvant Around Immediate Implants - A Clinico Radiographic Study.

Objective: Simvastatin was used as an adjuvant medication in this clinico-radiographic investigation to assess the impact on crestal bone levels around immediate implantation.

Materials And Methods: A randomized controlled trial with 50 patients who needed an implant placed right away was done. Simvastatin was used as an adjuvant in groups ((Group A), whereas group (Group B)) served as the control group for the participants.

Assessment of Postoperative Edema in Different Bone Graft Cases in Vertical Defects in Periodontal Surgery: An Original Research.

Background: To replace missing periodontal tissues in vertical defects during periodontal surgery, bone graft materials are frequently used. A frequent occurrence that can affect healing outcomes is postoperative edema. The purpose of this study was to evaluate postoperative edema in various vertical bone graft defects following periodontal surgery.

Efficacy of diode lasers in oral verrucous hyperplasia: A case series.

Oral verrucous hyperplasia (OVH) is a potentially malignant lesion that may transform into an oral cancer. Cases without local metastases can be conservatively managed with local excision, laser therapy, photodynamic therapy, chemotherapy, etc. The aim of this article is to present a case series showing treatment outcomes of OVH excised with laser.

Role of Placental Extracts in Periodontal Regeneration: A Literature Review.

Periodontium is a specialized tissue surrounding the teeth. It is made up of the gingiva, periodontal ligament, cementum, and alveolar bone. The healing of periodontal tissues when infected occurs through repair and regeneration.

Marsupialization of odontogenic keratocyst using thermoform surgical splint in a pediatric patient, with 3-year follow-up.

Odontogenic keratocyst (OKC), also known as keratocystic odontogenic tumor, is categorized as one of the developmental epithelial cysts, which accounts 10%-20% of all cystic lesions in jaws. Considering its high recurrence rate, combative treatment modalities such as enucleation and jaw resection are suggested. This case report aims to emphasize clinical, radiological and histological overview of OKC with conservative approach marsupialization using thermoform surgical splint in a 9-year-old female patient with no recurrence at 3-year follow-up.

Maresins: The Mainstay in Periodontal Resolution.

Not much was known about the resolution of inflammation until the recent past when significant breakthroughs led to the unveiling of the exact mechanism of this. It is now known that the resolution of inflammation involves specific mediators of resolution such as lipoxins, protectins, resolvins, and maresins, making it an active process. Of these mediators, maresins are the latest discovery.

Horoscopic role of CD105 (Endoglin) in progression of oral lichen planus: An immunohistochemical study.

Context: Role of CD105(Endoglin) in Pathogenesis and progression of OLP.

Aim: To assess the role of neoangiogenesis in the progression of OLP by determining the expression of CD105 in OLP and normal mucosa.

Settings And Design: The present study includes a total of 70 formalin-fixed paraffin-embedded blocks of which the study group comprises 50 tissue sections histopathologically confirmed as OLP.

Multidisciplinary Approach for the Management of Dilacerated Permanent Maxillary Incisor: A Case Report.

Unlabelled: Dilaceration is an abrupt deviation along the long axis of the tooth, which may be observed between the crown, root, or both. Management of such teeth poses a unique challenge to the clinician due to its position within the esthetic zone. This case report describes the management of impacted maxillary central incisor with severe root dilacerations (90° angulation and crown directed toward the anterior nasal spine).

Morphometric analysis of basal cells of oral epithelium in predicting malignant transformation of oral potentially malignant disorders in patients with tobacco chewing habit.

Background: Oral potentially malignant disorders (OPMDs) are a heterogenous group of disorders which precede the development of oral cancer. These are characterized by increased risk of malignant transformation to Oral cancer.

Aims & Objectives: In this study, an attempt has been made to assess the morphological alterations of the nuclei of the basal cells in OPMDs and oral squamous cell carcinoma (OSCC).

Efficacy of Improvised Topical Zinc (1%) Ora-Base on Oral Mucositis during Cancer Chemo-Radiation-A Randomized Study.

Oral mucositis refers to erythematous and ulcerative lesions of oral mucosa during chemo/radiotherapy. Treatment modalities were directed towards reduction in severity of oral mucositis. Zinc plays an important role to retard oxidative processes and is considered as the critical component in wound healing.

A Comparative Evaluation on the Effect of Oral Zinc 50 mg with or without 0.1% Triamcinolone Orabase on Oral Lichen Planus.

Background: Lichen planus is a T-cell-mediated autoimmune disease, in which CD8+ T-cells releases the cytokines such as tumor necrosis factor-alpha and interleukin-12 disrupting basement membrane integrity. Treatment modalities were directed toward the relief in signs and symptoms and preventing recurrences. Zinc activates caspase-3 and DNA fragmentation, resulting in the apoptosis of keratinocytes.

Efficacy of Low-level Laser Therapy, Hyaluronic Acid Gel, and Herbal Gel as Adjunctive Tools in Gingivectomy Wound Healing: A Randomized Comparative Clinical and Histological Study.

Introduction Gingival overgrowth is usually an inflammatory response to plaque present on tooth surfaces. The other causes could be drugs and other systemic conditions. When the local factors are responsible and subgingival scaling does not help, gingivectomy is performed.

Evaluation of surgical scalpel versus semiconductor diode laser techniques in the management of gingival melanin hyperpigmentation: A split-mouth randomized clinical comparative study.

Background: "Black gums" due to melanin pigmentation of the gingiva is one reason for the demand of cosmetic therapy. Clinicians are often faced with challenge to achieve gingival esthetics in such cases because of its recurrence. Although many procedures were described in literature for gingival depigmentation, only few are mentioning about the intensity of repigmentation.

Comparison of efficacy of probiotics versus tetracycline fibers as adjuvants to scaling and root planing.

Context: Both gingivitis and periodontitis are due to the detrimental effects of the microbe-laden biofilm. The mainstay of periodontal treatment is, therefore, the disruption of this biofilm by scaling and root planing (SRP). Other treatment protocols such as systemic antimicrobials have been administered as adjuvants after scaling and root planning.

A Meta-analysis on efficacy of auto fluorescence in detecting the early dysplastic changes of oral cavity.

Background: Light-based detection agents using autofluorescence may be helpful in the detection of early dysplasia, which would otherwise be misdiagnosed as nondysplastic by conventional oral examination (COE) with white light. Visually-enhanced lesion scope (VELscope) is one of such an aid used for the purpose. A meta-analysis was carried out on the sensitivity and specificity of VELscope that would enable in providing evidence of its usage in oral dysplasia.

An update on investigations of autoimmune diseases affecting orofacial region.

Autoimmune diseases are better diagnosed currently with advances in cellular immunology, molecular biology, and genetics. Clinical diagnosis of systemic and organ specific autoimmune diseases is a challenging task for the Oral physicians and the development of chairside investigation methods has not only saved the time but also cost factor. To understand patient's immune status, the clinical chair side diagnostic aids along with laboratory testing methods are necessary.

ANALGESIC EFFECT OF INTRAVENOUS ASCORBIC ACID VERSUS ACELCOFENAC POST-TRANSALVEOLAR EXTRACTION: A CASE-CONTROL STUDY.

One of the most important aspects of postsurgical care is finding an efficient way for the management of pain. Third molar extractions/surgical impaction is one of the most frequent surgical procedures in dental hospitals, and it is most often associated with postoperative complications like severe pain, oedema and reduced mouth opening. This study was aimed to evaluate the efficacy of 2 g intravenous (IV) vitamin C compared to 100 mg aceclofenac on postsurgical pain, swelling and trismus after the surgical removal of third molars.

Laser Excision of Focal Epithelial Hyperplasia (Heck's Disease): A Rare Case Report.

Unlabelled: Heck's disease or focal epithelial hyperplasia is a rare, benign and asymptomatic lesion of oral mucosa that is characterized by the presence of soft, sessile papules, white to pinkish in colour that occur diffusely in oral cavity. Prevalence rate of this disease greatly varies from one geographic region to another. It is found to be closely associated with human papilloma virus (HPV).