1,034 results match your criteria: "Pancreatic Divisum"

Rationale: This case report aims to enhance understanding of pancreatobiliary maljunction (PBM) and promote more proactive treatment.

Patient Concerns: The patient, a 24-year-old Chinese female, was admitted to the hospital on April 7, 2020, due to "recurrent abdominal pain for over 2 years, with a recent episode accompanied by nausea and vomiting for 1 day." She had a previous history of gallstones.

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Acute pancreatitis in children in Japan is often caused by an anatomical abnormality of the pancreatic and bile duct, resulting in fever, abdominal pain, vomiting, diarrhea, and other symptoms. Crohn's disease, however, is a chronic granulomatous inflammatory bowel disease with ulcerative lesions of the intestinal tract of unknown cause that occurs mainly in young people, with symptoms similar to those of acute pancreatitis. We report a case of acute pancreatitis diagnosed in a patient not only with incomplete fusion of the pancreatic duct but also with Crohn's disease.

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Endoscopic Retrograde Cholangiopancreatography: Pancreatic Endoscopy.

Gastroenterol Clin North Am

December 2024

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Article Synopsis
  • - The role of pancreatic endoscopic retrograde cholangiopancreatography (ERCP) has shifted from primarily diagnosing issues to being mainly used for therapeutic treatments, especially for conditions like pancreatitis.
  • - ERCP is particularly effective in treating pancreatic duct (PD) problems, such as leaks, disruptions, strictures, and stone removals.
  • - Advances in pancreatoscopy enhance ERCP's effectiveness by enabling precise treatment of conditions and aiding in the identification and surgical planning for pancreatic tumors.
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Article Synopsis
  • Pancreas divisum (PD) is a common birth defect of the pancreas, but the genetic factors behind it are still unclear, prompting a genome-wide study to find potential genetic links.
  • Researchers analyzed data from 13,940 participants, identifying a significant genetic locus on chromosome 3q29 associated with PD, specifically linked to two genes related to cellular functions.
  • The study not only established a genetic link to PD but also identified potential regulatory genes that might influence pancreatic development, which could aid in better understanding and treating related pancreatic conditions.
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  • A choledochal cyst (CC) and pancreas divisum (PD) are rare abnormalities in the biliary and pancreatic duct systems that can make surgical treatment difficult; this report discusses a 23-year-old woman with both conditions who underwent pancreaticoduodenectomy.* -
  • The patient experienced severe abdominal pain and was initially diagnosed with pancreatitis, leading to the discovery of the choledochal cyst and pancreas divisum through imaging and ERCP.* -
  • The findings suggest that while pancreaticoduodenectomy was performed, this approach may not yield the best outcomes for patients with both CC and PD, as less invasive surgical options might be more effective in managing these conditions.*
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Article Synopsis
  • - Groove pancreatitis (GP) is a rare type of chronic pancreatitis primarily affecting middle-aged men, with risk factors including excessive alcohol use, smoking, and pancreatic issues, leading to symptoms like severe abdominal pain and jaundice.
  • - Diagnosing GP is difficult due to its symptoms overlapping with other conditions, which can result in delayed treatment and increased health risks.
  • - The potential use of artificial intelligence in diagnostic imaging could help differentiate GP from pancreatic cancers, improving diagnosis and patient outcomes, as discussed in a comprehensive review of GP's causes, symptoms, and treatment options.
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Management of Multiple Ducts at the Transected Pancreatic Neck in a Whipple Procedure.

Am Surg

June 2024

Vice Chair of Surgical Education, Director of Surgical Oncology, Program Director for the General Surgery Residency, Department of Surgery, The University of Texas Health Northeast, Tyler, TX, USA.

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In clinical cases of pancreas divisum, endoscopic retrograde cholangiopancreatography often necessitates cannulation of the pancreatic duct through the minor papilla. Nevertheless, this procedure can be challenging because of the small size of the minor papilla and the difficulty in visualizing the ductal orifice. A new image-enhanced endoscopy technique called texture and color enhancement imaging (TXI) has been developed, which enhances texture, brightness, and color compared with white-light imaging, resulting in subtle differences in the surface mucosa.

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Wirsung duct duplication is a very rare condition that can lead to chronic pancreatitis.

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Article Synopsis
  • Pancreas divisum (PD) is a birth defect of the pancreas linked to pancreatitis, and this study examines endoscopic treatment success in patients with symptoms like recurrent acute pancreatitis and chronic abdominal pain.
  • The researchers analyzed data from 27 studies and found that endoscopic intervention had a high technical success rate of 92%, but a lower clinical success rate of 65%, with the best results in patients with recurrent acute pancreatitis.
  • However, there is a notable risk of complications, with adverse event rates reaching 71%, indicating that while endoscopic therapy can be effective, it also carries significant risks.
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Unlooping the meandering main pancreatic duct in chronic pancreatitis.

Gastrointest Endosc

August 2024

National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.

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Objectives: Pancreatic divisum (PD) is the second most common congenital abnormality of the pancreatic duct, which affects 2% to 3% of the population. Most of the population remains asymptomatic, but in people who present with symptoms, it can be a cause of anguish and should be recognized. The main goal of this article was to provide a comprehensive picture of clinical and epidemiological methods of diagnosis and treatment of PD.

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Article Synopsis
  • * A 28-year-old patient with a history of chronic alcoholism experienced recurrent acute pancreatitis that progressed to chronic pancreatitis, which was linked to pancreatic divisum and the presence of pancreatic stones.
  • * The patient was successfully treated using endoscopic techniques, including lithotripsy and stent placement, demonstrating the complicated relationship between ongoing alcohol use and congenital pancreatic conditions in causing pancreatitis.
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  • The study focuses on the usage of endoscopic retrograde cholangiopancreatography (ERCP) in pediatric patients in India, analyzing data from January 2017 to December 2022.
  • A total of 150 pediatric patients were identified, with common conditions being chronic pancreatitis and choledocholithiasis, reporting high technical success rates of 94.3% for pancreatic cases and 95.2% for biliary cases.
  • The research concludes that ERCP is a safe and effective procedure for children, although complications like acute pancreatitis can occur, primarily in the context of pancreatic ERCP.
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Article Synopsis
  • A 56-year-old woman was hospitalized with epigastric pain, and tests indicated she had acute pancreatitis.
  • Imaging revealed a condition called pancreas divisum and a stone located in the minor papilla, which likely caused the pancreatitis.
  • Treatment involved conservative care, and her condition improved, culminating in the spontaneous expulsion of the stone within 10 days, marking a rare case of pancreatitis linked to this anatomical variation.
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In recent years, we have witnessed an evolving landscape in the management of chronic pancreatitis (CP). Endoscopy plays a pivotal role in CP management. Because the management of CP is problematic, we aimed to review and evaluate the role of endoscopy in the management of CP.

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Metastasis to the gastrointestinal (GI) tract should always be a consideration when melanoma, particularly metastatic disease, is diagnosed. While metastasis to the small intestine is common, given its rich blood supply, metastasis to the pancreatic ducts is extremely rare. In patients with pancreatic divisum, disease spread to the minor papilla can greatly increase the chance of developing pancreatitis due to the potential for increased pancreatic intraductal pressure.

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