1 results match your criteria: "Pancreatic Disease Research Center of Shanghai[Affiliation]"
Bioinformatics analysis of transcription profiling of solid pseudopapillary neoplasm of the pancreas.
Mol Med Rep
August 2017
Digestive Department, Hangzhou First People's Hospital, Pancreatic Disease Research Center of Shanghai, Hangzhou, Zhejiang 310006, P.R. China.
Article Synopsis
- Solid pseudopapillary neoplasm (SPN) is a rare, low-grade malignant pancreatic tumor, making up about 5% of cystic pancreatic tumors.
- Researchers analyzed transcription data from 14 SPN and 6 control samples to identify differentially expressed genes (DEGs), resulting in 710 upregulated and 710 downregulated genes, including key tumor-associated genes.
- Protein-protein interaction (PPI) network analysis highlighted hub genes like EGFR and MYC, suggesting that they, along with the ErbB and GnRH signaling pathways, play crucial roles in the progression of SPN.