461 results match your criteria: "Pancreas Divisum Imaging"

Endoscopic Retrograde Cholangiopancreatography: Pancreatic Endoscopy.

Gastroenterol Clin North Am

December 2024

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Article Synopsis
  • - The role of pancreatic endoscopic retrograde cholangiopancreatography (ERCP) has shifted from primarily diagnosing issues to being mainly used for therapeutic treatments, especially for conditions like pancreatitis.
  • - ERCP is particularly effective in treating pancreatic duct (PD) problems, such as leaks, disruptions, strictures, and stone removals.
  • - Advances in pancreatoscopy enhance ERCP's effectiveness by enabling precise treatment of conditions and aiding in the identification and surgical planning for pancreatic tumors.
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Article Synopsis
  • Pancreas divisum (PD) is a common birth defect of the pancreas, but the genetic factors behind it are still unclear, prompting a genome-wide study to find potential genetic links.
  • Researchers analyzed data from 13,940 participants, identifying a significant genetic locus on chromosome 3q29 associated with PD, specifically linked to two genes related to cellular functions.
  • The study not only established a genetic link to PD but also identified potential regulatory genes that might influence pancreatic development, which could aid in better understanding and treating related pancreatic conditions.
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Article Synopsis
  • A choledochal cyst (CC) and pancreas divisum (PD) are rare abnormalities in the biliary and pancreatic duct systems that can make surgical treatment difficult; this report discusses a 23-year-old woman with both conditions who underwent pancreaticoduodenectomy.* -
  • The patient experienced severe abdominal pain and was initially diagnosed with pancreatitis, leading to the discovery of the choledochal cyst and pancreas divisum through imaging and ERCP.* -
  • The findings suggest that while pancreaticoduodenectomy was performed, this approach may not yield the best outcomes for patients with both CC and PD, as less invasive surgical options might be more effective in managing these conditions.*
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Article Synopsis
  • - Groove pancreatitis (GP) is a rare type of chronic pancreatitis primarily affecting middle-aged men, with risk factors including excessive alcohol use, smoking, and pancreatic issues, leading to symptoms like severe abdominal pain and jaundice.
  • - Diagnosing GP is difficult due to its symptoms overlapping with other conditions, which can result in delayed treatment and increased health risks.
  • - The potential use of artificial intelligence in diagnostic imaging could help differentiate GP from pancreatic cancers, improving diagnosis and patient outcomes, as discussed in a comprehensive review of GP's causes, symptoms, and treatment options.
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In clinical cases of pancreas divisum, endoscopic retrograde cholangiopancreatography often necessitates cannulation of the pancreatic duct through the minor papilla. Nevertheless, this procedure can be challenging because of the small size of the minor papilla and the difficulty in visualizing the ductal orifice. A new image-enhanced endoscopy technique called texture and color enhancement imaging (TXI) has been developed, which enhances texture, brightness, and color compared with white-light imaging, resulting in subtle differences in the surface mucosa.

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Unlooping the meandering main pancreatic duct in chronic pancreatitis.

Gastrointest Endosc

August 2024

National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, China.

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Article Synopsis
  • A 56-year-old woman was hospitalized with epigastric pain, and tests indicated she had acute pancreatitis.
  • Imaging revealed a condition called pancreas divisum and a stone located in the minor papilla, which likely caused the pancreatitis.
  • Treatment involved conservative care, and her condition improved, culminating in the spontaneous expulsion of the stone within 10 days, marking a rare case of pancreatitis linked to this anatomical variation.
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Article Synopsis
  • Endoscopic ultrasound (EUS) is a vital tool in gastroenterology, used for diagnosing and assessing various pancreatic conditions with advanced imaging techniques and interventional capabilities.
  • The review emphasizes EUS's role in identifying normal anatomical variations and pancreatic masses, facilitating accurate diagnoses that are crucial for both malignant and benign conditions.
  • Recent advancements in computer-aided diagnosis and artificial intelligence may enhance EUS's effectiveness by reducing variability in interpretations and improving decision-making in managing pancreatic diseases.
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Endoscopic Ultrasound in Pancreatic Duct Anomalies.

Diagnostics (Basel)

October 2023

Department of Gastroenterology, Post Graduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh 160012, India.

Embryological development of the pancreas is a complex phenomenon and, therefore, it can have multiple developmental aberrations. Fortunately, the majority of these pancreatic ductal anomalies are asymptomatic with no clinical relevance and are incidentally detected during diagnostic cross-sectional imaging or endoscopic retrograde cholangiopancreatography (ERCP) or autopsy. Occasionally, pancreatic duct anomalies can result in symptoms like abdominal pain or recurrent pancreatitis.

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Article Synopsis
  • - Environmental risk factors for pancreatic cancer include conditions like pancreatitis, obesity, and tobacco use, which complicate diagnosis due to overlapping symptoms.
  • - A 57-year-old man with a history of pancreatitis and heart failure experienced severe abdominal pain, and imaging revealed complicated necrotizing pancreatitis along with a mass in the pancreas tail.
  • - After being discharged, he was readmitted with ongoing pain, and further imaging confirmed the mass as locally advanced pancreatic adenocarcinoma, emphasizing the link between chronic pancreatitis and pancreatic cancer.
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A 50-year old male with acute necrotizing pancreatitis had an unfavorable evolution in the third week of disease, with development of large volume ascites and walled-off necrosis affecting the head and body of pancreas, suspected to be infected, with viable parenchyma in the tail of pancreas. Endoscopic ultrasound guided drainage of the collection was performed through placement of a lumen apposing metal stent. Selective cannulation of main pancreatic duct was only possible though the minor papilla and after contrast media injection a type 1 pancreas divisum and partial disruption of dorsal pancreatic duct were diagnosed.

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Key Clinical Message: Pancreas divisum (PD) can be one of the causes of unexplained chronic abdominal pain. In PD, the dominant duct drains the majority of the pancreas via the minor papilla, which can be conveyed in the imaging as crossing duct sign.

Abstract: We report a case a of 16-year-old man who presented with unexplained chronic abdominal pain.

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Agenesis of the dorsal pancreas is a rare congenital disorder with only a handful of cases described in the literature. It presents a diagnostic dilemma. Cross-sectional imaging is the cornerstone for diagnosis.

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