3,805 results match your criteria: "Pamukkale University.[Affiliation]"
The Effect of Boric Acid and Calcium Fructoborate on T Helper Cell Differentiation by Influencing Foxp3 and Ror-γt in Rheumatoid Arthritis and Systemic Lupus Erythematosus.
Biol Trace Elem Res
October 2024
Department of Medical Biology, Faculty of Medicine, Manisa Celal Bayar University, Manisa, Turkey.
Article Synopsis
- The study explores how boric acid and calcium fructoborate impact immune system cells, specifically Treg and Th17 cell populations, in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
- It involved blood samples from newly diagnosed RA and SLE patients and healthy individuals, exposing isolated mononuclear cells to varying doses of boric acid and calcium fructoborate to analyze effects on cell populations and cytokine levels.
- Results indicated that while high-dose boric acid improved Treg/Th17 ratios in healthy controls, it did not have the same effect in RA and SLE patients; however, both boron compounds showed a potential positive impact on inflammation markers in RA.
Investigation of Physical Fitness in Children and Adolescents with Juvenile Idiopathic Arthritis: A Case-Control Study.
Turk Arch Pediatr
September 2024
Department of Pediatric Rheumatology, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Türkiye.
Swelling, effusion, tenderness, and pain seen in the joints of juvenile idiopathic arthritis (JIA). This disease may cause limitation in joint movements, muscle weakness, atrophy, balance, and gait disorders. Physical fitness is accepted as an important determinant of health in both childhood and adolescence.
View Article and Find Full Text PDFThis study evaluates the reliability and validity of the Turkish version of the Work-Related Stress Scale (WRSS) among search and rescue workers who responded to the 2023 KahramanmaraÅŸ earthquakes. Data were collected from 275 workers between January and April 2024 using the Personal Information Form and the Turkish version of the WRSS. Language, content, and construct validity were assessed, and reliability was determined using item-total correlation, Cronbach's alpha, split-half, and test-retest methods.
View Article and Find Full Text PDFBridging the knowledge gap-microplastics in focus: assessing microplastic pollution awareness among medical students.
Int J Environ Health Res
October 2024
Department of Public Health, Medical Faculty, Pamukkale University, Denizli, Türkiye.
Microplastic pollution is a growing environmental and health issue. This study evaluates microplastic pollution awareness among medical students at Pamukkale University and the factors influencing it. A cross-sectional study was conducted in June 2023 with 474 students from the 1st, 3rd, and 6th years, using a 26-item questionnaire, including the 14-item Microplastic Pollution Awareness Scale (MPAS).
View Article and Find Full Text PDFPrediction of complications after laparoscopic partial nephrectomy: feasibility of E‑PASS score.
Int Urol Nephrol
October 2024
Department of Urology, Pamukkale University Hospital, Denizli, Turkey.
Purpose: With significant advancements in laparoscopic procedures and tools over the last decade, the partial nephrectomy (PN) surgical approach has gradually transformed from open to laparoscopic partial nephrectomy (LPN). Although numerous studies evaluating the postoperative complications of laparoscopic partial nephrectomy can be found in the literature, a scoring system that addresses both preoperative physical condition and intraoperative risk factors has not yet been established. The Estimation of Physiological Ability and Surgical Stress (E-PASS) score is a scoring system that considers both the patient's preoperative condition and intraoperative variables to predict the risk of postoperative complications in surgically treated patients.
View Article and Find Full Text PDFPatients with crush syndrome and kidney disease: lessons learned from the earthquake in Kahramanmaraş, Türkiye.
Kidney Int
November 2024
Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Istanbul University, Istanbul, Türkiye.
Article Synopsis
- * About 9.8% of the patients died during hospitalization, with older individuals and those with preexisting kidney issues showing higher mortality rates due to severe injuries and complications.
- * Key factors influencing mortality included age, injury severity, shock, and certain elevated lab values, highlighting the need for better disaster preparedness and health care improvements for future events.
The validity of Turkish version of Social Frailty Index in older adults: An index of social attributes predictive of mortality.
Rev Esp Geriatr Gerontol
October 2024
Faculty of Physiotherapy and Rehabilitation, Pamukkale University, Denizli, Turkey.
Purpose: The aim of this study was to examine the validity of Turkish version of Social Frailty Index in older adults.
Material And Methods: 102 older adults aged 65 and over were included in the study. Hodkinson Mental Test was first applied to older adults.
Prevalence of Cardiovascular Disease and Comparison of Risk Category Predictions of Systemic Coronary Risk Evaluation Score-2 and 4 Other Cardiovascular Disease Risk Assessment Tools Among People Living with Human Immunodefficiency Virus in Türkiye.
Anatol J Cardiol
October 2024
Department of Infectious Diseases and Clinical Microbiology, Marmara University Hospital, İstanbul, Türkiye.
Article Synopsis
- Cardiovascular disease (CVD) significantly affects people living with HIV (PLWH), with this study finding a diagnosed CVD prevalence of 10.8% among 1425 participants aged 40-75.
- The assessment utilized five different risk evaluation tools, revealing that 42.8% of participants had a high 10-year risk of CVD, while 71.7% were classified as high- to very high-risk using the SCORE2 tool.
- The findings stress the need for better cardiovascular health monitoring and highlighted that current utilization of lipid-lowering therapy is inadequate, despite a large number of PLWH being eligible for such treatment per recent guidelines.
Human anti-apoptotic Bcl-2 and Bcl-xL proteins protect yeast cells from aging induced oxidative stress.
Biochimie
October 2024
Department of Biology, Faculty of Science, Ataturk University, Erzurum, Turkey; East Anatolian High Technology Research and Application Center, Ataturk University, Erzurum, Turkey.
Article Synopsis
- * Research revealed that human anti-apoptotic proteins Bcl-2 and Bcl-xL have strong anti-aging effects in yeast, enhancing reproductive survival and protecting against aging-related damage.
- * Specifically, Bcl-xL was found to boost antioxidant enzyme activity at a critical stage of the yeast lifespan, suggesting that understanding its function in yeast could improve our knowledge of similar processes in more complex organisms.
Artificial Intelligence Applications for Imaging Metabolic Bone Diseases.
Semin Musculoskelet Radiol
October 2024
Dipartimento di Scienze Mediche e Chirurgiche, Bologna University, Bologna, Italy.
Article Synopsis
- AI is revolutionizing medical imaging for metabolic bone diseases (MBDs) like osteoporosis and rare conditions, enhancing diagnosis and management.
- The article analyzes various AI techniques, recent advancements, and their clinical applications, while addressing ethical issues and future developments.
- By combining AI with existing imaging methods, there is potential for improved diagnostic accuracy and patient outcomes in the treatment of MBDs.
Online Parenting Programs for Children's Behavioral and Emotional Problems: a Network Meta-Analysis.
Prev Sci
October 2024
University of Amsterdam, Amsterdam, Netherlands.
Article Synopsis
- Online parenting programs designed to help parents of children with behavioral and emotional issues have been shown to positively impact child development, parenting practices, and parental mental health.
- This study aims to fill the gap in understanding which online content is most effective by analyzing data from 27 randomized controlled trials involving over 5,300 participants.
- Results indicate that online programs based on learning theory, especially those that include parental self-care and therapeutic approaches, are particularly effective in improving children's behavioral and emotional problems.
Evaluation of neuropathy in epidermal growth factor administered patients diagnosed with diabetic foot.
J Tissue Viability
November 2024
Aydın Adnan Menderes University Faculty of Nursing, Aydın, Turkey. Electronic address:
Article Synopsis
- This study aimed to assess the effects of epidermal growth factor (EGF) on neuropathy in diabetic foot patients, along with its influence on foot ulcers and neuropathic pain.
- Conducted with 30 patients at Pamukkale University Hospitals between March 2021 and November 2022, the study used a single-group pretest-posttest design to collect data before and after EGF treatment, analyzing results through various statistical tests.
- Findings revealed that while 100% of participants had neuropathy initially, this reduced to 56.7% post-treatment, indicating significant improvements in neuropathy symptoms and overall health metrics like HbA1c levels and pain scores (SINBAD and LANSS).
Evaluation of average penis length and the thoughts of Turkish men and partners. Is surgery necessary?
Rev Int Androl
September 2024
UroCentre Urology Clinic, 01060 Adana, Turkey.
Article Synopsis
- A study was conducted with 1703 males and 139 female partners in Turkey to measure average penis size and evaluate couples' perspectives on its importance for sexual satisfaction.
- The findings showed that the average flaccid penis length was 8.44 cm and the average stretched length was 12.27 cm, with girth measuring 8.23 cm; both males and females considered erect length and girth important for sexual pleasure.
- Despite the participants' beliefs about the significance of penis size, comparisons indicated no major difference between average measurements and ideal lengths, suggesting many men may not need surgery to meet perceived standards.
Biopsychosocial conditions of patients in the rheumatology department of a university hospital.
Reumatologia
August 2024
Department of Rheumatology, Medical Faculty, Pamukkale University, Denizli, Turkey.
Introduction: The aim was to examine biopsychosocial conditions of patients hospitalized in the rheumatology department of a university hospital.
Material And Methods: Ninety-six patients (mean age: 53.14 ±16.
Effects of telerehabilitation-implemented core stability exercises on patient-reported and performance-based outcomes in total knee arthroplasty patients: randomised controlled trial.
Physiother Theory Pract
October 2024
Pamukkale University Faculty of Physiotherapy and Rehabilitation Physiotherapy and Rehabilitation Department, Denizli, Turkey.
Article Synopsis
- - The study aimed to assess the impact of adding core stability exercises (CSE) to standard exercises (SE) in total knee arthroplasty (TKA) patients using telerehabilitation (TR) to improve outcomes.
- - Two groups were compared: one received only SE, and the other received both SE and CSE, with various assessments conducted before and after surgery to evaluate functioning, pain, range of motion, strength, and quality of life.
- - Results showed that both groups improved significantly, but the SE+CSE group had greater benefits in function, pain relief, knee extension, quality of life, muscle strength, and overall performance, suggesting the value of incorporating CSE into TR programs for TKA patients
Investigation of Herbal Therapy Methods Used by Parents of Children with Cancer for Symptom Management in Chemotherapy Process.
Complement Med Res
December 2024
Department of Nursing, Health Science Faculty, Mehmetbey University, Karaman, Turkey.
Article Synopsis
- The study aimed to explore the use of herbal treatments by parents of children with cancer during chemotherapy to manage symptoms, highlighting an increasing trend in childhood cancer cases.
- Researchers collected data from 126 parents through a questionnaire about their herbal treatment methods, finding that a significant majority—78.6%—reported using such treatments, believing them to be effective.
- Results indicated that the use of herbal remedies was influenced by factors such as the mother's profession, parents' education levels, and their place of residence, suggesting a need for better education for parents on this topic from healthcare professionals.
Exploring the impact of sexual positions on ejaculation: Insights from a survey study by the Andrology Working Group of the Society of Urological Surgery in Turkey.
Andrology
October 2024
Department of Urology, EPC Hospital, Adana, Turkey.
Article Synopsis
- The study explores how different sexual positions impact ejaculation duration and the overall control of ejaculation, which is important for sexual pleasure.
- Conducted through an online survey with 1904 heterosexual men aged 18-65, it looked at factors related to premature ejaculation (PE) and how these men engage in various sexual positions.
- Results indicated a significant preference for doggy style across all groups, with non-PE participants more likely to change positions when close to ejaculation compared to PE participants, suggesting that adjusting sexual positions may help manage PE.
A YOLO-V5 approach for the evaluation of normal fillings and overhanging fillings: an artificial intelligence study.
Braz Oral Res
October 2024
Eskisehir Osmangazi University, Faculty of Dentistry, Department of Oral and Maxillofacial Radiology, Eskişehir, Türkiye.
Dental fillings, frequently used in dentistry to address various dental tissue issues, may pose problems when not aligned with the anatomical contours and physiology of dental and periodontal tissues. Our study aims to detect the prevalence and distribution of normal and overhanging filling restorations using a deep CNN architecture trained through supervised learning, on panoramic radiography images. A total of 10480 fillings and 2491 overhanging fillings were labeled using CranioCatch software from 2473 and 1850 images, respectively.
View Article and Find Full Text PDFHead and Neck Paragangliomas: 16-year Single-center Experience and Mini Review on Diagnosis, Treatment, and Follow-up.
Medeni Med J
September 2024
Pamukkale University Faculty of Medicine, Department of Medical Pathology, Denizli, Türkiye.
Objective: To investigate head and neck paraganglioma cases treated at a tertiary center from 2007 to 2023. The research includes a thorough examination of published studies that have focused on long-term outcomes. The additional goal is to contribute to the existing knowledge on head and neck paraganglioma, with a particular emphasis on refining diagnostic algorithms, treatment selection, and follow-up procedures.
View Article and Find Full Text PDFHyperchloremia and Prolonged Acidosis During Treatment for Pediatric Diabetic Ketoacidosis.
Pediatr Emerg Care
December 2024
From the Department of Pediatric Endocrinology, Pamukkale University, Denizli, Turkey.
Article Synopsis
- Diabetic ketoacidosis (DKA) can lead to hyperchloremic metabolic acidosis (HMA) due to chloride overload from intravenous hydration, which may prolong acidosis even after ketonemia resolves.
- In a study of 178 DKA episodes, hyperchloremia was found in 69.3% of patients, developing about 6.3 hours into treatment, with severity increasing over time.
- Monitoring additional parameters like anion gap and chloride-corrected bicarbonate can help distinguish DKA from HMA, potentially reducing the duration of intravenous treatment.
Expression Profiles of Claudin Gene Family Members in Patients With Recurrent Calcium Oxalate Kidney Stones.
Cureus
September 2024
Department of Urology, School of Medicine, Pamukkale University, Denizli, TUR.
Article Synopsis
- This study investigated gene expression related to stone formation in patients with recurrent calcium oxalate stones compared to individuals without a history of renal stones.
- Nineteen patients with recurrent stones and 21 control patients were analyzed, with normal biochemical parameters and no significant urinary abnormalities noted.
- Results showed that the gene expression related to stone formation was significantly higher in the stone-forming group, suggesting that this overexpression may contribute to the development of recurrent calcium oxalate stones.
Changes in Testosterone Levels Following Surgical Sperm Retrieval in Men with Non-Obstructive Azoospermia: Systematic Review and Meta-Analysis.
World J Mens Health
September 2024
Global Andrology Forum, Moreland Hills, OH, USA.
Article Synopsis
- Surgical sperm retrieval (SSR) is performed to extract sperm from men with azoospermia and may result in reduced testosterone levels and other hormonal changes post-operation.* -
- A systematic review analyzed 17 studies involving 1,685 azoospermic men, revealing a significant decrease in testosterone after SSR, but no major changes in follicle-stimulating hormone (FSH), luteinizing hormone (LH), or testicular volume.* -
- The study highlights the importance of considering potential sexual dysfunction and the psychosocial impacts of SSR in postoperative care and preoperative discussions.*
Bimodal functionality of highly conductive nanostructured silver film towards improved performance of photosystem I-based graphene photocathode.
Bioelectrochemistry
February 2025
Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Torun, GrudziÄ…dzka 5, 87-100 Torun, Poland. Electronic address:
Article Synopsis
- A new design for biosolar cells using photosystem I (PSI) replaces traditional transparent conductive materials with a glass substrate coated in a silver island film.
- This metallic layer improves both electric conductivity and the absorption efficiency of PSI through the plasmonic effect.
- The study shows that the interaction between PSI components and the silver film significantly boosts the photocurrent in the biohybrid electrode, indicating enhanced solar energy conversion.
Effectiveness of Mulligan Mobilization Technique and Core Stabilization Exercises in Female Patients With Knee Osteoarthritis: A Randomized Controlled Single-Blind Study.
J Manipulative Physiol Ther
December 2024
Hakkari Public Hospital, Physical Medicine and Rehabilitation, Hakkari, Turkey.
Objectives: The aim of this study was to compare the effectiveness of the Mulligan mobilization (MM) technique and Core stabilization (CS) exercises added to the conventional physiotherapy (CP) program in female patients with knee osteoarthritis (KOA).
Methods: The study included 42 female patients diagnosed with bilateral KOA. Participants were randomly divided into 3 groups as CP group (mean age: 57.
Age and Body Size of the Endemic and Critically Endangered Frog Species (Baran and Atatür, 1986) in Türkiye.
Animals (Basel)
September 2024
Department of Biology, Faculty of Science, Karadeniz Technical University, 61080 Trabzon, Turkey.
This study used skeletochronology to assess the relationships between age and body length among individuals in a population of the Tavas Frog (), located in the Çakıroluk plateau, Tavas district, Denizli province. The age varied from 3 to 12 years in both adult males and females. The age was 2 years in two subadult males, while it was 1 year in one juvenile specimen.
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