Enhancement of kefir functionality by adding black elderberry and evaluation of its quality during storage.

The research explored the influences of 2% and 4% heat-treated fresh elderberry fruit mash supplement and 0.5% and 1% dried elderberry powder supplement before and after fermentation in kefir production on certain features of kefir beverage. Antioxidant activity, total monomeric anthocyanin, and total phenolic content were 16.

Effects of blood transfusion, cardiopulmonary bypass time, and bypassed vessels on mortality following isolated and combined coronary artery bypass grafting.

Objective: This study aimed to investigate the correlation between the number of bypassed vessels, the duration of Cardiopulmonary bypass, blood transfusion requirements, revision rates, and mortality outcomes. The objective was to get insights into the potential challenges that may arise during the postoperative phase.

Methods: Our study covered a total of 677 patients from January 2015 to January 2021.

Medical faculty students risk perception, attitudes, and behaviors regarding protection from COVID-19 infection.

Objective: This study aims to determine the risk perception, attitude, and behavior characteristics of Pamukkale University Faculty of Medicine students towards protection from COVID-19.

Subjects And Methods: A total of 698 (48.2%) students of Pamukkale University Faculty of Medicine participated in this analytical cross-sectional study.

Biochemical, pharmacological, and toxicological attributes of caper () flowering buds and berries pickles.

is a natural plant that grows widely in Turkey and its flowering buds and berry pickle are used in traditional medicine. Thus, the current study was expanded to evaluate the biochemical, pharmacological, and toxicological aspects of the water extract (COWE). To determine the biochemical properties of COWE, mineral and fatty acid content, elemental analysis, flavonoid/phenolic content, radical-scavenging capacity, and pesticide analysis were performed.

Relationship between embryo development and apoptotic gene expression of cumulus cells in poor responders and polycystic ovary syndrome.

Research Question: Is there a relationship between embryo quality, pregnancy rates and apoptotic gene expression in cumulus cells of oocytes collected from patients with poor ovarian response and polycystic ovary syndrome?

Design: Fifty infertile couples who underwent assisted reproductive technology treatment were included in the study (Approval date 4 February 2020, number 03). The patients were divided into four group: control (n = 9; 90 oocytes), unexplained infertility (n = 8; 86 oocytes), polycystic ovary syndrome (PCOS) (n = 6; 137 oocytes) and poor ovarian response (POR) (n = 27; 124 oocytes). Cumulus cells were isolated individually from 437 oocytes obtained.

The effectiveness and safety of ibuprofen and acetylsalicylic acid in acute rheumatic fever.

Background: Acetylsalicylic acid (ASA) is a non-steroidal anti-inflammatory drug used in the treatment of acute rheumatic fever (ARF) and it can cause serious adverse effects. This study aimed to evaluate the clinical efficacy and side effects of ibuprofen in the treatment of ARF compared to the classic treatment, ASA.

Methods: Children who were hospitalized for the treatment of ARF with isolated arthritis and mild carditis between October 2015 and October 2018 and who received non-steroidal anti-inflammatory therapy were evaluated in the study.

The impact of quinoa flour on some properties of ayran.

In this study, some physical, chemical, microbiological, and sensory properties of ayran produced from quinoa flour addition at different ratios (0.1, 0.2, 0.

Evaluation of ivabradine in left ventricular dyssynchrony and reverse remodeling in patients with chronic heart failure.

Objectives: Ivabradine is a pharmacological agent used in patients with heart failure and sinus rhythm. Its only known pharmacological effect is to slow the heart rate. In this study, we investigated the impact of ivabradine on dyssynchrony parameters in heart failure patients.

Interval Versus Continuous Aerobic Exercise Training in Overweight and Obese Patients With Chronic Obstructive Pulmonary Disease: A RANDOMIZED CONTROLLED STUDY.

Purpose: The aim of this study was to compare the efficacy of the supervised pulmonary rehabilitation programs consisting of either an interval or continuous aerobic exercise program, with a home-based exercise program in patients with chronic obstructive pulmonary disease (COPD) who were overweight or obese.

Methods: In this randomized controlled study, 72 overweight and obese patients diagnosed as having COPD were randomly assigned to 3 groups. Group 1 received an interval-type (IT) aerobic exercise program, group 2 received a continuous-type (CT) aerobic exercise program (both groups performed home exercises as well) and group 3 was only given a home-based exercise (HE) program.

Serum vitamin D in patients with mild cognitive impairment and Alzheimer's disease.

Objectives: To determine the relevance of Mini-Mental State Examination (MMSE), serum 25-hydroxyvitamin D (25(OH)D3), and 1,25(OH)2D3 concentrations to mild cognitive impairment (MCI) and various stages of Alzheimer's disease (AD).

Materials And Methods: The study included 230 participants (>74 years) allocated to three main groups: 1-healthy subjects (HS,  = 61), 2-patients with MCI ( = 61), and 3- patients with Alzheimer's disease (AD) subdivided into three stages: mild ( = 41), moderate ( = 35), and severe AD ( = 32). The cognitive status was evaluated using MMSE.

Solid Phase Extraction Preconcentration Method for Simultaneous Determination of Cadmium, Lead, and Nickel in Poultry Supplements.

A new simple, selective, and economical preconcentration method was developed for the determination of Cd, Pb, and Ni in poultry antibiotics and supplements. The proposed preconcentration procedure is based on SPE using 8-hydroxyquinoline and Amberlite IRC-50 resin as complex and adsorbent, respectively. The determination was carried out by microsample injection system (MIS) flame atomic absorption spectroscopy (FAAS).

Molecular spectrum and differential diagnosis in patients referred with sporadic or autosomal recessive osteogenesis imperfecta.

Background: Osteogenesis imperfecta (OI) is a heterogeneous bone disorder characterized by recurrent fractures. Although most cases of OI have heterozygous mutations in or and show autosomal dominant inheritance, during the last years there has been an explosion in the number of genes responsible for both recessive and dominant forms of this condition. Herein, we have analyzed a cohort of patients with OI, all offspring of unaffected parents, to determine the spectrum of variants accounting for these cases.

Effects of endovenous laser ablation on vascular tissue: molecular genetics approach.

Background: Endovenous laser ablation (EVLA) is a treatment option for lower extremity varicose veins. In the present study, we investigate to the genetic changes and possibility of living tissue in the saphenous vein wall after the EVLA procedure.

Methods: Eleven saphenous vein grafts were randomized in two groups: (1) 4 cm SVG segments of performed EVLA procedure in study group, (2) 4 cm segments of SVG none performed EVLA procedure in control group.

Multidisciplinary clinical management of paroxysmal nocturnal hemoglobinuria.

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired disease caused by clonal expansion of one or more hematopoietic stem cell (HSC) lines due to a somatic mutation of the phosphatidylinositol glycan anchor (PIG-A) gene located on Xp22.1. PNH incidence is 1.

Nursing as career choice: perceptions of Turkish nursing students.

Students' perceptions of nursing influence their choice of nursing as a career and whether they remain in the profession. The aim of this study was to explore the perceptions of entry-level male and female nursing students and the reasons for choosing nursing as a career. A qualitative approach was used by focus group interviews with 31 nursing students, and socio-demographic data were collected by questionnaire.

Musculoskeletal system problems and quality of life of mothers of children with cerebral palsy with different levels of disability.

Objective: The objective of this study is to investigate musculoskeletal system problems and quality of life of mothers of children with cerebral palsy with different levels of disability.

Methods: 100 children (37 girls and 63 boys) with cerebral palsy (CP) and their mothers were included in this study. Functional levels of children with CP were assessed by using the Gross Motor Function Classification System (GMFCS) and the Pediatric Functional Independence Measure (WeeFIM).

Local rhBMP-2 injection after drill-hole injury in rats: does it have systemic effects?

The aim of this study is to investigate the histopathological findings of drill hole healing and interactions of parathyroid hormone (PTH), β-catenin and transcription factor-4 (TCF7L2/Tcf-4) after local application of recombinant human bone morphogenic protein-2 (rhBMP-2). Sprague Dawley rats were used in two groups of ‘femoral cortex hole model’. In the non-treated group, a hole was opened with a 3 mm K-wire in the distal and mid third junction of the right femur.

Decreased Ocular Pulse Amplitude and Retinal Nerve Fibre Layer in Multiple Sclerosis.

This study was conducted to assess ocular pulse amplitude and retinal nerve fibre layer in patients with multiple sclerosis and their correlation with disease duration and with severity. Retinal nerve fibre layer thickness was measured by Heidelberg Retinal Tomography II (HRT-II; Heidelberg Engineering, Dossenheim, Germany) and ocular pulse amplitude was measured by dynamic contour tonometry (Ziemer Ophthalmic Systems, Port, Switzerland) in 37 multiple sclerosis patients and 72 age- and gender-matched controls. Ocular pulse amplitude was significantly reduced and retinal nerve fibre layer was significantly thinner in temporal, superotemporal, and nasal sectors in patients with multiple sclerosis regardless of having an optic neuritis attack.

Evaluation of the applicability of the Clinical Care Classification System to the care of elderly nursing home residents.

The purpose of this study was to translate the Clinical Care Classification System into Turkish and evaluate its applicability to the care of elderly nursing home residents. This study uses a quasi-experimental design in which interventions and evaluations are repeated at specified time intervals in a single group and in which the Clinical Care Classification System is evaluated in a descriptive manner through the use of documents obtained from the system to test the applicability of the system for the care of elderly nursing home residents. Twenty-eight elderly people participated in the study.