4,026 results match your criteria: "Pamukkale University; Faculty of Science; Department of Biology; Denizli; Turkiye. ykatilmis@pau.edu.tr.[Affiliation]"

Article Synopsis
  • - The study aimed to assess the impact of adding core stability exercises (CSE) to standard exercises (SE) in total knee arthroplasty (TKA) patients using telerehabilitation (TR) to improve outcomes.
  • - Two groups were compared: one received only SE, and the other received both SE and CSE, with various assessments conducted before and after surgery to evaluate functioning, pain, range of motion, strength, and quality of life.
  • - Results showed that both groups improved significantly, but the SE+CSE group had greater benefits in function, pain relief, knee extension, quality of life, muscle strength, and overall performance, suggesting the value of incorporating CSE into TR programs for TKA patients
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  • The study aimed to explore the use of herbal treatments by parents of children with cancer during chemotherapy to manage symptoms, highlighting an increasing trend in childhood cancer cases.
  • Researchers collected data from 126 parents through a questionnaire about their herbal treatment methods, finding that a significant majority—78.6%—reported using such treatments, believing them to be effective.
  • Results indicated that the use of herbal remedies was influenced by factors such as the mother's profession, parents' education levels, and their place of residence, suggesting a need for better education for parents on this topic from healthcare professionals.
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  • The study explores how different sexual positions impact ejaculation duration and the overall control of ejaculation, which is important for sexual pleasure.
  • Conducted through an online survey with 1904 heterosexual men aged 18-65, it looked at factors related to premature ejaculation (PE) and how these men engage in various sexual positions.
  • Results indicated a significant preference for doggy style across all groups, with non-PE participants more likely to change positions when close to ejaculation compared to PE participants, suggesting that adjusting sexual positions may help manage PE.
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Dental fillings, frequently used in dentistry to address various dental tissue issues, may pose problems when not aligned with the anatomical contours and physiology of dental and periodontal tissues. Our study aims to detect the prevalence and distribution of normal and overhanging filling restorations using a deep CNN architecture trained through supervised learning, on panoramic radiography images. A total of 10480 fillings and 2491 overhanging fillings were labeled using CranioCatch software from 2473 and 1850 images, respectively.

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Objective: To investigate head and neck paraganglioma cases treated at a tertiary center from 2007 to 2023. The research includes a thorough examination of published studies that have focused on long-term outcomes. The additional goal is to contribute to the existing knowledge on head and neck paraganglioma, with a particular emphasis on refining diagnostic algorithms, treatment selection, and follow-up procedures.

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  • Diabetic ketoacidosis (DKA) can lead to hyperchloremic metabolic acidosis (HMA) due to chloride overload from intravenous hydration, which may prolong acidosis even after ketonemia resolves.
  • In a study of 178 DKA episodes, hyperchloremia was found in 69.3% of patients, developing about 6.3 hours into treatment, with severity increasing over time.
  • Monitoring additional parameters like anion gap and chloride-corrected bicarbonate can help distinguish DKA from HMA, potentially reducing the duration of intravenous treatment.
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  • This study investigated gene expression related to stone formation in patients with recurrent calcium oxalate stones compared to individuals without a history of renal stones.
  • Nineteen patients with recurrent stones and 21 control patients were analyzed, with normal biochemical parameters and no significant urinary abnormalities noted.
  • Results showed that the gene expression related to stone formation was significantly higher in the stone-forming group, suggesting that this overexpression may contribute to the development of recurrent calcium oxalate stones.
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  • Surgical sperm retrieval (SSR) is performed to extract sperm from men with azoospermia and may result in reduced testosterone levels and other hormonal changes post-operation.* -
  • A systematic review analyzed 17 studies involving 1,685 azoospermic men, revealing a significant decrease in testosterone after SSR, but no major changes in follicle-stimulating hormone (FSH), luteinizing hormone (LH), or testicular volume.* -
  • The study highlights the importance of considering potential sexual dysfunction and the psychosocial impacts of SSR in postoperative care and preoperative discussions.*
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  • A new design for biosolar cells using photosystem I (PSI) replaces traditional transparent conductive materials with a glass substrate coated in a silver island film.
  • This metallic layer improves both electric conductivity and the absorption efficiency of PSI through the plasmonic effect.
  • The study shows that the interaction between PSI components and the silver film significantly boosts the photocurrent in the biohybrid electrode, indicating enhanced solar energy conversion.
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Objectives: The aim of this study was to compare the effectiveness of the Mulligan mobilization (MM) technique and Core stabilization (CS) exercises added to the conventional physiotherapy (CP) program in female patients with knee osteoarthritis (KOA).

Methods: The study included 42 female patients diagnosed with bilateral KOA. Participants were randomly divided into 3 groups as CP group (mean age: 57.

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This study used skeletochronology to assess the relationships between age and body length among individuals in a population of the Tavas Frog (), located in the Çakıroluk plateau, Tavas district, Denizli province. The age varied from 3 to 12 years in both adult males and females. The age was 2 years in two subadult males, while it was 1 year in one juvenile specimen.

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Effect of adequacy of empirical antibiotic therapy for hospital-acquired bloodstream infections on intensive care unit patient prognosis: a causal inference approach using data from the Eurobact2 study.

Clin Microbiol Infect

December 2024

OUTCOMEREA Research Group, Drancy, France; Institut National de la Santé et de la Recherche Medicale, Infection Antimicrobial Modelisation Evolution, U1137, Team Decision Science in Infectious Diseases, Paris, France; Assistance Publique Hôpitaux de Paris, Bichat hospital, Medical and infectious diseases ICU, F75018, Paris France. Electronic address:

Article Synopsis
  • Hospital-acquired bloodstream infections (HA-BSI) in ICU patients can be life-threatening, and this study aimed to see how early adequate antibiotic treatment affects 28-day mortality rates for patients who survive at least one day after infection onset.
  • Using data from a multicenter study with 2,418 patients, researchers found that those who received adequate treatment within 24 hours had a lower 28-day mortality rate (32.8%) compared to those who were inadequately treated (40%).
  • The study concluded that inadequate antibiotic therapy within 24 hours contributes significantly to 28-day mortality, indicating that quicker treatment could greatly improve patient outcomes in cases of HA-BSI.
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Very high gravity (VHG) fermentation is an industrial-scale process utilizing a sugar concentration above 250 g/L to attain a significant ethanol concentration, with the advantages of decreased labor, production costs, water usage, bacterial contamination, and energy consumption. Saccharomyces cerevisiae is one of the most extensively employed organisms in ethanol fermentation through VHG technology. Conversely, high glucose exposure leads to numerous stress factors that negatively impact the ethanol production efficiency of this organism.

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Although the contribution of real patient encounters to medical education is well known, challenges such as a lack of suitable cases, patients not consenting to student involvement, physical space limitations that prevent every student from participating, the inability to replicate the same patient encounter, and reduced patient admissions to healthcare facilities during extraordinary periods are common obstacles that need to be addressed in clinical education. To overcome these challenges, video consultation (VC) recordings, which were made with the consent of patients having a telemedicine consultation, were collected as an archive of medical interview recordings covering a wide spectrum of pulmonary diseases. These recordings were watched by students in a classroom setting during clinical clerkships, with case discussions interspersed.

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  • * A study in Turkey examined the responses of 17 patients with solid tumors and NTRK fusions who received entrectinib, revealing a median age of 42 years and various types of cancer, with NTRK1 and NTRK3 being the most common gene rearrangements.
  • * Results showed a 35.3% objective response rate with side effects leading to dosage reductions in four patients; the median overall survival was 20.8 months
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Objectives: Kidney trauma is the most common urological trauma. Technological advances have made conservative management possible for almost all kidney trauma. However, grade five kidney trauma needs to be carefully examined due to its various complications, especially late complications that often delayed in recognition thus forming irreversible morbidity, with the most common late complication is kidney damage due to ischemic and fibrotic process.

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  • * Current medications can alleviate some symptoms temporarily, but no complete cure has been discovered yet; however, new therapeutic methods are being developed to better understand and treat these diseases.
  • * The CRISPR/Cas technology, which involves editing the genome, shows promise for future treatments, especially when combined with extracellular vesicles (like exosomes) to safely deliver therapies to specific cells without affecting others.
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Objectives: We aimed to report the characteristics of pediatric IgG4-related disease (IgG4-RD) through a multicentre registry, to assess disease clusters, and to evaluate the performances of the 2019 American College of Rheumatology and European League Against Rheumatism (ACR/EULAR) classification criteria and the 2020 revised comprehensive diagnostic (RCD) criteria in this cohort.

Methods: Data of IgG4-RD patients in 13 pediatric rheumatology centers were recorded to a web-based registration system. The diagnosis of IgG4-RD was made according to the 2011 comprehensive diagnostic criteria.

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  • A novel nanocomposite, FeO@coPPy-PTH, was created to efficiently extract and measure metal ions like Co(II), Cr(III), and Ni(II) using advanced techniques without needing a chelating agent.
  • The nanocomposite showed excellent stability and good dispersion in strong acidic solutions, with the size of the FeO nanoparticles ranging from 30 nm to 120 nm after coating.
  • Under optimized conditions, the method provided high precision with low detection limits, and it was effectively applied to analyze metal content in beverages like beer, wine, and nonalcoholic drinks.
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  • Vaccination is crucial in combating pandemics like COVID-19, which has caused significant loss of life and economic downturns, leading to urgent calls for vaccine distribution.
  • A study in Jinja District, Eastern Uganda assessed the knowledge and acceptance of the COVID-19 vaccine among 210 residents, revealing that 45.2% had adequate knowledge and 56.2% were willing to accept the vaccine.
  • Results indicated that higher education levels positively correlated with both knowledge and acceptance of the vaccine, highlighting the need for targeted awareness campaigns, especially via radio and television, to improve public understanding and acceptance.
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Introduction: Chronic urticaria requires well-defined treatment strategies in order to achieve a maximum treatment response and maintain the quality of life. Since 2014, omalizumab has been used in chronic urticaria. However, many studies showed that some patients are resistant to omalizumab.

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  • The study aimed to compare various clinical and hormonal characteristics, treatment methods, and survival outcomes of ectopic Cushing's syndrome (ECS) between male and female patients.
  • Data was collected from 11 medical centers, evaluating 54 patients (28 females and 26 males), and found similarities in age, clinical presentation, and hormone levels despite some differences like higher rates of diabetes and osteoporosis in males.
  • Overall, the results showed comparable disease progression, treatment responses, and remission rates between sexes, but indicated that males experience more severe conditions such as hyperglycemia and osteoporosis.
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Background: The global increase in life expectancy has significantly raised the elderly population. In Türkiye, the proportion of individuals aged 65 and over rose from 8.8% in 2018 to 10.

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