Survival Outcomes of Patients with Primary Plasma Cell Leukemia in the Era of Proteasome Inhibitors and Immunomodulatory Agents: A Real-Life Multicenter Analysis.

Objective: In this study, we aimed to obtain real-life data on the use of antimyeloma agents, which significantly increase overall survival (OS) in multiple myeloma (MM) patients, in primary plasma cell leukemia (pPCL) patients with poor prognosis.

Materials And Methods: Data from 53 patients who were diagnosed with pPCL between 2011 and 2020 and who used at least one proteasome inhibitor (PI) and/or immunomodulatory (IMID) agent were analyzed retrospectively. Depending on the year of the pPCL diagnosis, 20% leukocytes or ≥2x10/L plasma cells in the peripheral blood was used as a diagnostic criterion.

The effect of peer education on high school students' knowledge levels regarding Human Papillomavirus (HPV) infection and vaccination.

Purpose: This study aimed to explore the impact of the peer education model on adolescents' knowledge levels regarding Human Papillomavirus (HPV) infection and HPV vaccination.

Design And Methods: The study was conducted quasi-experimentally in a pretest-posttest single-group design. The study sample consisted of 913 students enrolled in 9th, 10th, and 11th grades.

Nonacute Subdural Hematoma Evacuation Using a Rigid Endoscopy System: A Clinical Study.

Aim: To determine the clinical relevance of a rigid endoscopy surgical method for subdural hematomas, as previously described in a cadaver study.

Material And Methods: Between May 2021 and September 2023, 21 patients underwent subdural hematoma drainage using a 0-degree rigid endoscope. Traumatic acute subdural hematomas were excluded.

Biofilms in modern CaCO-supersaturated freshwater environments reveal viral proxies.

Biofilms are mucilaginous-organic layers produced by microbial activity including viruses. Growing biofilms form microbial mats which enhance sediment stability by binding particles with extracellular polymeric substances and promoting growth through nutrient cycling and organic matter accumulation. They preferentially develop at the sediment-water interface of both marine and non-marine environments, and upon the growing surfaces of modern tufa and travertine.

Secukinumab May Be an Effective Treatment Option for Axial Spondyloarthritis and Psoriatic Arthritis Patients with a History of Malignancy: Multicenter Real-Life Experience from Turkey.

: Secukinumab is a monoclonal antibody against interleukin 17 approved for patients with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), and psoriasis. Treating axSpA and PsA patients with a history of malignancy is a challenge. While initial results on the applicability of secukinumab in this patient group are positive, the number of studies on this topic remains limited.

Meningococcal Carriage in Children with Atypical Hemolytic Uremic Syndrome Receiving Eculizumab Therapy.

Background/objectives: Eculizumab is a first-line treatment for atypical hemolytic uremic syndrome (aHUS), and patients undergoing eculizumab therapy may become more susceptible to infection caused by (). While meningococcal vaccination is required for patients undergoing eculizumab therapy, there is limited knowledge about meningococcal carriage in children with aHUS. We aimed to evaluate (1) the prevalence of carriage, (2) serogroup distribution, and (3) the immunization status of children undergoing eculizumab treatment for aHUS.

Unveiling the Gaps: Analyzing Family Physicians' Perspectives on Infectious Disease Notification in Türkiye.

Objective: This study aimed to assess the opinions, attitudes, and behaviors of family physicians in Türkiye regarding mandatory communicable disease notification.

Design: Cross-sectional study.

Setting: A national online survey in Türkiye.

Investigation of Physical Fitness in Children and Adolescents with Juvenile Idiopathic Arthritis: A Case-Control Study.

Swelling, effusion, tenderness, and pain seen in the joints of juvenile idiopathic arthritis (JIA). This disease may cause limitation in joint movements, muscle weakness, atrophy, balance, and gait disorders. Physical fitness is accepted as an important determinant of health in both childhood and adolescence.

Psychometric evaluation of the Turkish version of the Work-Related Stress Scale: A study among search and rescue workers responding to the 2023 KahramanmaraÅŸ earthquakes.

This study evaluates the reliability and validity of the Turkish version of the Work-Related Stress Scale (WRSS) among search and rescue workers who responded to the 2023 KahramanmaraÅŸ earthquakes. Data were collected from 275 workers between January and April 2024 using the Personal Information Form and the Turkish version of the WRSS. Language, content, and construct validity were assessed, and reliability was determined using item-total correlation, Cronbach's alpha, split-half, and test-retest methods.

Bridging the knowledge gap-microplastics in focus: assessing microplastic pollution awareness among medical students.

Microplastic pollution is a growing environmental and health issue. This study evaluates microplastic pollution awareness among medical students at Pamukkale University and the factors influencing it. A cross-sectional study was conducted in June 2023 with 474 students from the 1st, 3rd, and 6th years, using a 26-item questionnaire, including the 14-item Microplastic Pollution Awareness Scale (MPAS).

Prediction of complications after laparoscopic partial nephrectomy: feasibility of E‑PASS score.

Purpose: With significant advancements in laparoscopic procedures and tools over the last decade, the partial nephrectomy (PN) surgical approach has gradually transformed from open to laparoscopic partial nephrectomy (LPN). Although numerous studies evaluating the postoperative complications of laparoscopic partial nephrectomy can be found in the literature, a scoring system that addresses both preoperative physical condition and intraoperative risk factors has not yet been established. The Estimation of Physiological Ability and Surgical Stress (E-PASS) score is a scoring system that considers both the patient's preoperative condition and intraoperative variables to predict the risk of postoperative complications in surgically treated patients.

The validity of Turkish version of Social Frailty Index in older adults: An index of social attributes predictive of mortality.

Purpose: The aim of this study was to examine the validity of Turkish version of Social Frailty Index in older adults.

Material And Methods: 102 older adults aged 65 and over were included in the study. Hodkinson Mental Test was first applied to older adults.

Biopsychosocial conditions of patients in the rheumatology department of a university hospital.

Introduction: The aim was to examine biopsychosocial conditions of patients hospitalized in the rheumatology department of a university hospital.

Material And Methods: Ninety-six patients (mean age: 53.14 ±16.