114,713 results match your criteria: "Pakistan; Pakistan Institute of Engineering and Applied Sciences[Affiliation]"

Association between inclisiran and the risk of arrhythmias.

Int J Cardiol Heart Vasc

February 2025

Division of Electrophysiology, Department of Cardiology, UPMC Harrisburg, PA 17101, United States.

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Objective: To investigate and compare the median nerve-cross sectional area at the wrist region of the dominant and non-dominant hands of high- and low- smartphone users.

Method: This descriptive cross-sectional study was based on 128 human subjects conducted at Bahria University Health Sciences Karachi Campus from January to June 2022. The sample size was calculated using the method of sample size for frequency in a population www.

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Objective: To explore the effect of seeds powder { 500 mg} capsule in diabetes Type-2 (T2DM) patients in Karachi.

Methods: A randomized selection of 40 T2DM patients from Sindh Government Hospital New Karachi with their consents was done for a non-blinded controlled trial from October to December 2019 and divided into P (Positive Control, metformin 500 mg) & T (Test, + was also included, using the same dosage of CapCASP on twenty healthy volunteers. The data were analyzed using an online graph pad student's t-test and a one-way ANOVA (SPSS version 24) metformin 500mg each).

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PDA-associated infective endocarditis with pulmonary artery perforation.

Pak J Med Sci

January 2025

Muhammad Ali Mumtaz, MD FACS. Tahir Heart Institute, Fazl-e-Omar Hospital, Chenab Nagar, District Chiniot, Pakistan.

Infective endocarditis used to frequently cause mortality in subjects having PDA before the advent of antibiotics and surgical ligation. It has been documented that clinically silent PDAs may cause infective complications of heart valves. We present case of an 18-years-old male who presented with palpitations and fever to our emergency department.

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Background & Objectives: Maternal mortality is a global concern primarily due to preventable obstetric complications. Challenges in implementing Emergency Obstetric Care (EmOC) in developing nations hinder effective reduction of these deaths. Our objective was to identify key challenges in EmOC practices among frontline healthcare providers, assess the severity and frequency of these barriers, and evaluate gaps in resources, training, and institutional support needed for effective resolution.

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Objective: The objective of the study was to assess whether the measurement of the angle of progression in nulliparous women in labour can predict the mode of delivery.

Methods: This prospective observational study was conducted at Benazir Bhutto Hospital, Rawalpindi Medical University from 16 February to 25 March 2024. Nulliparous pregnant women in the active first stage of labour with singleton pregnancy and cephalic presentation were included in the study after taking informed consent.

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Objective: To determine the prevalence of antimicrobial resistance (AMR) in isolated from urine cultures of patients with uncomplicated cystitis in Pakistan. Another objective was to analyze and compare the resistance rates of to specific antibiotics, conducting a year-by-year evaluation of these rates to identify trends and changes over the past seven years.

Methods: Retrospective analysis of susceptibility data of isolated from midstream urine culture samples of patients presenting in outpatient department with uncomplicated cystitis, from January 2016 to December 2022 in the section of Microbiology, Liaquat University of Medical and Health Sciences was done.

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Objective: To determine the diagnostic accuracy and procedure safety of ultrasound-guided core needle biopsy of extra cranial solid masses in the pediatric population.

Method: A cross-sectional survey was conducted by the Department of Pediatric Hematology /Oncology and Radiology at Indus Hospital and Health Network Karachi from August 2022 to April 2023. A total of 118 pediatric patients, from age one month to 18 years, with extra cranial solid masses were studied.

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Objective: To determine the correlation of burnout syndrome with emotional intelligence at workplace.

Methods: This cross-sectional study was conducted in six public sector hospitals of Khyber Pakhtunkhwa between June and November, 2022. Male and female clinicians from Medicine, Surgery, Obstetrics / Gynaecology, Paediatrics Medicine, Paediatric Surgery, Gastroenterology, Anesthesiology, Psychiatry, Radiology, Dermatology, Ophthalmology, Otorhinolaryngology, Nephrology, Urology, Neurology, Neurosurgery, Orthopaedics, Endocrinology, Rheumatology and Cardiology were included in the study.

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Background & Objectives: Poor medication adherence is an essential contributor to Pakistan's high prevalence of uncontrolled hypertension. This study will be aimed to assess the efficacy of a one-of-a-kind developed intervention in improving medication adherence and treatment outcomes in hypertension patients.

Methods: Twleve months duration long randomized controlled trial from January to December 2021 will be carried out at Shaikh Zayed Medical Complex (SZMC), Lahore.

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Objective: This study was conducted to investigate the social media practices and attitudes towards e-professionalism among undergraduate medical students in a medical college of Pakistan.

Methods: This cross-sectional study was conducted on 220 undergraduate medical students from 2 to final-year MBBS, at CMH Lahore Medical College from March to August 2022. After ethical approval, a printed questionnaire was distributed among students, selected by stratified random sampling technique.

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Objectives: To determine the frequency of undiagnosed hypertension among the diabetic patients with micro vascular complications.

Method: This is a descriptive case series conducted at Department of Medicine, Ghurki Trust Teaching Hospital, in this six month stud which enrolled 213 patients between 18-60 years from March 28, 2021 to September 28, 2021, having diabetes with microvascular complications. These patients were not previously diagnosed as hypertensives.

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Maternal Sepsis and associated factors: A multi-central study from two tertiary care hospitals of South Punjab, Pakistan.

Pak J Med Sci

January 2025

Sadia Nazir, FCPS Assistant Professor, Obstetrics and Gynaecology Department, DG Khan Medical College, DG Khan, Pakistan.

Objective: To determine the risk factors and outcomes of maternal sepsis.

Methods: This case-control study was performed at the departments of Obstetrics & Gynecology, Nishtar Hospital, Multan, and Ghazi Khan Hospital, Dera Ghazi Khan, Pakistan, from June 2023 to May 2024. Cases were comprised of females aged 18-45 years diagnosed with maternal sepsis, and admitted during the study period.

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Quality of life in cutaneous leishmaniasis patients in Khyber Pakhtunkhwa, Pakistan.

Pak J Med Sci

January 2025

Khalid Rehman Institute of Public Health & Social Sciences, Khyber Medical University, Peshawar, Pakistan.

Objective: To determine the impact of leishmaniasis on the quality of life of patients visiting the district headquarter hospital in District Khyber, Khyber Pakhtunkhwa, Pakistan.

Methods: A cross-sectional exploratory study was conducted in District Headquarter Hospital of Khyber District, Khyber Pakhtunkhwa from November 2019 to April 2020. In this study, 349 participants who consented were included by using a non-probability consecutive sampling technique.

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Randomized controlled trial on the treatment of Hypoferritinemia without Anemia: Comparing oral and intravenous iron supplementation among reproductive age women in Pakistan.

Pak J Med Sci

January 2025

Dr. Rubeena Zakar, MBBS, PhD Public Health, Department of Public Health, Institute of Social and Cultural Studies, University of Punjab, Lahore, Pakistan.

Background & Objectives: Hypoferritinemia without anemia (HWA) is an under-recognized public health concern. Early identification and targeted treatment of HWA can prevent unnecessary medication use and potential drug abuse. This study aims to establish clearer guidelines for recognizing and managing HWA, improving patient's outcome.

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Short and long-term outcome of levamisole in early versus late steroid responsive nephrotic syndrome: A single centre experience.

Pak J Med Sci

January 2025

Khemchand N Moorani, MBBS, MCPS, FCPS, IPNA Pediatr Nephrol fellowship Professor, Department of Pediatric Nephrology, The Kidney Centre Post Graduate Training Institute, Karachi. 197/9, Rafiqui Shaheed Road, Karachi-75530, Pakistan.

Objectives: To determine the effectiveness of Levamisole (Leva) in maintaining short-term and long-term remission in early steroid responders (ESRs) and late steroid responders (LSRs).

Methods: This retrospective study on 106 cohorts, aged 2-14 years with frequent-relapsing (FR) and steroid-dependent nephrotic syndrome (SDNS) who received Leva over 10-years (2012-2023), was carried out at tertiary care centre, Karachi from January-August 2023. Patients were categorized based on steroid response during first episode of NS as ESRs if complete remission (CR) was achieved within two weeks of daily steroid and LSRs if CR achieved between two-four weeks.

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Objective: To compare the efficacy of a probiotic plus antibiotic with antibiotic therapy alone for the prevention of the recurrence of bacterial vaginosis.

Method: A Randomized control trial was conducted in the Gynecological Department of Nishtar Hospital, Multan, between July 2022 and June 2023. One hundred and twenty (N=120) women with bacterial vaginosis, all cured with metronidazole, were enrolled and randomized.

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Association between Emotional Intelligence and Professionalism in Medical Students: The Compassion-Competence Nexus.

Pak J Med Sci

January 2025

Syed Imran Mehmood, MBBS, MA, MMedED (UK), PhD (Netherlands) Dow Institute of Health Professionals Education, Dow University of Health Sciences, Karachi, Pakistan.

Background And Objective: In medical education, the challenging constructs of emotional intelligence and professionalism are increasingly being addressed worldwide and seem to share common characteristic components. The objective of this study was to determine the association between emotional intelligence and professionalism as perceived and self-reported by medical students and to explore the gender difference in these two variables.

Methods: It is a cross-sectional study of eight months duration, from February-September 2019, that included final year medical students at Dow Medical College through convenience sampling.

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The burden of cutaneous fungal infections in a tertiary care hospital in Pakistan.

Pak J Med Sci

January 2025

Aisha Faheem, M.Sc. (Biotechnology), MBA (Pharmaceutical Management) Research Assistant, Dow Research Institute of, Biotechnology and Biomedical Sciences, Karachi Pakistan.

Objective: In Pakistan, the real extent of fungal infection is unknown. Our objective was to estimate the burden of major fungal diseases here to emphasize their public health importance.

Methods: In this retrospective study, the medical records (January 2019 - December 2019) of 863 patients diagnosed with superficial fungal infection (SFI) were reviewed at the dermatology department of Aga Khan University Hospital (AKUH) Karachi.

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Objectives: To determine gender and ethnic distribution of developmental dysplasia of hip in newborns using Graf method for ultrasound. To determine the significance of association between developmental dysplasia of hip with ethnicity in newborns using Graf's method ultrasound.

Method: This analytical cross-sectional observational study was conducted in Karachi from January through June 2022 .

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Objective: To determine the relationship between sleep pattern dysfunction with stress, anxiety and depression among pregnant women in a tertiary care hospital.

Method: An analytical cross-sectional study was conducted at Dr. Ruth K.

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Neurological disorders in Pregnancy: Radiological insights and Obstetric implications.

Pak J Med Sci

January 2025

Huma Shams, MBB Department of Obstetrics and Gynaecology, Medical Teaching Institute, Lady Reading Hospital, Peshawar, Pakistan.

Objective: To explore the radiological findings of neurological disorders in obstetrics patients, their obstetric and fetal outcome.

Method: The cross-sectional study was conducted at Lady Ready Hospital (LRH), Peshawar from June 2022 till March, 2023. Sixty two obstetric patients with neurological symptoms were included.

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Harm reduction associated with heated tobacco products: A systematic review and meta-analysis.

Pak J Med Sci

January 2025

Professor Khalid S. Khan, MSc. Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain.

Objective: We conducted a systematic review and meta-analysis of randomised studies in humans comparing the outcomes of switching to heated tobacco products (HTPs) versus continuing conventional tobacco smoking by burning.

Methods: We searched the electronic databases which included PubMed, Web of Science, Cochrane Controlled Trials Register, and Google Scholar from inception to May 2023. Randomised Controlled Trials (RCTs) in humans comparing HTPs with conventional burnt tobacco products were selected.

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Background & Objective: Determination of axillary lymph-node status plays a pivotal role in decision making for breast cancer treatment. Biopsy is the current standard of care but hold risks of complications as well. We aimed to find out the correlation of sonographic features of lymph node and histo-pathological findings, to predict axillary lymph-node metastasis in breast cancer patients.

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Objectives: To determine the prevalence of family planning practice among the parents of children affected with beta thalassemia major (BTM) and to determine the relationship between various factors and family planning practice in Makran division Balochistan.

Methods: A cross-sectional observational study was conducted on 190 parents having BTM children registered in thalassemia care centers throughout the Makran division from May 2023 to October 2023. The structured questionnaire was used and data was collected using the non-probability convenience technique.

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